378
McAuliffe O, Ryan MP, Ross RP, Hill C, Breeuwer P, Abee T (1998) Lacticin 3147, a broadspectrum bacteriocin which selectively dissipates the membrane potential. Appl Environ
Microbiol 64:439–445
McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP,
Sidman RL, Pasqualini R, Arap W (2013) Mechanism of action and initial evaluation of a
membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A
110:3477–3482
Mendez-Samperio P (2010) The human cathelicidin hCAP18/LL-37: a multifunctional peptide
involved in mycobacterial infections. Peptides 31:1791–1798
Miteva M, Andersson M, Karshikoff A, Otting G (1999) Molecular electroporation: a unifying
concept for the description of membrane pore formation by antibacterial peptides, exemplified
with NK-lysin. FEBS Lett 462:155–158
Mohanram H, Bhattacharjya S (2016) ‘Lollipop’-shaped helical structure of a hybrid antimicrobial peptide of temporin B-lipopolysaccharide binding motif and mapping cationic residues in
antibacterial activity. Biochim Biophys Acta 1860:1362–1372
Morvan A, Bachere E, Da Silva PP, Pimenta P, Mialhe E (1994) In vitro activity of the antimicrobial peptide magainin 1 against Bonamia ostreae, the intrahemocytic parasite of the flat oyster
Ostrea edulis. Mol Mar Biol Biotechnol 3:327–333
Mueller H, Fae KC, Magdorf K, Ganoza CA, Wahn U, Guhlich U, Feiterna-Sperling C, Kaufmann
SH (2011) Granulysin-expressing CD4+ T cells as candidate immune marker for tuberculosis
during childhood and adolescence. PLoS One 6:e29367
Ojha AK, Baughn AD, Sambandan D, Hsu T, Trivelli X, Guerardel Y, Alahari A, Kremer L, Jacobs
WR Jr, Hatfull GF (2008) Growth of Mycobacterium tuberculosis biofilms containing free
mycolic acids and harbouring drug-tolerant bacteria. Mol Microbiol 69:164–174
Okada M, Kita Y, Nakajima T, Kanamaru N, Hashimoto S, Nagasawa T, Kaneda Y, Yoshida S,
Nishida Y, Nakatani H, Takao K, Kishigami C, Nishimatsu S, Sekine Y, Inoue Y, Matsumoto
M, McMurray DN, De la Cruz EC, Tan EV, Abalos RM, Burgos JA, Saunderson P, Sakatani
M (2011) Novel therapeutic vaccine: granulysin and new DNA vaccine against Tuberculosis.
Human Vaccin 7(Suppl):60–67
Pazgier M, Hoover DM, Yang D, Lu W, Lubkowski J (2006) Human beta-defensins. Cell Mol Life
Sci 63:1294–1313
Pena SV, Krensky AM (1997) Granulysin, a new human cytolytic granule-associated protein with
possible involvement in cell-mediated cytotoxicity. Semin Immunol 9:117–125
Pitabut N, Sakurada S, Tanaka T, Ridruechai C, Tanuma J, Aoki T, Kantipong P, Piyaworawong
S, Kobayashi N, Dhepakson P, Yanai H, Yamada N, Oka S, Okada M, Khusmith S, Keicho N
(2013) Potential function of granulysin, other related effector molecules and lymphocyte subsets in patients with TB and HIV/TB co infection. Int J Med Sci 10:1003–1014
Pokorny A, Almeida PF (2005) Permeabilization of raft-containing lipid vesicles by delta-lysin: a
mechanism for cell sensitivity to cytotoxic peptides. Biochemistry 44:9538–9544
Pulido D, Torrent M, Andreu D, Nogues MV, Boix E (2013) Two human host defense ribonucleases against mycobacteria, the eosinophil cationic protein (RNase 3) and RNase 7. Antimicrob
Agents Chemother 57:3797–3805
Purdy GE, Niederweis M, Russell DG (2009) Decreased outer membrane permeability protects
mycobacteria from killing by ubiquitin-derived peptides. Mol Microbiol 73:844–857
Rivas-Santiago CE, Rivas-Santiago B, Leon DA, Castaneda-Delgado J, Hernandez Pando R
(2011) Induction of beta-defensins by l-isoleucine as novel immunotherapy in experimental
murine tuberculosis. Clin Exp Immunol 164:80–89
Samuchiwal SK, Tousif S, Singh DK, Kumar A, Ghosh A, Bhalla K, Prakash P, Kumar S,
Bhattacharyya M, Moodley P, Das G, Ranganathan A (2014) A peptide fragment from the
human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins
ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response.
BMC Infect Dis 14:355
S.M. Thayil and A.K. Kesavan
McAuliffe O, Ryan MP, Ross RP, Hill C, Breeuwer P, Abee T (1998) Lacticin 3147, a broadspectrum bacteriocin which selectively dissipates the membrane potential. Appl Environ
Microbiol 64:439–445
McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP,
Sidman RL, Pasqualini R, Arap W (2013) Mechanism of action and initial evaluation of a
membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A
110:3477–3482
Mendez-Samperio P (2010) The human cathelicidin hCAP18/LL-37: a multifunctional peptide
involved in mycobacterial infections. Peptides 31:1791–1798
Miteva M, Andersson M, Karshikoff A, Otting G (1999) Molecular electroporation: a unifying
concept for the description of membrane pore formation by antibacterial peptides, exemplified
with NK-lysin. FEBS Lett 462:155–158
Mohanram H, Bhattacharjya S (2016) ‘Lollipop’-shaped helical structure of a hybrid antimicrobial peptide of temporin B-lipopolysaccharide binding motif and mapping cationic residues in
antibacterial activity. Biochim Biophys Acta 1860:1362–1372
Morvan A, Bachere E, Da Silva PP, Pimenta P, Mialhe E (1994) In vitro activity of the antimicrobial peptide magainin 1 against Bonamia ostreae, the intrahemocytic parasite of the flat oyster
Ostrea edulis. Mol Mar Biol Biotechnol 3:327–333
Mueller H, Fae KC, Magdorf K, Ganoza CA, Wahn U, Guhlich U, Feiterna-Sperling C, Kaufmann
SH (2011) Granulysin-expressing CD4+ T cells as candidate immune marker for tuberculosis
during childhood and adolescence. PLoS One 6:e29367
Ojha AK, Baughn AD, Sambandan D, Hsu T, Trivelli X, Guerardel Y, Alahari A, Kremer L, Jacobs
WR Jr, Hatfull GF (2008) Growth of Mycobacterium tuberculosis biofilms containing free
mycolic acids and harbouring drug-tolerant bacteria. Mol Microbiol 69:164–174
Okada M, Kita Y, Nakajima T, Kanamaru N, Hashimoto S, Nagasawa T, Kaneda Y, Yoshida S,
Nishida Y, Nakatani H, Takao K, Kishigami C, Nishimatsu S, Sekine Y, Inoue Y, Matsumoto
M, McMurray DN, De la Cruz EC, Tan EV, Abalos RM, Burgos JA, Saunderson P, Sakatani
M (2011) Novel therapeutic vaccine: granulysin and new DNA vaccine against Tuberculosis.
Human Vaccin 7(Suppl):60–67
Pazgier M, Hoover DM, Yang D, Lu W, Lubkowski J (2006) Human beta-defensins. Cell Mol Life
Sci 63:1294–1313
Pena SV, Krensky AM (1997) Granulysin, a new human cytolytic granule-associated protein with
possible involvement in cell-mediated cytotoxicity. Semin Immunol 9:117–125
Pitabut N, Sakurada S, Tanaka T, Ridruechai C, Tanuma J, Aoki T, Kantipong P, Piyaworawong
S, Kobayashi N, Dhepakson P, Yanai H, Yamada N, Oka S, Okada M, Khusmith S, Keicho N
(2013) Potential function of granulysin, other related effector molecules and lymphocyte subsets in patients with TB and HIV/TB co infection. Int J Med Sci 10:1003–1014
Pokorny A, Almeida PF (2005) Permeabilization of raft-containing lipid vesicles by delta-lysin: a
mechanism for cell sensitivity to cytotoxic peptides. Biochemistry 44:9538–9544
Pulido D, Torrent M, Andreu D, Nogues MV, Boix E (2013) Two human host defense ribonucleases against mycobacteria, the eosinophil cationic protein (RNase 3) and RNase 7. Antimicrob
Agents Chemother 57:3797–3805
Purdy GE, Niederweis M, Russell DG (2009) Decreased outer membrane permeability protects
mycobacteria from killing by ubiquitin-derived peptides. Mol Microbiol 73:844–857
Rivas-Santiago CE, Rivas-Santiago B, Leon DA, Castaneda-Delgado J, Hernandez Pando R
(2011) Induction of beta-defensins by l-isoleucine as novel immunotherapy in experimental
murine tuberculosis. Clin Exp Immunol 164:80–89
Samuchiwal SK, Tousif S, Singh DK, Kumar A, Ghosh A, Bhalla K, Prakash P, Kumar S,
Bhattacharyya M, Moodley P, Das G, Ranganathan A (2014) A peptide fragment from the
human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins
ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response.
BMC Infect Dis 14:355
S.M. Thayil and A.K. Kesavan