Hedgehog Signaling in Animal Development and Human Disease 227
References
Ahn J, Ludecke HJ, Lindow S, Horton WA, Lee B, Wagner MJ, Horsthemke
B, Wells DE (1995) Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXTl). Nat Genet 11: 137-143
Akimaru H, Chen Y, Dai P, Hou DX, Nonaka M, Smolik SM, Armstrong S,
Goodman RH, Ishii S (1997) Drosophila CBP is a co-activator of cubitus
interruptus in hedgehog signalling. Nature 386:735-738
A1cedo J, Ayzenzon M, Von Ohlen T, Noll M, Hooper JE (1996) The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative
receptor for the hedgehog signal. Cell 86:221-232
Alves G, Limbourg-Bouchon B, Tricoire H, Brissard-Zahraoui J, Lamour-Isnard C, Busson D (1998) Modulation of hedgehog target gene expression
by the fused serine- threonine kinase in wing imaginal discs. Mech Dev
78:17-31
Aszterbaum M, Rothman A, Johnson RL, Fisher M, Xie J, Bonifas JM, Zhang
X, Scott MP, Epstein EH Jr (1998) Identification of mutations in the human
PATCHED gene in sporadic basal cell carcinomas and in patients with the
basal cell nevus syndrome. J Invest DermatolllO:885-888
Aza-Blanc P, Ramirez-Weber FA, Laget MP, Schwartz C, Kornberg TB (1997)
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein
to the nucleus and converts it to a repressor. Cell 89:1043-1053
Bellaiche Y, The I, Perrimon N (1998) Tout-velu is a Drosophila homologue of
the putative tumour suppressor EXT-I and is needed for Hh diffusion. Nature 394:85-88
Belloni E, Muenke M, Roessler E, Traverso G, Siegel-Bartelt J, Frumkin A,
Mitchell HF, Donis-Keller H, Helms C, Hing AV, Heng HH, Koop B,
·Martindale D, Rommens JM, Tsui LC, Scherer SW (1996) Identification of
Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat
Genet 14:353-356
Bitgood MJ, Shen L, McMahon AP (1996) Sertoli cell signaling by Desert
hedgehog regulates the male germline. Curr BioI 6:298-304
Bumcrot DA, Takada R, McMahon AP (1995) Proteolytic processing yields
two secreted forms of sonic hedgehog. Mol Cell BioI 15:2294-2303
Capdevila J, Pariente F, Sampedro J, Alonso JL, Guerrero I (1994) Subcellular
localization of the segment polarity protein patched suggests an interaction
with the wingless reception complex in Drosophila embryos. Development
120:987-998
Carpenter D, Stone DM, Brush J, Ryan A, Arrnanini M, Frantz G, Rosenthal
A, de Sauvage FJ (1998) Characterization of two patched receptors for the
vertebrate hedgehog protein family. Proc Nat! Acad Sci USA
95: 13630-13634
References
Ahn J, Ludecke HJ, Lindow S, Horton WA, Lee B, Wagner MJ, Horsthemke
B, Wells DE (1995) Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXTl). Nat Genet 11: 137-143
Akimaru H, Chen Y, Dai P, Hou DX, Nonaka M, Smolik SM, Armstrong S,
Goodman RH, Ishii S (1997) Drosophila CBP is a co-activator of cubitus
interruptus in hedgehog signalling. Nature 386:735-738
A1cedo J, Ayzenzon M, Von Ohlen T, Noll M, Hooper JE (1996) The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative
receptor for the hedgehog signal. Cell 86:221-232
Alves G, Limbourg-Bouchon B, Tricoire H, Brissard-Zahraoui J, Lamour-Isnard C, Busson D (1998) Modulation of hedgehog target gene expression
by the fused serine- threonine kinase in wing imaginal discs. Mech Dev
78:17-31
Aszterbaum M, Rothman A, Johnson RL, Fisher M, Xie J, Bonifas JM, Zhang
X, Scott MP, Epstein EH Jr (1998) Identification of mutations in the human
PATCHED gene in sporadic basal cell carcinomas and in patients with the
basal cell nevus syndrome. J Invest DermatolllO:885-888
Aza-Blanc P, Ramirez-Weber FA, Laget MP, Schwartz C, Kornberg TB (1997)
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein
to the nucleus and converts it to a repressor. Cell 89:1043-1053
Bellaiche Y, The I, Perrimon N (1998) Tout-velu is a Drosophila homologue of
the putative tumour suppressor EXT-I and is needed for Hh diffusion. Nature 394:85-88
Belloni E, Muenke M, Roessler E, Traverso G, Siegel-Bartelt J, Frumkin A,
Mitchell HF, Donis-Keller H, Helms C, Hing AV, Heng HH, Koop B,
·Martindale D, Rommens JM, Tsui LC, Scherer SW (1996) Identification of
Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat
Genet 14:353-356
Bitgood MJ, Shen L, McMahon AP (1996) Sertoli cell signaling by Desert
hedgehog regulates the male germline. Curr BioI 6:298-304
Bumcrot DA, Takada R, McMahon AP (1995) Proteolytic processing yields
two secreted forms of sonic hedgehog. Mol Cell BioI 15:2294-2303
Capdevila J, Pariente F, Sampedro J, Alonso JL, Guerrero I (1994) Subcellular
localization of the segment polarity protein patched suggests an interaction
with the wingless reception complex in Drosophila embryos. Development
120:987-998
Carpenter D, Stone DM, Brush J, Ryan A, Arrnanini M, Frantz G, Rosenthal
A, de Sauvage FJ (1998) Characterization of two patched receptors for the
vertebrate hedgehog protein family. Proc Nat! Acad Sci USA
95: 13630-13634