379
Santos P, Gordillo A, Osses L, Salazar LM, Soto CY (2012) Effect of antimicrobial peptides on
ATPase activity and proton pumping in plasma membrane vesicles obtained from mycobacteria. Peptides 36:121–128
Sharma S, Verma I, Khuller GK (2000) Antibacterial activity of human neutrophil peptide-1 against
Mycobacterium tuberculosis H37Rv: in vitro and ex vivo study. Eur Respir J 16:112–117
Sharma S, Verma I, Khuller GK (2001) Therapeutic potential of human neutrophil peptide 1
against experimental tuberculosis. Antimicrob Agents Chemother 45:639–640
Shi J, Ross CR, Chengappa MM, Blecha F (1994) Identification of a proline-arginine-rich antibacterial peptide from neutrophils that is analogous to PR-39, an antibacterial peptide from the
small intestine. J Leukoc Biol 56:807–811
Shi J, Ross CR, Leto TL, Blecha F (1996) PR-39, a proline-rich antibacterial peptide that inhibits
phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox. Proc
Natl Acad Sci U S A 93:6014–6018
Silva JP, Goncalves C, Costa C, Sousa J, Silva-Gomes R, Castro AG, Pedrosa J, Appelberg R,
Gama FM (2016) Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel
for tuberculosis treatment. J Control Release 235:112–124
Sosunov V, Mischenko V, Eruslanov B, Svetoch E, Shakina Y, Stern N, Majorov K, Sorokoumova
G, Selishcheva A, Apt A (2007) Antimycobacterial activity of bacteriocins and their complexes
with liposomes. J Antimicrob Chemother 59:919–925
Stenger S, Hanson DA, Teitelbaum R, Dewan P, Niazi KR, Froelich CJ, Ganz T, Thoma-Uszynski
S, Melian A, Bogdan C, Porcelli SA, Bloom BR, Krensky AM, Modlin RL (1998) An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282:121–125
Toro JC, Hoffner S, Linde C, Andersson M, Andersson J, Grundstrom S (2006) Enhanced susceptibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides
correlates with a reduced fitness phenotype. Microbes Infect 8:1985–1993
Venge P, Bystrom J, Carlson M, Hakansson L, Karawacjzyk M, Peterson C, Seveus L, Trulson A
(1999) Eosinophil cationic protein (ECP): molecular and biological properties and the use of
ECP as a marker of eosinophil activation in disease. Clin Exp Allergy 29:1172–1186
Waghu FH, Gopi L, Barai RS, Ramteke P, Nizami B, Idicula-Thomas S (2014) CAMP: collection
of sequences and structures of antimicrobial peptides. Nucleic Acids Res 42:D1154–D1158
Wang G (2015) Improved methods for classification, prediction, and design of antimicrobial peptides. Methods Mol Biol 1268:43–66
Wang Z, Choice E, Kaspar A, Hanson D, Okada S, Lyu SC, Krensky AM, Clayberger C (2000)
Bactericidal and tumoricidal activities of synthetic peptides derived from granulysin. J Immunol
165:1486–1490
Wei L, Wu J, Liu H, Yang H, Rong M, Li D, Zhang P, Han J, Lai R (2013) A mycobacteriophagederived trehalose-6,6′-dimycolate-binding peptide containing both antimycobacterial and antiinflammatory abilities. FASEB J 27:3067–3077
Wenzel M, Chiriac AI, Otto A, Zweytick D, May C, Schumacher C, Gust R, Albada HB, Penkova
M, Kramer U, Erdmann R, Metzler-Nolte N, Straus SK, Bremer E, Becher D, Brotz-Oesterhelt
H, Sahl HG, Bandow JE (2014) Small cationic antimicrobial peptides delocalize peripheral
membrane proteins. Proc Natl Acad Sci U S A 111:E1409–E1418
World Health Organization (2013) Global tuberculosis report 2013: www.who.int/tb
World Health Organization (2015) Global tuberculosis report 2015: www.who.int/tb
Yeaman MR, Yount NY (2003) Mechanisms of antimicrobial peptide action and resistance.
Pharmacol Rev 55:27–55
Zasloff M (1987) Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad
Sci U S A 84:5449–5453
Zhang J, Dyer KD, Rosenberg HF (2003) Human RNase 7: a new cationic ribonuclease of the
RNase A superfamily. Nucleic Acids Res 31:602–607
Zhao X, Wu H, Lu H, Li G, Huang Q (2013) LAMP: a database linking antimicrobial peptides.
PLoS One 8:e66557
15 Antimycobacterial Peptides
Santos P, Gordillo A, Osses L, Salazar LM, Soto CY (2012) Effect of antimicrobial peptides on
ATPase activity and proton pumping in plasma membrane vesicles obtained from mycobacteria. Peptides 36:121–128
Sharma S, Verma I, Khuller GK (2000) Antibacterial activity of human neutrophil peptide-1 against
Mycobacterium tuberculosis H37Rv: in vitro and ex vivo study. Eur Respir J 16:112–117
Sharma S, Verma I, Khuller GK (2001) Therapeutic potential of human neutrophil peptide 1
against experimental tuberculosis. Antimicrob Agents Chemother 45:639–640
Shi J, Ross CR, Chengappa MM, Blecha F (1994) Identification of a proline-arginine-rich antibacterial peptide from neutrophils that is analogous to PR-39, an antibacterial peptide from the
small intestine. J Leukoc Biol 56:807–811
Shi J, Ross CR, Leto TL, Blecha F (1996) PR-39, a proline-rich antibacterial peptide that inhibits
phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox. Proc
Natl Acad Sci U S A 93:6014–6018
Silva JP, Goncalves C, Costa C, Sousa J, Silva-Gomes R, Castro AG, Pedrosa J, Appelberg R,
Gama FM (2016) Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel
for tuberculosis treatment. J Control Release 235:112–124
Sosunov V, Mischenko V, Eruslanov B, Svetoch E, Shakina Y, Stern N, Majorov K, Sorokoumova
G, Selishcheva A, Apt A (2007) Antimycobacterial activity of bacteriocins and their complexes
with liposomes. J Antimicrob Chemother 59:919–925
Stenger S, Hanson DA, Teitelbaum R, Dewan P, Niazi KR, Froelich CJ, Ganz T, Thoma-Uszynski
S, Melian A, Bogdan C, Porcelli SA, Bloom BR, Krensky AM, Modlin RL (1998) An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282:121–125
Toro JC, Hoffner S, Linde C, Andersson M, Andersson J, Grundstrom S (2006) Enhanced susceptibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides
correlates with a reduced fitness phenotype. Microbes Infect 8:1985–1993
Venge P, Bystrom J, Carlson M, Hakansson L, Karawacjzyk M, Peterson C, Seveus L, Trulson A
(1999) Eosinophil cationic protein (ECP): molecular and biological properties and the use of
ECP as a marker of eosinophil activation in disease. Clin Exp Allergy 29:1172–1186
Waghu FH, Gopi L, Barai RS, Ramteke P, Nizami B, Idicula-Thomas S (2014) CAMP: collection
of sequences and structures of antimicrobial peptides. Nucleic Acids Res 42:D1154–D1158
Wang G (2015) Improved methods for classification, prediction, and design of antimicrobial peptides. Methods Mol Biol 1268:43–66
Wang Z, Choice E, Kaspar A, Hanson D, Okada S, Lyu SC, Krensky AM, Clayberger C (2000)
Bactericidal and tumoricidal activities of synthetic peptides derived from granulysin. J Immunol
165:1486–1490
Wei L, Wu J, Liu H, Yang H, Rong M, Li D, Zhang P, Han J, Lai R (2013) A mycobacteriophagederived trehalose-6,6′-dimycolate-binding peptide containing both antimycobacterial and antiinflammatory abilities. FASEB J 27:3067–3077
Wenzel M, Chiriac AI, Otto A, Zweytick D, May C, Schumacher C, Gust R, Albada HB, Penkova
M, Kramer U, Erdmann R, Metzler-Nolte N, Straus SK, Bremer E, Becher D, Brotz-Oesterhelt
H, Sahl HG, Bandow JE (2014) Small cationic antimicrobial peptides delocalize peripheral
membrane proteins. Proc Natl Acad Sci U S A 111:E1409–E1418
World Health Organization (2013) Global tuberculosis report 2013: www.who.int/tb
World Health Organization (2015) Global tuberculosis report 2015: www.who.int/tb
Yeaman MR, Yount NY (2003) Mechanisms of antimicrobial peptide action and resistance.
Pharmacol Rev 55:27–55
Zasloff M (1987) Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad
Sci U S A 84:5449–5453
Zhang J, Dyer KD, Rosenberg HF (2003) Human RNase 7: a new cationic ribonuclease of the
RNase A superfamily. Nucleic Acids Res 31:602–607
Zhao X, Wu H, Lu H, Li G, Huang Q (2013) LAMP: a database linking antimicrobial peptides.
PLoS One 8:e66557
15 Antimycobacterial Peptides