361
Adonizio A, Dawlaty J, Ausubel FM, Clardy J, Mathee K (2008) Ellagitannins from Conocarpus
erectus exhibit anti-quorum sensing activity against Pseudomonas aeruginosa. Planta Med
74:1035–1035
Amaya S, Pereira JA, Borkosky SA, Valdez JC, Bardon A, Arena ME (2012) Inhibition of quorum
sensing in Pseudomonas aeruginosa by sesquiterpene lactones. Phytomedicine 19:1173–1177
Anderson JC, Clarke EJ, Arkin AP, Voigt CA (2006) Environmentally controlled invasion of cancer cells by engineered bacteria. J Mol Biol 355:619–627
Bassler BL, Wright M, Showalter RE, Silverman MR (1993) Intercellular signalling in Vibrio
harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol
9:773–786. doi:10.1111/j.1365-2958.1993.tb01737.x
Bassler BL, Wright M, Silverman MR (1994) Multiple signalling systems controlling expression
of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory
pathway. Mol Microbiol 13:273–286. doi:10.1111/j.1365-2958.1994.tb00422.x
Bhargava N, Sharma P, Capalash N (2010) Quorum sensing in Acinetobacter: an emerging pathogen. Crit Rev Microbiol 36:349–360
Brackman G, Celen S, Hillaert U, van Calenbergh S, Cos P, Maes L, Nelis HJ, Coenye T (2011)
Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum
sensing and their effect on virulence of vibrio spp. PLoS One 6:e16084
Chowdhary PK, Keshavan N, Nguyen HQ, Peterson JA, Gonzales JE, Haines DC (2007)
Biochemistry 46:14429–14437
Clark BR, Engene N, Teasdale ME, Rowley DC, Matainaho T, Valeriote FA, Gerwick WH (2008)
Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum. J Nat Prod 71:1530–1537
Cugini C, Calfee MW, Farrow JM, Morales DK, Pesci EC, Hogan DA (2007) Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. Mol Microbiol
65:896–906
Davis TH (2004) Biography of E.P. Greenberg. Proc Natl Acad Sci U S A 101(45):15830–15832.
http://doi.org/10.1073/pnas.0407738101
Defoirdt T, Brackman G, Coenye T (2013) Quorum sensing inhibitors: how strong is the evidence?
Trends Microbiol 21(12):619–624
Defoirdt T, Miyamoto CM, Wood TK, Meighen EA, Sorgeloos P, Verstraete W, Bossier P (2007)
The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts
quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding
activity of the transcriptional regulator protein luxR. Environ Microbiol 9:2486–2495
Defoirdt T, Crab R, Wood TK, Sorgeloos P, Verstraete W, Bossier P (2006) Quorum sensingdisrupting brominated furanones protect the gnotobiotic brine shrimp Artemia franciscana
from pathogenic Vibrio harveyi, Vibrio campbellii, and Vibrio parahaemolyticus isolates. Appl
Environ Microbiol 72:6419–6423
Dobretsov S, Teplitski M, Alagely A, Gunasekera SP, Paul VJ (2010) Malyngolide from the cyanobacterium Lyngbya majuscula interferes with quorum sensing circuitry. Environ Microbiol
Rep 2:739–744
Dong YH, Wang LH, Xu JL, Zhang HB, Zhang XF, Zhang LH (2001) Quenching quorum-sensingdependent bacterial infection by an N-acyl homoserine lactonase. Nature 411:813–817
Dong Y, Wang LH, Zhang LH (2007) Quorum-quenching microbial infections: mechanisms and
implications. Philos Trans R Soc Lond Ser B Biol Sci 362:1201–1211
Duncan MC, Wong WR, Dupzyk AJ, Bray WM, Linington RG, Auerbuch V (2014) An
NF-kappaB-based high-throughput screen identifies piericidins as inhibitors of the Yersinia
pseudotuberculosis type III secretion system. Antimicrob Agents Chemother 58:1118–1126
Fuqua WC, Winans SC, Greenberg EP (1994) Quorum sensing in bacteria: the LuxR-LuxI family
of cell density-responsive transcriptional regulators. J Bacteriol 176:269–275
García-Contreras R, Martínez-Vázquez M, Velázquez Guadarrama N, Villegas Pañeda AG,
Hashimoto T, Maeda T, Wood TK (2013) Resistance to the quorum-quenching compounds
14 Quorum Quenching Compounds from Natural Sources
Adonizio A, Dawlaty J, Ausubel FM, Clardy J, Mathee K (2008) Ellagitannins from Conocarpus
erectus exhibit anti-quorum sensing activity against Pseudomonas aeruginosa. Planta Med
74:1035–1035
Amaya S, Pereira JA, Borkosky SA, Valdez JC, Bardon A, Arena ME (2012) Inhibition of quorum
sensing in Pseudomonas aeruginosa by sesquiterpene lactones. Phytomedicine 19:1173–1177
Anderson JC, Clarke EJ, Arkin AP, Voigt CA (2006) Environmentally controlled invasion of cancer cells by engineered bacteria. J Mol Biol 355:619–627
Bassler BL, Wright M, Showalter RE, Silverman MR (1993) Intercellular signalling in Vibrio
harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol
9:773–786. doi:10.1111/j.1365-2958.1993.tb01737.x
Bassler BL, Wright M, Silverman MR (1994) Multiple signalling systems controlling expression
of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory
pathway. Mol Microbiol 13:273–286. doi:10.1111/j.1365-2958.1994.tb00422.x
Bhargava N, Sharma P, Capalash N (2010) Quorum sensing in Acinetobacter: an emerging pathogen. Crit Rev Microbiol 36:349–360
Brackman G, Celen S, Hillaert U, van Calenbergh S, Cos P, Maes L, Nelis HJ, Coenye T (2011)
Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum
sensing and their effect on virulence of vibrio spp. PLoS One 6:e16084
Chowdhary PK, Keshavan N, Nguyen HQ, Peterson JA, Gonzales JE, Haines DC (2007)
Biochemistry 46:14429–14437
Clark BR, Engene N, Teasdale ME, Rowley DC, Matainaho T, Valeriote FA, Gerwick WH (2008)
Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum. J Nat Prod 71:1530–1537
Cugini C, Calfee MW, Farrow JM, Morales DK, Pesci EC, Hogan DA (2007) Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. Mol Microbiol
65:896–906
Davis TH (2004) Biography of E.P. Greenberg. Proc Natl Acad Sci U S A 101(45):15830–15832.
http://doi.org/10.1073/pnas.0407738101
Defoirdt T, Brackman G, Coenye T (2013) Quorum sensing inhibitors: how strong is the evidence?
Trends Microbiol 21(12):619–624
Defoirdt T, Miyamoto CM, Wood TK, Meighen EA, Sorgeloos P, Verstraete W, Bossier P (2007)
The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts
quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding
activity of the transcriptional regulator protein luxR. Environ Microbiol 9:2486–2495
Defoirdt T, Crab R, Wood TK, Sorgeloos P, Verstraete W, Bossier P (2006) Quorum sensingdisrupting brominated furanones protect the gnotobiotic brine shrimp Artemia franciscana
from pathogenic Vibrio harveyi, Vibrio campbellii, and Vibrio parahaemolyticus isolates. Appl
Environ Microbiol 72:6419–6423
Dobretsov S, Teplitski M, Alagely A, Gunasekera SP, Paul VJ (2010) Malyngolide from the cyanobacterium Lyngbya majuscula interferes with quorum sensing circuitry. Environ Microbiol
Rep 2:739–744
Dong YH, Wang LH, Xu JL, Zhang HB, Zhang XF, Zhang LH (2001) Quenching quorum-sensingdependent bacterial infection by an N-acyl homoserine lactonase. Nature 411:813–817
Dong Y, Wang LH, Zhang LH (2007) Quorum-quenching microbial infections: mechanisms and
implications. Philos Trans R Soc Lond Ser B Biol Sci 362:1201–1211
Duncan MC, Wong WR, Dupzyk AJ, Bray WM, Linington RG, Auerbuch V (2014) An
NF-kappaB-based high-throughput screen identifies piericidins as inhibitors of the Yersinia
pseudotuberculosis type III secretion system. Antimicrob Agents Chemother 58:1118–1126
Fuqua WC, Winans SC, Greenberg EP (1994) Quorum sensing in bacteria: the LuxR-LuxI family
of cell density-responsive transcriptional regulators. J Bacteriol 176:269–275
García-Contreras R, Martínez-Vázquez M, Velázquez Guadarrama N, Villegas Pañeda AG,
Hashimoto T, Maeda T, Wood TK (2013) Resistance to the quorum-quenching compounds
14 Quorum Quenching Compounds from Natural Sources