228
E. C. Bailey et al.
Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, Cummings C, Gu
J, Rosenfeld MA, Pavan WJ, Krizman DB, Nagle J, Polymeropoulos MH,
Sturley SL, Ioannou VA, Higgins ME, Comly M, Cooney A, Brown A,
Kaneski CR, Blanchette-Mackie EJ, Dwyer NK, Neufeld EB, Chang TY,
Liscum L, Strauss JF, Ohno K, Zeigler M, Carmi R, Sokol J, Markie D,
O'Neill RR, van Diggelen OP, Elleder M, Patterson MC, Brady RO, Vanier
MT, Pentchev PG, Tagle DA (1997) Niemann-Pick Cl disease gene: homology to mediators of cholesterol homeostasis. Science 277:228-231
Chen Y, Struhl G (1996) Dual roles for patched in sequestering and transducing Hedgehog. Cell 87:553-563
Chen Y, Struhl G (1998) In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor
complex. Development 125:4943-4948
Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA
(1996) Cyclopia and defective axial patterning in mice lacking Sonic
hedgehog gene function. Nature 383:407-413
Chidambaram A, Goldstein AM, Gailani MR, Gerrard B, Bale SJ, DiGiovanna
JJ, Bale AE, Dean M (1996) Mutations in the human homologue of the
Drosophila patched gene in Caucasian and African-American nevoid basal
cell carcinoma syndrome patients. Cancer Res 56:4599-4601
Concordet JP, Lewis KE, Moore JW, Goodrich LV, Johnson RL, Scott MP, Ingham PW (1996) Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and
somite patterning. Development 122:2835-2846
Cooper MK, Porter JA, Young KE, Beachy PA (1998) Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 280: 1603-1607
de Kretser DM, Loveland KL, Meinhardt A, Simorangkir D, Wreford N (1998)
Spermatogenesis. Hum Reprod 13:1-8
Epps JL, Jones JB, Tanda S (1997) oroshigane, a new segment polarity gene of
Drosophila melanogaster, functions in hedgehog signal transduction. Genetics 145:1041-1052
Evans DG, Farndon PA, Burnell LD, Gattamaneni HR, Birch JM (1991) The
incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br J Cancer 64:959-961
Fan H, Oro AE, Scott MP, Khavari PA (1997) Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat
Med 3:788-792
Fitzky BU, Witsch-Baumgartner M, Erdel M, Lee IN, Paik YK, Glossmann H,
Utermann G, Moebius FF (1998) Mutations in the Delta7-sterol reductase
gene in patients with the Smith-Lemli-Opitz syndrome. Proc Natl Acad Sci
USA 95:8181-8186
E. C. Bailey et al.
Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, Cummings C, Gu
J, Rosenfeld MA, Pavan WJ, Krizman DB, Nagle J, Polymeropoulos MH,
Sturley SL, Ioannou VA, Higgins ME, Comly M, Cooney A, Brown A,
Kaneski CR, Blanchette-Mackie EJ, Dwyer NK, Neufeld EB, Chang TY,
Liscum L, Strauss JF, Ohno K, Zeigler M, Carmi R, Sokol J, Markie D,
O'Neill RR, van Diggelen OP, Elleder M, Patterson MC, Brady RO, Vanier
MT, Pentchev PG, Tagle DA (1997) Niemann-Pick Cl disease gene: homology to mediators of cholesterol homeostasis. Science 277:228-231
Chen Y, Struhl G (1996) Dual roles for patched in sequestering and transducing Hedgehog. Cell 87:553-563
Chen Y, Struhl G (1998) In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor
complex. Development 125:4943-4948
Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA
(1996) Cyclopia and defective axial patterning in mice lacking Sonic
hedgehog gene function. Nature 383:407-413
Chidambaram A, Goldstein AM, Gailani MR, Gerrard B, Bale SJ, DiGiovanna
JJ, Bale AE, Dean M (1996) Mutations in the human homologue of the
Drosophila patched gene in Caucasian and African-American nevoid basal
cell carcinoma syndrome patients. Cancer Res 56:4599-4601
Concordet JP, Lewis KE, Moore JW, Goodrich LV, Johnson RL, Scott MP, Ingham PW (1996) Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and
somite patterning. Development 122:2835-2846
Cooper MK, Porter JA, Young KE, Beachy PA (1998) Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 280: 1603-1607
de Kretser DM, Loveland KL, Meinhardt A, Simorangkir D, Wreford N (1998)
Spermatogenesis. Hum Reprod 13:1-8
Epps JL, Jones JB, Tanda S (1997) oroshigane, a new segment polarity gene of
Drosophila melanogaster, functions in hedgehog signal transduction. Genetics 145:1041-1052
Evans DG, Farndon PA, Burnell LD, Gattamaneni HR, Birch JM (1991) The
incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br J Cancer 64:959-961
Fan H, Oro AE, Scott MP, Khavari PA (1997) Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat
Med 3:788-792
Fitzky BU, Witsch-Baumgartner M, Erdel M, Lee IN, Paik YK, Glossmann H,
Utermann G, Moebius FF (1998) Mutations in the Delta7-sterol reductase
gene in patients with the Smith-Lemli-Opitz syndrome. Proc Natl Acad Sci
USA 95:8181-8186