Oxygen, 139
Oxygenase, 133, 173, 196
Oxygenation, 173
Oxytocin, 353
P
Pancreatin, 87
Pantolactone, 103
D-Pantoyl lactone, 156
Papain, 59, 70, 382
Papaya, 25
Paraoxon, 190
Parathion, 104
Parkinson’s disease, 183
Partition coefficient, 318
Pd I catalysis, 98
nanoparticles, 346
Penicillin, 9
acylase, 55, 59, 70
Penicillin G, 71, 354
Pepsin, 59
Peptide
ligases, 349
synthesis, 347–349
Peracid synthesis, 353–354
Permanganate, 176
Peroxidases, 174, 199
Peroxidation, 198–204
Peroxide-shunt, 176
Peroxyflavin, 177
Peroxygenases, 174, 199
Peroxy-stat, 204
Pesticides, 104
pH, 7
memory, 319
optimum, 75
Phase distributions, 318
Phenol, 167
Phenylacetone monooxygenase (PAMO), 188
Phenyl acetyl carbinol (PAC), 219, 363
Phenyl alanine, 228
ammonia lyase, 227–228
dehydrogenase, 161
Phenylglycine, 50
Phenyl-thioacetate, 97
Phosphatase, 104, 112–115, 213
mutants, 113
Phosphate
donor, 107
esters, 104
Phosphite dehydrogenase, 138, 192
Phosphoenol pyruvate, 107, 238, 360
Phosphoglucomutase, 237
Phosphogluconate, 138
Phospholipases, 88
Phosphonic acid, 184
Phosphopantetheinyl transferase, 368
Phosphorylase, 238
Phosphorylation, 104, 106–107, 213
Phosphotransferase, 109
Phosphotriesterase, 104
Pichia pastoris, 68
Picolinamide, 128
Pig liver esterase (PLE), 58, 61, 73
model, 83
Pineapple, 25
π–π Stacking, 12
Planar chirality, 17
Platelet-activating-factor (PAF), 98
Platform chemicals, 412
PLE isoenzymes, 65
P450 monooxygenases, 361
Polyalcohols, 322
Polyethylene glycol, 322, 380
Polyol dehydrogenase, 212
Polyphenol oxidase, 182, 316, 355
Polyphosphate, 108
kinase, 108
Polyvinyl acetate, 371
Porcine pancreatic lipase (PPL), 87–92, 332
Porous glass, 371
Posaconazol, 333
Potato, 25
Pre-catalysts, 340
Prednisolone, 104
Pregabalin, 100
Prelog’s rule, 140, 220
Prenalterol, 182
Primary
metabolism, 25
structure, 11
Prins-rearrangement, 4
Processive enzyme, 367
Productivity number (PN), 23
Progesterone, 179
Prokaryotic cells, 116
Proline residue, 234
Promiscuity, 4
Prostaglandin, 89
Protease, 58–83
Protective group, 73
Protein Data Bank (PDB), 80
design, 77
Index
431
Oxygenase, 133, 173, 196
Oxygenation, 173
Oxytocin, 353
P
Pancreatin, 87
Pantolactone, 103
D-Pantoyl lactone, 156
Papain, 59, 70, 382
Papaya, 25
Paraoxon, 190
Parathion, 104
Parkinson’s disease, 183
Partition coefficient, 318
Pd I catalysis, 98
nanoparticles, 346
Penicillin, 9
acylase, 55, 59, 70
Penicillin G, 71, 354
Pepsin, 59
Peptide
ligases, 349
synthesis, 347–349
Peracid synthesis, 353–354
Permanganate, 176
Peroxidases, 174, 199
Peroxidation, 198–204
Peroxide-shunt, 176
Peroxyflavin, 177
Peroxygenases, 174, 199
Peroxy-stat, 204
Pesticides, 104
pH, 7
memory, 319
optimum, 75
Phase distributions, 318
Phenol, 167
Phenylacetone monooxygenase (PAMO), 188
Phenyl acetyl carbinol (PAC), 219, 363
Phenyl alanine, 228
ammonia lyase, 227–228
dehydrogenase, 161
Phenylglycine, 50
Phenyl-thioacetate, 97
Phosphatase, 104, 112–115, 213
mutants, 113
Phosphate
donor, 107
esters, 104
Phosphite dehydrogenase, 138, 192
Phosphoenol pyruvate, 107, 238, 360
Phosphoglucomutase, 237
Phosphogluconate, 138
Phospholipases, 88
Phosphonic acid, 184
Phosphopantetheinyl transferase, 368
Phosphorylase, 238
Phosphorylation, 104, 106–107, 213
Phosphotransferase, 109
Phosphotriesterase, 104
Pichia pastoris, 68
Picolinamide, 128
Pig liver esterase (PLE), 58, 61, 73
model, 83
Pineapple, 25
π–π Stacking, 12
Planar chirality, 17
Platelet-activating-factor (PAF), 98
Platform chemicals, 412
PLE isoenzymes, 65
P450 monooxygenases, 361
Polyalcohols, 322
Polyethylene glycol, 322, 380
Polyol dehydrogenase, 212
Polyphenol oxidase, 182, 316, 355
Polyphosphate, 108
kinase, 108
Polyvinyl acetate, 371
Porcine pancreatic lipase (PPL), 87–92, 332
Porous glass, 371
Posaconazol, 333
Potato, 25
Pre-catalysts, 340
Prednisolone, 104
Pregabalin, 100
Prelog’s rule, 140, 220
Prenalterol, 182
Primary
metabolism, 25
structure, 11
Prins-rearrangement, 4
Processive enzyme, 367
Productivity number (PN), 23
Progesterone, 179
Prokaryotic cells, 116
Proline residue, 234
Promiscuity, 4
Prostaglandin, 89
Protease, 58–83
Protective group, 73
Protein Data Bank (PDB), 80
design, 77
Index
431