Subject Index
- structure/function 289-292
- TIMPs, biomolecular interaction 292-298
metastasis 290
methylation 177
MHC 336
microcrystals 235-237
micro globulin 336
microsequence analysis 84
mirystoyl-group 313
monosaccharide 324, 341, 342, 346, 360, 361
morphiceptin 201
mouse 241
M -state, trapping 230-234
mucins 341
mucoproteins 341
mucorpepsin 185
multiple sclerosis 289
mutant, tumorgenetic p53 257
N
neutron diffraction 229
Newcastle disease virus (NOV) 124-127
NMR 91,201,248,321
- bimolecular 91
- chemical shift/exchange 95-97, 112
- criteria 93
- dipolar coupling
- - constants 102
- - residual 103, 104
- experimental conditions 92
- high-resolution 92
- hydrogen exchange rate constants 101, 102
- isotopic labelling 94
isotropic rotational diffusion 102, 103
nuclear Overhauser-effect 99
- protein, buffers 92
- relaxation 98
- - cross-correlated relaxation rate constant
101
- - heteronuclear relaxation rate constant 99,
100
- sample preparation 93
- scalar coupling constants 97, 98
structure determination 105-107
- spectral parameters 94, 95
- spectrometer 101, 200
- size of protein 93
- TROSY 101
- two-dimensional 91
N-terminal group 185,264
- blocking 177
- desalting 177
nuclear antigen 120
nucleic acid 143, 341, 352
- reverse stammg 30
nucleoprotein 264, 267
nucleoptide, probes 24
o
oligonucleotide probe 66
oligopeptide 202
oligosaccharide 321,325,331,341,343
- analysis of structure 133-135, 248, 249,
322-324
O-linked 151
- sequencing 322
- I)-oligosaccharide 361
- glycosic linkage 347
oncogene 257
osteoarthrosis 350
osteoarthritis 289, 290, 322
Overhauser-effect, nuclear 99
oxopeptide 208
P
p53 complex, structural model 257-270
- co-crystal-structure 260, 261
DNA twisting/bending 264-267
- function, implication 267
- N-terminal 269
- tetrameric structure 259-264
369
PAGE (polyacrylamide gel electrophoresis) 5,
44,84
- SOS-PAGE 184, 186, 253, 279, 322
pancreatic trypsin inhibitor 189
papain 352
peptidase, biotinylated 317
peptide
- antigenetic 336
- amino terminal groups 179
- blocking 185
- cis/trans 204
- conformation 207
- digestion (see there)
- immun precipitation 19
- isomers 204
- mapping 84
- micropurification 19,21
- molecular weight 207
- phosphatase treatment 24
- polypeptidenchain 212
- purification 24
- separation 23
- sequence 19
- thermolytic 196
- trypsin 19,50,61,81, 185
- UV-spectra 51
peptidoglycand 341
phospholipids 251
phosphopeptide
- analysis 9-12
- identification 24
photo cycle 225, 226
- photocycle intermediates, structural investigations 230-235
photolabelling 214
photoproducts 229
PITC 313
placental cells 330
platelets 330
parodontosis 289, 290
polymerase 253
polypeptide 229, 292
polysaccharide 341
- structure/function 289-292
- TIMPs, biomolecular interaction 292-298
metastasis 290
methylation 177
MHC 336
microcrystals 235-237
micro globulin 336
microsequence analysis 84
mirystoyl-group 313
monosaccharide 324, 341, 342, 346, 360, 361
morphiceptin 201
mouse 241
M -state, trapping 230-234
mucins 341
mucoproteins 341
mucorpepsin 185
multiple sclerosis 289
mutant, tumorgenetic p53 257
N
neutron diffraction 229
Newcastle disease virus (NOV) 124-127
NMR 91,201,248,321
- bimolecular 91
- chemical shift/exchange 95-97, 112
- criteria 93
- dipolar coupling
- - constants 102
- - residual 103, 104
- experimental conditions 92
- high-resolution 92
- hydrogen exchange rate constants 101, 102
- isotopic labelling 94
isotropic rotational diffusion 102, 103
nuclear Overhauser-effect 99
- protein, buffers 92
- relaxation 98
- - cross-correlated relaxation rate constant
101
- - heteronuclear relaxation rate constant 99,
100
- sample preparation 93
- scalar coupling constants 97, 98
structure determination 105-107
- spectral parameters 94, 95
- spectrometer 101, 200
- size of protein 93
- TROSY 101
- two-dimensional 91
N-terminal group 185,264
- blocking 177
- desalting 177
nuclear antigen 120
nucleic acid 143, 341, 352
- reverse stammg 30
nucleoprotein 264, 267
nucleoptide, probes 24
o
oligonucleotide probe 66
oligopeptide 202
oligosaccharide 321,325,331,341,343
- analysis of structure 133-135, 248, 249,
322-324
O-linked 151
- sequencing 322
- I)-oligosaccharide 361
- glycosic linkage 347
oncogene 257
osteoarthrosis 350
osteoarthritis 289, 290, 322
Overhauser-effect, nuclear 99
oxopeptide 208
P
p53 complex, structural model 257-270
- co-crystal-structure 260, 261
DNA twisting/bending 264-267
- function, implication 267
- N-terminal 269
- tetrameric structure 259-264
369
PAGE (polyacrylamide gel electrophoresis) 5,
44,84
- SOS-PAGE 184, 186, 253, 279, 322
pancreatic trypsin inhibitor 189
papain 352
peptidase, biotinylated 317
peptide
- antigenetic 336
- amino terminal groups 179
- blocking 185
- cis/trans 204
- conformation 207
- digestion (see there)
- immun precipitation 19
- isomers 204
- mapping 84
- micropurification 19,21
- molecular weight 207
- phosphatase treatment 24
- polypeptidenchain 212
- purification 24
- separation 23
- sequence 19
- thermolytic 196
- trypsin 19,50,61,81, 185
- UV-spectra 51
peptidoglycand 341
phospholipids 251
phosphopeptide
- analysis 9-12
- identification 24
photo cycle 225, 226
- photocycle intermediates, structural investigations 230-235
photolabelling 214
photoproducts 229
PITC 313
placental cells 330
platelets 330
parodontosis 289, 290
polymerase 253
polypeptide 229, 292
polysaccharide 341