232
E. C. Bailey et al.
Motzny CK, Holmgren R (1995) The Drosophila Cubitus interruptus protein
and its role in the wingless and hedgehog signal transduction pathways.
Mech Dev 52:137-150
Nakano Y, Guerrero I, Hidalgo A, Taylor A, Whittle JR, Ingham PW (1989) A
protein with several possible membrane-spanning domains encoded by the
Drosophila segment polarity gene patched. Nature 341 :508-513
Nohturfft A, Hua X, Brown MS, Goldstein JL (1996) Recurrent G-to-A substitution in a single codon of SREBP cleavage- activating protein causes sterol
resistance in three mutant Chinese hamster ovary cell lines. Proc Natl Acad
Sci USA 93:13709-13714
Nohturfft A, Brown MS, Goldstein JL (1998) Topology of SREBP cleavageactivating protein, a poly topic membrane protein with a sterol-sensing domain. J BioI Chern 273:17243-17250
Nusslein-Volhard C, Wieschaus E (1980) Mutations affecting segment number
and polarity in Drosophila. Nature 287:795-801
Ohlmeyer JT, Kalderon D (1998) Hedgehog stimulates maturation of Cubitus
interruptus into a labile transcriptional activator. Nature 396:749-753
Orenic TV, Slusarski DC, Kroll KL, Holmgren RA (1990) Cloning and characterization of the segment polarity gene Cubitus interruptus Dominant of
Drosophila. Genes Dev 4:1053-1067
Oro AE, Higgins KM, Hu Z, Bonifas JM, Epstein E, Jr., Scott MP (1997) Basal cell carcinomas in mice overexpressing sonic hedgehog. Science
276:817-821
Pan D, Rubin GM (1995) cAMP-dependent protein kinase and hedgehog act
antagonistically in regulating decapentaplegic transcription in Drosophila
imaginal discs. Cell 80:543-552
Pentchev PG, Comly ME, Kruth HS, Tokoro T, Butler J, Sokol J, Filling-Katz
M, Quirk JM, Marshall DC, Patel S (1987) Group C Niemann-Pick disease:
faulty regulation of low-density lipoprotein uptake and cholesterol storage
in cultured fibroblasts. FASEB J 1:40-45
Pham A, Therond P, Alves G, Toumier FB, Busson D, Lamour-Isnard C,
Bouchon BL, Preat T, Tricoire H (1995) The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment. Genetics 140:587-598
Pietsch T, Waha A, Koch A, Kraus J, Albrecht S, Tonn J, Sorensen N, Berthold
F, Henk B, Schmandt N, Wolf HK, von Deimling A, Wainwright B,
Chenevix-Trench G, Wiestler OD, Wicking C (1997) Medulloblastomas of
the desmoplastic variant carry mutations of the human homologue of
Drosophila patched. Cancer Res 57:2085-2088
Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA
(1995) The product of hedgehog autoproteolytic cleavage active in local
and long-range signalling. Nature 374:363-366
E. C. Bailey et al.
Motzny CK, Holmgren R (1995) The Drosophila Cubitus interruptus protein
and its role in the wingless and hedgehog signal transduction pathways.
Mech Dev 52:137-150
Nakano Y, Guerrero I, Hidalgo A, Taylor A, Whittle JR, Ingham PW (1989) A
protein with several possible membrane-spanning domains encoded by the
Drosophila segment polarity gene patched. Nature 341 :508-513
Nohturfft A, Hua X, Brown MS, Goldstein JL (1996) Recurrent G-to-A substitution in a single codon of SREBP cleavage- activating protein causes sterol
resistance in three mutant Chinese hamster ovary cell lines. Proc Natl Acad
Sci USA 93:13709-13714
Nohturfft A, Brown MS, Goldstein JL (1998) Topology of SREBP cleavageactivating protein, a poly topic membrane protein with a sterol-sensing domain. J BioI Chern 273:17243-17250
Nusslein-Volhard C, Wieschaus E (1980) Mutations affecting segment number
and polarity in Drosophila. Nature 287:795-801
Ohlmeyer JT, Kalderon D (1998) Hedgehog stimulates maturation of Cubitus
interruptus into a labile transcriptional activator. Nature 396:749-753
Orenic TV, Slusarski DC, Kroll KL, Holmgren RA (1990) Cloning and characterization of the segment polarity gene Cubitus interruptus Dominant of
Drosophila. Genes Dev 4:1053-1067
Oro AE, Higgins KM, Hu Z, Bonifas JM, Epstein E, Jr., Scott MP (1997) Basal cell carcinomas in mice overexpressing sonic hedgehog. Science
276:817-821
Pan D, Rubin GM (1995) cAMP-dependent protein kinase and hedgehog act
antagonistically in regulating decapentaplegic transcription in Drosophila
imaginal discs. Cell 80:543-552
Pentchev PG, Comly ME, Kruth HS, Tokoro T, Butler J, Sokol J, Filling-Katz
M, Quirk JM, Marshall DC, Patel S (1987) Group C Niemann-Pick disease:
faulty regulation of low-density lipoprotein uptake and cholesterol storage
in cultured fibroblasts. FASEB J 1:40-45
Pham A, Therond P, Alves G, Toumier FB, Busson D, Lamour-Isnard C,
Bouchon BL, Preat T, Tricoire H (1995) The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment. Genetics 140:587-598
Pietsch T, Waha A, Koch A, Kraus J, Albrecht S, Tonn J, Sorensen N, Berthold
F, Henk B, Schmandt N, Wolf HK, von Deimling A, Wainwright B,
Chenevix-Trench G, Wiestler OD, Wicking C (1997) Medulloblastomas of
the desmoplastic variant carry mutations of the human homologue of
Drosophila patched. Cancer Res 57:2085-2088
Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA
(1995) The product of hedgehog autoproteolytic cleavage active in local
and long-range signalling. Nature 374:363-366