Hedgehog Signaling in Animal Development and Human Disease 229
Gailani MR, Stahle-Backdahl M, Leffel! DJ, Glynn M, Zaphiropoulos PG,
Pressman C, Unden AB, Dean M, Brash DE, Bale AE, Toftgard R (1996)
The role of the human homologue of Drosophila patched in sporadic basal
cell carcinomas. Nat Genet 14:78-81
Gayther SA, Warren W, Mazoyer S, Russell PA, Harrington PA, Chiano M,
Seal S, Hamoudi R, van Rensburg EJ, Dunning AM, et al. (1995) Germline
mutations of the BRCA 1 gene in breast and ovarian cancer families provide
evidence for a genotype-phenotype correlation. Nat Genet 11 :428-433
Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP (1996) Conservation of the hedgehog/patched signaling pathway from flies to mice: induction
ofa mouse patched gene by Hedgehog. Genes Dev 10:301-312
Goodrich LV, Milenkovic L, Higgins KM, Scott MP (1997) Altered neural cell
fates and medulloblastoma In mouse patched mutants. Science
277: I 109-1113
Gorlin RJ (1995) Nevoid basal cell carcinoma syndrome. Dermatol Clin
13:ll3-125
Grindley JC, Bellusci S, Perkins D, Hogan BL (1997) Evidence for the involvement of the Gli gene family in embryonic mouse lung development.
Dev Bioi 188:337-348
Griswold MD (1995) Interactions between germ cells and Sertoli cells in the
testis. Bioi Reprod 52:2ll-216
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K,
Smyth I, Pressman C, Leffel! DJ, Gerrard B, Goldstein AM, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale AE (1996) Mutations of
the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cel!85:841-851
Hahn H, Wojnowski L, Zimmer AM, Hal! J, Miller G, Zimmer A (1998) Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin
syndrome. Nat Med 4:619-622
Hidalgo A (1991) Interactions between segment polarity genes and the generation of the segmental pattern in Drosophila. Mech Dev 35:77-87
Hidalgo A, Ingham P (1990) Cell patterning in the Drosophila segment: spatial
regulation of the segment polarity gene patched. Development 110:291-301
Hooper JE, Scott MP (1989) The Drosophila patched gene encodes a putative
membrane protein required for segmental patterning. Cell 59:751-765
Hui CC, Joyner AL (1993) A mouse model of Greig cephalopolysyndactyly
syndrome: the extra-toes mutation contains an intragenic deletion of the
Gli3 gene. Nat Genet 3:241-246
Hynes M, Stone DM, Dowd M, Pitts-Meek S, Goddard A, Gurney A, Rosenthal A (1997) Control of cell pattern in the neural tube by the zinc finger
transcription factor and oncogene Gli-l. Neuron 19: 15-26
Gailani MR, Stahle-Backdahl M, Leffel! DJ, Glynn M, Zaphiropoulos PG,
Pressman C, Unden AB, Dean M, Brash DE, Bale AE, Toftgard R (1996)
The role of the human homologue of Drosophila patched in sporadic basal
cell carcinomas. Nat Genet 14:78-81
Gayther SA, Warren W, Mazoyer S, Russell PA, Harrington PA, Chiano M,
Seal S, Hamoudi R, van Rensburg EJ, Dunning AM, et al. (1995) Germline
mutations of the BRCA 1 gene in breast and ovarian cancer families provide
evidence for a genotype-phenotype correlation. Nat Genet 11 :428-433
Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP (1996) Conservation of the hedgehog/patched signaling pathway from flies to mice: induction
ofa mouse patched gene by Hedgehog. Genes Dev 10:301-312
Goodrich LV, Milenkovic L, Higgins KM, Scott MP (1997) Altered neural cell
fates and medulloblastoma In mouse patched mutants. Science
277: I 109-1113
Gorlin RJ (1995) Nevoid basal cell carcinoma syndrome. Dermatol Clin
13:ll3-125
Grindley JC, Bellusci S, Perkins D, Hogan BL (1997) Evidence for the involvement of the Gli gene family in embryonic mouse lung development.
Dev Bioi 188:337-348
Griswold MD (1995) Interactions between germ cells and Sertoli cells in the
testis. Bioi Reprod 52:2ll-216
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K,
Smyth I, Pressman C, Leffel! DJ, Gerrard B, Goldstein AM, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale AE (1996) Mutations of
the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cel!85:841-851
Hahn H, Wojnowski L, Zimmer AM, Hal! J, Miller G, Zimmer A (1998) Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin
syndrome. Nat Med 4:619-622
Hidalgo A (1991) Interactions between segment polarity genes and the generation of the segmental pattern in Drosophila. Mech Dev 35:77-87
Hidalgo A, Ingham P (1990) Cell patterning in the Drosophila segment: spatial
regulation of the segment polarity gene patched. Development 110:291-301
Hooper JE, Scott MP (1989) The Drosophila patched gene encodes a putative
membrane protein required for segmental patterning. Cell 59:751-765
Hui CC, Joyner AL (1993) A mouse model of Greig cephalopolysyndactyly
syndrome: the extra-toes mutation contains an intragenic deletion of the
Gli3 gene. Nat Genet 3:241-246
Hynes M, Stone DM, Dowd M, Pitts-Meek S, Goddard A, Gurney A, Rosenthal A (1997) Control of cell pattern in the neural tube by the zinc finger
transcription factor and oncogene Gli-l. Neuron 19: 15-26