417
Newman DJ, Cragg GM (2004) Marine natural products and related compounds in clinical and
advances preclinical trials. J Nat Prod 67:1216–1238
Olas B, Wachowicz B, Nowak P, Stochmal A, Oleszek W, Glowacki R (2007) Comparative
studies of the antioxidant effects of naturally occurring resveratrol analogue trans-3,3′,5,5′tetrahydroxy-4′-methoxystilbene and resveratrol against oxidation and nitration of biomolecules in blood platelets. Cell Biol Toxicol 24:331–340
Oliver J, Burg D, Wilson B, McLaughlin J, Geahlen R (1994) Inhibition of mast cell Fc epsilon
R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol. J Biol
Chem 269:29697–29703
Pan MH, Chang YH, Tsai ML, Lai CS, Ho SY, Badmaev V, Ho CT (2008) Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. J Agric Food Chem 56(16):7502–7509
Paul B, Masih I, Deopujari J, Charpentier C (1999) Occurrence of resveratrol and pterostilbene in
age-old Darakchasava, an Ayurvedic medicine from India. J Ethnopharmacol 68:71–76
Perecko T, Jancinová V, Drábiková K, Nosál R, Harmatha J (2008) Structure efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.
Neuroendocrinol Lett 29:802–805
Pezet R, Cuenat P (1996) Resveratrol in wine: extraction from skin during fermentation and postfermentation standing of must from Gamay grapes. Am J Enol Vitic 47:287–290
Pozo-Guisado E, Lorenzo-Benayas MJ, Fernandez-Salguero PM (2004) Resveratrol modulates the
phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism:
relevance in cell proliferation. Int J Cancer 109:167–173
Rajasekharan S, Tuli SN (1976) Vijayasar, Pterocarpus marsupium, in the treatment of Madhumeha
(diabetes mellitus) – a clinical trial. J Res Educ Indian Med 11:9–14
Rimando AM, Suh N (2008) Biological/chemopreventive activity of stilbenes and their effect on
colon cancer. Planta Med 74:1635–1643
Rimando AM, Nagmani R, Feller D, Rand Yokoyama W (2005) Pterostilbene, a new agonist for
the peroxisome proliferator-activated receptor alphaisoform, lowers plasma lipoproteins and
cholesterol in hypercholesterol emic hamsters. J Agric Food Chem 53:3403–3407
Rocha GHI, Ambriz-Tututi M, Granados-Soto V (2008) Resveratrol: a natural compound with
pharmacological potential in neurodegenerative diseases. CNS Neurosci Ther 14:234–247
Roggero JP, Garcia PC (1995) Effects of ultraviolet irradiation on resveratrol and changes in resveratrol and several of its derivatives in the skins of ripening grapes. Sci Aliment 15:411–422
Roupe KA, Remsberg CM, Yánez JA, Davies NM (2006) Pharma-8 cometrics of stilbenes: seguing towards the clinic. Curr Clin Pharmacol 1:81–101
Rubiolo JA, Mithieux G, Vega FV (2008) Resveratrol protects primary rat hepatocytes against
oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of
antioxidant enzymes. Eur J Pharmacol 591:66–72
Schwartsmann G, Da Rocha AB, Mattei J, Lopes R (2003) Expert Opin Investig Drugs
12:1367–1383
Sehadri R (1984) Polyphenols of Pterocarpus and Dalbergia woods. Phytochemistry 11:881–898
Shankar S, Singh G, Srivastava RK (2007) Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential. Front Biosci 12:4839–4854
Siemann EH, Creasy LL (1992) Concentration of the phytoalexin resveratrol in wine. Am J Enol
Vitic 43:1
Shekar S, Mariappan S (2008) Traditionally fermented biomedicines, arishtas and asavas from
ayurveda. Indian J Tradit Knowl 7:548–546
Subbaramaiah K, Dannenberg AJ (2001) Resveratrol inhibits the expression of cyclooxygenase2 in mammary epithelial cells. Adv Exp Med Biol 492:147–157
Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H (1998) Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 273:21875–21882
17 Stilbenes and Their Derivatives in Traditional Medicine
Newman DJ, Cragg GM (2004) Marine natural products and related compounds in clinical and
advances preclinical trials. J Nat Prod 67:1216–1238
Olas B, Wachowicz B, Nowak P, Stochmal A, Oleszek W, Glowacki R (2007) Comparative
studies of the antioxidant effects of naturally occurring resveratrol analogue trans-3,3′,5,5′tetrahydroxy-4′-methoxystilbene and resveratrol against oxidation and nitration of biomolecules in blood platelets. Cell Biol Toxicol 24:331–340
Oliver J, Burg D, Wilson B, McLaughlin J, Geahlen R (1994) Inhibition of mast cell Fc epsilon
R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol. J Biol
Chem 269:29697–29703
Pan MH, Chang YH, Tsai ML, Lai CS, Ho SY, Badmaev V, Ho CT (2008) Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. J Agric Food Chem 56(16):7502–7509
Paul B, Masih I, Deopujari J, Charpentier C (1999) Occurrence of resveratrol and pterostilbene in
age-old Darakchasava, an Ayurvedic medicine from India. J Ethnopharmacol 68:71–76
Perecko T, Jancinová V, Drábiková K, Nosál R, Harmatha J (2008) Structure efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.
Neuroendocrinol Lett 29:802–805
Pezet R, Cuenat P (1996) Resveratrol in wine: extraction from skin during fermentation and postfermentation standing of must from Gamay grapes. Am J Enol Vitic 47:287–290
Pozo-Guisado E, Lorenzo-Benayas MJ, Fernandez-Salguero PM (2004) Resveratrol modulates the
phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism:
relevance in cell proliferation. Int J Cancer 109:167–173
Rajasekharan S, Tuli SN (1976) Vijayasar, Pterocarpus marsupium, in the treatment of Madhumeha
(diabetes mellitus) – a clinical trial. J Res Educ Indian Med 11:9–14
Rimando AM, Suh N (2008) Biological/chemopreventive activity of stilbenes and their effect on
colon cancer. Planta Med 74:1635–1643
Rimando AM, Nagmani R, Feller D, Rand Yokoyama W (2005) Pterostilbene, a new agonist for
the peroxisome proliferator-activated receptor alphaisoform, lowers plasma lipoproteins and
cholesterol in hypercholesterol emic hamsters. J Agric Food Chem 53:3403–3407
Rocha GHI, Ambriz-Tututi M, Granados-Soto V (2008) Resveratrol: a natural compound with
pharmacological potential in neurodegenerative diseases. CNS Neurosci Ther 14:234–247
Roggero JP, Garcia PC (1995) Effects of ultraviolet irradiation on resveratrol and changes in resveratrol and several of its derivatives in the skins of ripening grapes. Sci Aliment 15:411–422
Roupe KA, Remsberg CM, Yánez JA, Davies NM (2006) Pharma-8 cometrics of stilbenes: seguing towards the clinic. Curr Clin Pharmacol 1:81–101
Rubiolo JA, Mithieux G, Vega FV (2008) Resveratrol protects primary rat hepatocytes against
oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of
antioxidant enzymes. Eur J Pharmacol 591:66–72
Schwartsmann G, Da Rocha AB, Mattei J, Lopes R (2003) Expert Opin Investig Drugs
12:1367–1383
Sehadri R (1984) Polyphenols of Pterocarpus and Dalbergia woods. Phytochemistry 11:881–898
Shankar S, Singh G, Srivastava RK (2007) Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential. Front Biosci 12:4839–4854
Siemann EH, Creasy LL (1992) Concentration of the phytoalexin resveratrol in wine. Am J Enol
Vitic 43:1
Shekar S, Mariappan S (2008) Traditionally fermented biomedicines, arishtas and asavas from
ayurveda. Indian J Tradit Knowl 7:548–546
Subbaramaiah K, Dannenberg AJ (2001) Resveratrol inhibits the expression of cyclooxygenase2 in mammary epithelial cells. Adv Exp Med Biol 492:147–157
Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H (1998) Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 273:21875–21882
17 Stilbenes and Their Derivatives in Traditional Medicine
