362
brominated furanone C-30 and 5-fluorouracil in Pseudomonas aeruginosa clinical isolates.
Pathogens Dis 68(1):8–11. http://doi.org/10.1111/2049-632X.12039
Giménez-Bastida JA, Truchado P, Larrosa M, Espín JC, Tomás-Barberán FA, Allende A, GarcíaConesa MT (2012) Urolithins, ellagitannin metabolites produced by colon microbiota, inhibit
quorum sensing in Yersinia enterocolitica: phenotypic response and associated molecular
changes. Food Chem 132:1465–1474
Golberg K, Pavlov V, Marks RS, Kushmaro A (2013) Coral-associated bacteria, quorum sensing
disrupters, and the regulation of biofouling. Biofouling 29:669–682
González JE, Keshavan ND (2006) Messing with bacterial quorum sensing. Microbiol Mol Biol
Rev 70:859–875
Hanson JR (2003) The classes of natural product and their isolation. In: Abel EW (ed) Natural
products: the secondary metabolites. Royal Society of Chemistry, Cambridge, pp 1–34
Havsteen BH (2002) The biochemistry and medical significance of the flavonoids. Pharmacol Ther
96:67–202
Henke J, Bassler B (2004) Bacterial social engagements. Trends Cell Biol 14(11):648–656
Hentzer M, Givskov M (2003) Pharmacological inhibition of quorum sensing for the treatment of
chronic bacterial infections. J Clin Invest 112(9):1300–1307
Imperi F, Massai F, Ramachandran Pillai C, Longo F, Zennaro E, Rampioni G, Visca P, Leoni
L (2013) New life for an old drug: the anthelmintic drug niclosamide inhibits Pseudomonas
aeruginosa quorum sensing. Antimicrob Agents Chemother 57:996–1005
Jakobsen TH, van Gennip M, Phipps RK, Shanmugham MS, Christensen LD, Alhede M,
Skindersoe ME, Rasmussen TB, Friedrich K, Uthe F et al (2012) Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother
56:2314–2325
Kaufmann GF, Sartorio R, Lee SH, Mee JM, Altobell LJ, Kujawa DP, Jeffries E, Clapham B,
Meijler MM, Janda KD (2006) Antibody interference with N-acyl homoserine lactonemediated bacterial quorum sensing. J Am Chem Soc 128(9):2802–2803
Kaufmann GF, Park J, Mee JM, Ulevitch RJ, Janda KD (2008) The quorum quenching antibody
RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa
quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone. Mol Immunol
45:2710–2714
Kiran MD, Adikesavan NV, Cirioni O, Giacometti A, Silvestri C, Scalise G, Ghiselli R, Saba V,
Orlando F, Shoham M et al (2008) Discovery of a quorum-sensing inhibitor of drug-resistant
staphylococcal infections by structure-based virtual screening. Mol Pharmacol 73:1578–1586
Kjelleberg S, Steinberg P, Givskov M, Gram L, Manefield M, de Nys R (1997) Do marine natural
products interfere with prokaryotic AHL regulatory systems? Aquat Microb Ecol 13:8
Koh CL, Sam CK, Yin WF, Tan L, Krishnan T, Chong Y, Chan KG (2013) Plant-derived natural
products as sources of anti-quorum sensing compounds. Sensors 13(5):6217–6228
Lade H, Paul D, Kweon JH (2014) Quorum quenching mediated approaches for control of membrane biofouling. Int J Biol Sci 10(5):547–562. http://doi.org/10.7150/ijbs.9028
LaSarre B, Federle MJ (2013) Exploiting quorum sensing to confuse bacterial pathogens.
Microbiol Mol Biol Rev 77:73–111
Lazazzera BA, Grossman AD (1998) The ins and outs of peptide signaling. Trends Microbiol
6(7):288–294
Leadbetter JR, Greenberg EP (2000) Metabolism of acyl-homoserine lactone quorum-sensing signals by Variovorax paradoxus. J Bacteriol 182:6921–6926
Lesic B, Lepine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S,
Tzika AA, Tompkins RG, Rahme LG (2007) Inhibitors of pathogen intercellular signals as
selective anti-infective compounds. PLoS Pathog 3:e126. doi:10.1371/journal.ppat.0030126
Li J, Wang W, Xu SX, Magarvey NA, McCormick JK (2011) Lactobacillus reuteri-produced cyclic
dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci.
Proc Natl Acad Sci U S A 108:3360–3365
G. Seghal Kiran et al.
brominated furanone C-30 and 5-fluorouracil in Pseudomonas aeruginosa clinical isolates.
Pathogens Dis 68(1):8–11. http://doi.org/10.1111/2049-632X.12039
Giménez-Bastida JA, Truchado P, Larrosa M, Espín JC, Tomás-Barberán FA, Allende A, GarcíaConesa MT (2012) Urolithins, ellagitannin metabolites produced by colon microbiota, inhibit
quorum sensing in Yersinia enterocolitica: phenotypic response and associated molecular
changes. Food Chem 132:1465–1474
Golberg K, Pavlov V, Marks RS, Kushmaro A (2013) Coral-associated bacteria, quorum sensing
disrupters, and the regulation of biofouling. Biofouling 29:669–682
González JE, Keshavan ND (2006) Messing with bacterial quorum sensing. Microbiol Mol Biol
Rev 70:859–875
Hanson JR (2003) The classes of natural product and their isolation. In: Abel EW (ed) Natural
products: the secondary metabolites. Royal Society of Chemistry, Cambridge, pp 1–34
Havsteen BH (2002) The biochemistry and medical significance of the flavonoids. Pharmacol Ther
96:67–202
Henke J, Bassler B (2004) Bacterial social engagements. Trends Cell Biol 14(11):648–656
Hentzer M, Givskov M (2003) Pharmacological inhibition of quorum sensing for the treatment of
chronic bacterial infections. J Clin Invest 112(9):1300–1307
Imperi F, Massai F, Ramachandran Pillai C, Longo F, Zennaro E, Rampioni G, Visca P, Leoni
L (2013) New life for an old drug: the anthelmintic drug niclosamide inhibits Pseudomonas
aeruginosa quorum sensing. Antimicrob Agents Chemother 57:996–1005
Jakobsen TH, van Gennip M, Phipps RK, Shanmugham MS, Christensen LD, Alhede M,
Skindersoe ME, Rasmussen TB, Friedrich K, Uthe F et al (2012) Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother
56:2314–2325
Kaufmann GF, Sartorio R, Lee SH, Mee JM, Altobell LJ, Kujawa DP, Jeffries E, Clapham B,
Meijler MM, Janda KD (2006) Antibody interference with N-acyl homoserine lactonemediated bacterial quorum sensing. J Am Chem Soc 128(9):2802–2803
Kaufmann GF, Park J, Mee JM, Ulevitch RJ, Janda KD (2008) The quorum quenching antibody
RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa
quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone. Mol Immunol
45:2710–2714
Kiran MD, Adikesavan NV, Cirioni O, Giacometti A, Silvestri C, Scalise G, Ghiselli R, Saba V,
Orlando F, Shoham M et al (2008) Discovery of a quorum-sensing inhibitor of drug-resistant
staphylococcal infections by structure-based virtual screening. Mol Pharmacol 73:1578–1586
Kjelleberg S, Steinberg P, Givskov M, Gram L, Manefield M, de Nys R (1997) Do marine natural
products interfere with prokaryotic AHL regulatory systems? Aquat Microb Ecol 13:8
Koh CL, Sam CK, Yin WF, Tan L, Krishnan T, Chong Y, Chan KG (2013) Plant-derived natural
products as sources of anti-quorum sensing compounds. Sensors 13(5):6217–6228
Lade H, Paul D, Kweon JH (2014) Quorum quenching mediated approaches for control of membrane biofouling. Int J Biol Sci 10(5):547–562. http://doi.org/10.7150/ijbs.9028
LaSarre B, Federle MJ (2013) Exploiting quorum sensing to confuse bacterial pathogens.
Microbiol Mol Biol Rev 77:73–111
Lazazzera BA, Grossman AD (1998) The ins and outs of peptide signaling. Trends Microbiol
6(7):288–294
Leadbetter JR, Greenberg EP (2000) Metabolism of acyl-homoserine lactone quorum-sensing signals by Variovorax paradoxus. J Bacteriol 182:6921–6926
Lesic B, Lepine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S,
Tzika AA, Tompkins RG, Rahme LG (2007) Inhibitors of pathogen intercellular signals as
selective anti-infective compounds. PLoS Pathog 3:e126. doi:10.1371/journal.ppat.0030126
Li J, Wang W, Xu SX, Magarvey NA, McCormick JK (2011) Lactobacillus reuteri-produced cyclic
dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci.
Proc Natl Acad Sci U S A 108:3360–3365
G. Seghal Kiran et al.