Hedgehog Signaling in Animal Development and Human Disease 231
Li W, Ohlmeyer JT, Lane ME, Kalderon D (1995) Function of protein kinase A
in hedgehog signal transduction and Drosophila imaginal disc development.
Cell 80:553-562
Liscum L, Faust JR (1987) Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick
type C fibroblasts. J BioI Chern 262: 17002-17008
Litingtung Y, Lei L, Westphal H, Chiang C (1998) Sonic hedgehog is essential
to foregut development. Nat Genet 20:58-61
Loftus SK, Morris JA, Carstea ED, Gu JZ, Cummings C, Brown A, Ellison J,
Ohno K, Rosenfeld MA, Tagle DA, Pentchev PG, Pavan WJ (1997) Murine
model of Niemann-Pick C disease: mutation in a cholesterol homeostasis
gene. Science 277:232-235
Maesawa C, Tamura G, Iwaya T, Ogasawara S, Ishida K, Sato N, Nishizuka S,
Suzuki Y, Ikeda K, Aoki K, Saito K, Satodate R (1998) Mutations in the human homologue of the Drosophila patched gene in esophageal squamous
cell carcinoma. Genes Chromosomes Cancer 21:276-279
Marigo V, Tabin CJ (1996) Regulation of patched by Sonic hedgehog in the
developing neural tube. Proc Nat! Acad Sci USA 93:9346-9351
Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ (1996) Biochemical
evidence that patched is the Hedgehog receptor. Nature 384: 176-179
Marigo V, Johnson RL, Vortkamp A, Tabin CJ (1996) Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.
Dev BioI 180:273-283
McGarvey TW, Maruta Y, Tomaszewski JE, Linnenbach AJ, Malkowicz SB
(1998) PTCH gene mutations in invasive transitional cell carcinoma of the
bladder. Oncogene 17:1167-1172
Miller DL, Weinstock MA (1994) Nonmelanoma skin cancer in the United
'States: incidence. JAm Acad DermatoI30:774-778
Mohler J, Vani K (1992) Molecular organization and embryonic expression of
the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Development 115:957-971
Monnier V, Dussillol F, Alves G, Lamour-Isnard C, Plessis A (1998) Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling
pathway. CUff BioI 8:583-586
Motoyama J, Heng H, Crackower MA, Takabatake T, Takeshima K, Tsui LC,
Hui C (1998) Overlapping and non-overlapping ptch2 expression with shh
during mouse embryogenesis. Mech Dev 78:81-84
Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC (1998) Essential function
of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat
Genet 20:54-57
Motoyama J, Takabatake T, Takeshima K, Hui C (1998) Ptch2, a second mouse
Patched gene is co-expressed with Sonic hedgehog. Nat Genet 18: 104-106
Li W, Ohlmeyer JT, Lane ME, Kalderon D (1995) Function of protein kinase A
in hedgehog signal transduction and Drosophila imaginal disc development.
Cell 80:553-562
Liscum L, Faust JR (1987) Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick
type C fibroblasts. J BioI Chern 262: 17002-17008
Litingtung Y, Lei L, Westphal H, Chiang C (1998) Sonic hedgehog is essential
to foregut development. Nat Genet 20:58-61
Loftus SK, Morris JA, Carstea ED, Gu JZ, Cummings C, Brown A, Ellison J,
Ohno K, Rosenfeld MA, Tagle DA, Pentchev PG, Pavan WJ (1997) Murine
model of Niemann-Pick C disease: mutation in a cholesterol homeostasis
gene. Science 277:232-235
Maesawa C, Tamura G, Iwaya T, Ogasawara S, Ishida K, Sato N, Nishizuka S,
Suzuki Y, Ikeda K, Aoki K, Saito K, Satodate R (1998) Mutations in the human homologue of the Drosophila patched gene in esophageal squamous
cell carcinoma. Genes Chromosomes Cancer 21:276-279
Marigo V, Tabin CJ (1996) Regulation of patched by Sonic hedgehog in the
developing neural tube. Proc Nat! Acad Sci USA 93:9346-9351
Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ (1996) Biochemical
evidence that patched is the Hedgehog receptor. Nature 384: 176-179
Marigo V, Johnson RL, Vortkamp A, Tabin CJ (1996) Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.
Dev BioI 180:273-283
McGarvey TW, Maruta Y, Tomaszewski JE, Linnenbach AJ, Malkowicz SB
(1998) PTCH gene mutations in invasive transitional cell carcinoma of the
bladder. Oncogene 17:1167-1172
Miller DL, Weinstock MA (1994) Nonmelanoma skin cancer in the United
'States: incidence. JAm Acad DermatoI30:774-778
Mohler J, Vani K (1992) Molecular organization and embryonic expression of
the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Development 115:957-971
Monnier V, Dussillol F, Alves G, Lamour-Isnard C, Plessis A (1998) Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling
pathway. CUff BioI 8:583-586
Motoyama J, Heng H, Crackower MA, Takabatake T, Takeshima K, Tsui LC,
Hui C (1998) Overlapping and non-overlapping ptch2 expression with shh
during mouse embryogenesis. Mech Dev 78:81-84
Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC (1998) Essential function
of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat
Genet 20:54-57
Motoyama J, Takabatake T, Takeshima K, Hui C (1998) Ptch2, a second mouse
Patched gene is co-expressed with Sonic hedgehog. Nat Genet 18: 104-106