40. De Vos WM, Kuipers OP, van der Meer JR, Siezen RJ (1995b) Maturation pathway of nisin
and other lantibiotics: post-translational modified antimicrobial peptides exported by
Gram-positive bacteria. Mol Microbiol 17 : 427–437
41. Havarstein LS, Holo H, Nes IF (1994) The leader peptide of colicin V shares consensus
sequences with leader peptides that are common among peptide bacteriocins produced
by gram positive bacteria. Microbiology 140 : 2383–2389
42. Hastings JW, Sailer M, Johnson K, Rou KK,Vederas JC, Stiles ME (1991) Characterization
of leucocin A UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum. J
Bacteriol 173 : 7491–7500
43. Holck A, Axelsson L, Birkeland S-E, Aukrust T, Blom H (1992) Purification and amino
acid sequence of sakacin A, a bacteriocin from Lactobacillus sake Lb706. J Gen Microbiol
138 : 2715–2720
44. Lozano JCN, Meyer JN, Sletten K, Pelaz C, Nes IF (1992) Purification and amino acid
sequence of a bacteriocin produced by Pedicococcus acidilactici. J Gen Microbiol 138:
1985–1990
45. Tichaczek PS, Nissen-Meyer J, Nes IF, Vogel RF, Hammes WP (1992) Characterization of
the bacteriocin curvacin A from Lactobacillus curvatus LTH 1174 and sakacin P from
L. sake LTH673. Syst Appl Microbiol 15 : 460–468
46. van Belkum MJ, Hayema BJ, Jeeninga RE, Kok J, Venema G (1991a) Organization and
nucleotide sequence of two lactococcal bacteriocin operons. Appl Environ Microbiol
57 : 492–498
47. Nissen-Meyer J, Holo H, Håvarstein LS, Sletten K, Nes IF (1992) A novel lactococcal
bacteriocin whose activity depends on the complementary action of two peptides. J
Bacteriol 174 : 5686–5692
48. Allison GE, Frémaux C, Klaenhammer TR (1994) Expansion of bacteriocin activity and
host range upon complementation of two peptides encoded within the lactacin F
operon. J Bacteriol 176 : 2235–2241
49. Diep DB, Håvarstein LS, Nes IF (1996) Characterization of the locus responsible for the
bacteriocin production in Lactobacillus plantarum Cll. J Bacteriol 178 : 4472–4483
50. Leer RL, van der Vossen JMBM, van Giezen M, van Noort JM, Pouwels PH (1995) Genetic
analysis of acidocin B, a novel bacteriocin produced by lactobacillus acidophilus.
Microbiology 141:1629–1635
51. Worobo RW, van Belkum MJ, Sailer M, Roy KL, Vederas JC, Stiles ME (1995) A signal
peptide-dependent bacteriocin from Carnobacterium divergens. J Bacteriol 177 : 3143–
3149
52. Metha AM, Patel KA, Dave PJ (1983) Isolation and purification of an inhibitory protein
from Lactobacillus acidophilus ACT. Microbiology 37 : 37–43
53. Joerger MC, Klaenhammer TR (1986) Characterization and purification of helveticin J
and evidence for a chromosomally determined, bacteriocin produced by Lactobacillus
helveticus 481. J Bacteriol 167 : 439–446
54. Joerger MC, Klaenhammer TR (1990) Cloning, expression and nucleotide sequence of
the Lactobacillus helveticus 481 gene encoding the bacteriocin helveticin J JBacteriol
172 : 6339–6347
55. Toba T, Yoshioka E, Itoh T (1991) Acidophilucin A, a new heat-labile bacteriocin produced by Lactobacillus acidophilus LAPT 1060. Lett Appl Microbiol 12 :106–108
56. Vaughan EE, Daly C, Fitzgerald GF (1992) Identification and characterization of
helveticin V-1829, a bacteriocin produced by Lactobacillus helveticus 1829. J Appl
Bacteriol 73 : 299–308
57. Upreti GC, Hinsdill RD (1973) Isolation and characterization of a bacteriocin from a
homofermentative Lactobacillus. Antimicrob Agents Chemother 4 : 487–494
58. Upreti GC, Hinsdill RD (1975a) Isolation and characterization of a bacteriocin from a
homofermentative Lactobacillus. Antimicrob Agents Chemother 7 :139–145
59. Lewus CB, Sun S, Montville TJ (1992) Production of an amylase-sensitive bacteriocin
by an atypical Leuconostoc paramesenteroides strain. Appl Environ Microbiol 58 :
143–149
52
E. Sablon et al.
and other lantibiotics: post-translational modified antimicrobial peptides exported by
Gram-positive bacteria. Mol Microbiol 17 : 427–437
41. Havarstein LS, Holo H, Nes IF (1994) The leader peptide of colicin V shares consensus
sequences with leader peptides that are common among peptide bacteriocins produced
by gram positive bacteria. Microbiology 140 : 2383–2389
42. Hastings JW, Sailer M, Johnson K, Rou KK,Vederas JC, Stiles ME (1991) Characterization
of leucocin A UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum. J
Bacteriol 173 : 7491–7500
43. Holck A, Axelsson L, Birkeland S-E, Aukrust T, Blom H (1992) Purification and amino
acid sequence of sakacin A, a bacteriocin from Lactobacillus sake Lb706. J Gen Microbiol
138 : 2715–2720
44. Lozano JCN, Meyer JN, Sletten K, Pelaz C, Nes IF (1992) Purification and amino acid
sequence of a bacteriocin produced by Pedicococcus acidilactici. J Gen Microbiol 138:
1985–1990
45. Tichaczek PS, Nissen-Meyer J, Nes IF, Vogel RF, Hammes WP (1992) Characterization of
the bacteriocin curvacin A from Lactobacillus curvatus LTH 1174 and sakacin P from
L. sake LTH673. Syst Appl Microbiol 15 : 460–468
46. van Belkum MJ, Hayema BJ, Jeeninga RE, Kok J, Venema G (1991a) Organization and
nucleotide sequence of two lactococcal bacteriocin operons. Appl Environ Microbiol
57 : 492–498
47. Nissen-Meyer J, Holo H, Håvarstein LS, Sletten K, Nes IF (1992) A novel lactococcal
bacteriocin whose activity depends on the complementary action of two peptides. J
Bacteriol 174 : 5686–5692
48. Allison GE, Frémaux C, Klaenhammer TR (1994) Expansion of bacteriocin activity and
host range upon complementation of two peptides encoded within the lactacin F
operon. J Bacteriol 176 : 2235–2241
49. Diep DB, Håvarstein LS, Nes IF (1996) Characterization of the locus responsible for the
bacteriocin production in Lactobacillus plantarum Cll. J Bacteriol 178 : 4472–4483
50. Leer RL, van der Vossen JMBM, van Giezen M, van Noort JM, Pouwels PH (1995) Genetic
analysis of acidocin B, a novel bacteriocin produced by lactobacillus acidophilus.
Microbiology 141:1629–1635
51. Worobo RW, van Belkum MJ, Sailer M, Roy KL, Vederas JC, Stiles ME (1995) A signal
peptide-dependent bacteriocin from Carnobacterium divergens. J Bacteriol 177 : 3143–
3149
52. Metha AM, Patel KA, Dave PJ (1983) Isolation and purification of an inhibitory protein
from Lactobacillus acidophilus ACT. Microbiology 37 : 37–43
53. Joerger MC, Klaenhammer TR (1986) Characterization and purification of helveticin J
and evidence for a chromosomally determined, bacteriocin produced by Lactobacillus
helveticus 481. J Bacteriol 167 : 439–446
54. Joerger MC, Klaenhammer TR (1990) Cloning, expression and nucleotide sequence of
the Lactobacillus helveticus 481 gene encoding the bacteriocin helveticin J JBacteriol
172 : 6339–6347
55. Toba T, Yoshioka E, Itoh T (1991) Acidophilucin A, a new heat-labile bacteriocin produced by Lactobacillus acidophilus LAPT 1060. Lett Appl Microbiol 12 :106–108
56. Vaughan EE, Daly C, Fitzgerald GF (1992) Identification and characterization of
helveticin V-1829, a bacteriocin produced by Lactobacillus helveticus 1829. J Appl
Bacteriol 73 : 299–308
57. Upreti GC, Hinsdill RD (1973) Isolation and characterization of a bacteriocin from a
homofermentative Lactobacillus. Antimicrob Agents Chemother 4 : 487–494
58. Upreti GC, Hinsdill RD (1975a) Isolation and characterization of a bacteriocin from a
homofermentative Lactobacillus. Antimicrob Agents Chemother 7 :139–145
59. Lewus CB, Sun S, Montville TJ (1992) Production of an amylase-sensitive bacteriocin
by an atypical Leuconostoc paramesenteroides strain. Appl Environ Microbiol 58 :
143–149
52
E. Sablon et al.