Leyhausen G, Lorenz B, Zhu H, Geurtsen W, Bohnensack R, M€ uller WEG, Schr€ oder HC (1998)
Inorganic polyphosphate in human osteoblast-like cells. J Bone Miner Res 13:803–812
Li Q, Kannan A, Wang W, Demayo FJ, Taylor RN, Bagchi MK, Bagchi IC (2007) Bone
morphogenetic protein 2 functions via a conserved signaling pathway involving Wnt4 to
regulate uterine decidualization in the mouse and the human. J Biol Chem 282:31725–31732
Lo ´pez-Alvarez M, Solla EL, Gonza ´lez P, Serra J, Leo ´n B, Marques AP, Reis RL (2009) Siliconhydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and silica. Study of
adhesion and proliferation of osteoblast-like cells. J Mater Sci Mater Med 20:1131–1136
Lorenz B, Schr€ oder HC (2001) Mammalian intestinal alkaline phosphatase acts as highly active
exopolyphosphatase. Biochim Biophys Acta 1547:254–261
MacDonald HM, Hardcastle AE, Jugdaohsingh R, Reid DM, Powell JJ (2005) Dietary silicon
intake is associated with bone mineral density in premenopasual women and postmenopausal
women taking HRT. J Bone Miner Res 20:S393
Maehira F, Iinuma Y, Eguchi Y, Miyagi I, Teruya S (2008) Effects of soluble silicon compound
and deep-sea water on biochemical and mechanical properties of bone and the related gene
expression in mice. J Bone Miner Metab 26:446–455
Maehira F, Miyagi I, Eguchi Y (2009) Effects of calcium sources and soluble silicate on bone
metabolism and the related gene expression in mice. Nutrition 25:581–589
Mann S (2001) Biomineralization: principles and concepts in bioinorganic materials chemistry.
Oxford University Press, Oxford
McNaughton SA, Bolton-Smith C, Mishra GD, Jugdaohsingh R, Powell JJ (2005) Dietary silicon
intake in post-menopausal women. Br J Nutr 94:813–817
Matsuzaki K, Katayama K, Takahashi Y, Nakamura I, Udagawa N, Tsurukai T, Nishinakamura R,
Toyama Y, Yabe Y, Hori M, Takahashi N, Suda T (1999) Human osteoclast-like cells are
formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected
with the parathyroid hormone (PTH)/PTH-related protein receptor gene. Endocrinology
140:925–932
Morgan EF, Barnes GL, Einhorn TA (2008) The bone organ system: form and function. In: Marcus
R, Feldman D, Nelson DA, Rosen CJ (eds) Osteoporosis., 3rd edn. Elsevier, San Diego,
pp 3–25
Mori K, Berreur M, Blanchard F, Chevalier C, Guisle-Marsollier I, Masson M, Re ´dini F, Heymann
D (2007) Receptor activator of nuclear factor-kB ligand (RANKL) directly modulates the
gene expression profile of RANK-positive Saos-2 human osteosarcoma cells. Oncol Rep
18:1365–1371
Morse DE (1999) Silicon biotechnology: harnessing biological silica production to construct new
materials. Trends Biotechnol 17:230–232
M€ uller WEG (2003) Silicon biomineralization: biology-biochemistry-molecular biologybiotechnology. Springer, Berlin
M€ uller WEG, Rothenberger M, Boreiko A, Tremel W, Reiber A, Schr€ oder HC (2005) Formation
of siliceous spicules in the marine demosponge Suberites domuncula. Cell Tissue Res
321:285–297
M€ uller WE, Belikov SI, Tremel W, Perry CC, Gieskes WW, Boreiko A, Schr€ oder HC (2006)
Siliceous spicules in marine demosponges (example Suberites domuncula). Micron
37:107–120
M€ uller WEG, Boreiko A, Wang XH, Krasko A, Geurtsen W, Custo ´dio MR, Winkler T,
Lukic ´-Bilela L, Link T, Schr€ oder HC (2007a) Morphogenetic activity of silica and bio-silica
on the expression of genes, controlling biomineralization using SaOS-2 cells. Calcif Tissue Int
81:382–393
M€ uller WEG, Wang XM, Belikov SI, Tremel W, Schloßmacher U, Natoli A, Brandt D, Boreiko A,
Tahir MN, M€ uller IM, Schr€ oder HC (2007b) Formation of siliceous spicules in demosponges:
example Suberites domuncula. In: B€ auerlein E (ed) Handbook of biomineralization; Vol. 1:
biological aspects and structure formation. Wiley-VCH, Weinheim, pp 59–82
308
H.C. Schr€ oder et al.
Inorganic polyphosphate in human osteoblast-like cells. J Bone Miner Res 13:803–812
Li Q, Kannan A, Wang W, Demayo FJ, Taylor RN, Bagchi MK, Bagchi IC (2007) Bone
morphogenetic protein 2 functions via a conserved signaling pathway involving Wnt4 to
regulate uterine decidualization in the mouse and the human. J Biol Chem 282:31725–31732
Lo ´pez-Alvarez M, Solla EL, Gonza ´lez P, Serra J, Leo ´n B, Marques AP, Reis RL (2009) Siliconhydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and silica. Study of
adhesion and proliferation of osteoblast-like cells. J Mater Sci Mater Med 20:1131–1136
Lorenz B, Schr€ oder HC (2001) Mammalian intestinal alkaline phosphatase acts as highly active
exopolyphosphatase. Biochim Biophys Acta 1547:254–261
MacDonald HM, Hardcastle AE, Jugdaohsingh R, Reid DM, Powell JJ (2005) Dietary silicon
intake is associated with bone mineral density in premenopasual women and postmenopausal
women taking HRT. J Bone Miner Res 20:S393
Maehira F, Iinuma Y, Eguchi Y, Miyagi I, Teruya S (2008) Effects of soluble silicon compound
and deep-sea water on biochemical and mechanical properties of bone and the related gene
expression in mice. J Bone Miner Metab 26:446–455
Maehira F, Miyagi I, Eguchi Y (2009) Effects of calcium sources and soluble silicate on bone
metabolism and the related gene expression in mice. Nutrition 25:581–589
Mann S (2001) Biomineralization: principles and concepts in bioinorganic materials chemistry.
Oxford University Press, Oxford
McNaughton SA, Bolton-Smith C, Mishra GD, Jugdaohsingh R, Powell JJ (2005) Dietary silicon
intake in post-menopausal women. Br J Nutr 94:813–817
Matsuzaki K, Katayama K, Takahashi Y, Nakamura I, Udagawa N, Tsurukai T, Nishinakamura R,
Toyama Y, Yabe Y, Hori M, Takahashi N, Suda T (1999) Human osteoclast-like cells are
formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected
with the parathyroid hormone (PTH)/PTH-related protein receptor gene. Endocrinology
140:925–932
Morgan EF, Barnes GL, Einhorn TA (2008) The bone organ system: form and function. In: Marcus
R, Feldman D, Nelson DA, Rosen CJ (eds) Osteoporosis., 3rd edn. Elsevier, San Diego,
pp 3–25
Mori K, Berreur M, Blanchard F, Chevalier C, Guisle-Marsollier I, Masson M, Re ´dini F, Heymann
D (2007) Receptor activator of nuclear factor-kB ligand (RANKL) directly modulates the
gene expression profile of RANK-positive Saos-2 human osteosarcoma cells. Oncol Rep
18:1365–1371
Morse DE (1999) Silicon biotechnology: harnessing biological silica production to construct new
materials. Trends Biotechnol 17:230–232
M€ uller WEG (2003) Silicon biomineralization: biology-biochemistry-molecular biologybiotechnology. Springer, Berlin
M€ uller WEG, Rothenberger M, Boreiko A, Tremel W, Reiber A, Schr€ oder HC (2005) Formation
of siliceous spicules in the marine demosponge Suberites domuncula. Cell Tissue Res
321:285–297
M€ uller WE, Belikov SI, Tremel W, Perry CC, Gieskes WW, Boreiko A, Schr€ oder HC (2006)
Siliceous spicules in marine demosponges (example Suberites domuncula). Micron
37:107–120
M€ uller WEG, Boreiko A, Wang XH, Krasko A, Geurtsen W, Custo ´dio MR, Winkler T,
Lukic ´-Bilela L, Link T, Schr€ oder HC (2007a) Morphogenetic activity of silica and bio-silica
on the expression of genes, controlling biomineralization using SaOS-2 cells. Calcif Tissue Int
81:382–393
M€ uller WEG, Wang XM, Belikov SI, Tremel W, Schloßmacher U, Natoli A, Brandt D, Boreiko A,
Tahir MN, M€ uller IM, Schr€ oder HC (2007b) Formation of siliceous spicules in demosponges:
example Suberites domuncula. In: B€ auerlein E (ed) Handbook of biomineralization; Vol. 1:
biological aspects and structure formation. Wiley-VCH, Weinheim, pp 59–82
308
H.C. Schr€ oder et al.