Inversion, 117, 123, 240, 257
Invertase, 360
Ionic binding, 370–371
liquids, 323–324
strength, 416
Iron binding, 157
Irreversible Reaction, 40–42
Iso-indol, 248
Isolated enzymes, 8, 10
Isomerase, 360
J
Jacobsen-catalysts, 183
epoxidation, 115
Juvenile hormone, 122
K
Katal, 22
Katsuki-Sharpless method, 183
Kazlauskas rule, 81, 85, 95, 340, 346
Kemp elimination, 389
α-Keto-adipate, 139
α-Ketoamides, 152
α-Ketocarboxylic acid, 159
α-Ketoesters, 152
β-Ketoesters, 148, 150
α-Ketoglutarate, 139, 251
decarboxylases, 222
Ketoisophorone, 165
Ketoprofen, 132
Ketorolac, 72
D-Ketose, 211
Kidney, 25
Kinase, 106–107, 213, 236
Kinetic approach, 350–353
control, 113, 242
resolution of alcohols, 333–336
Kolbe-Schmitt carboxylation, 4
Krebs-cycle, 222
Kyotorphin, 351
L
Lactam, 181
Lactamase Method, 56–58
β-Lactams, 51
Lactate, 364
dehydrogenase, 139, 247, 365, 377
Lactol, 216
Lactonase, 103
Lactones, 103–104
synthesis, 343–344
Lactonization, 343
Lamivudine, 338
Leaving group, 236, 240, 337
Leloir pathway, 236
Leuckart-Wallach reaction, 248
Leukotrienes, 90
Levodione, 165
Lewis acid, 379
Lid, 84
Light, 126
Lignin, 413
Limonene-1,2-epoxide hydrolase, 117
hydratase, 225
Lindane, 257
Lipase, 83–103, 353
Lipid-coating, 381
Lipolase™, 101
Lipoxygenase, 194
Liquid crystals, 324
formulation, 415
Liver, 25
L-Leucine-dehydrogenase, 159
Lock-and-key mechanism, 13–14
Log P, 320, 357
Lutidine, 330
Lyases, 224
Lyophilizates, 415, 417
Lysine, 248, 380
residues, 329
M
Macrolides, 343
Magic mushrooms, 104
Magnetite field, 381
Magnetite particles, 381
L-Malate, 79
Malease, 226
Maleimide, 163
Malonic diesters, 62
Maltose, 238
Manganese, 199
Mannich reaction, 157
Mediators, 139
Medium engineering, 74–75, 102, 356–357
Membrane, 315, 369, 375
enzymatic catalysis, 377
reactor, 107
Meso-dicarboxylic esters, 63
substrate, 34
trick, 35
Metabolic engineering, 359
Index
429
Invertase, 360
Ionic binding, 370–371
liquids, 323–324
strength, 416
Iron binding, 157
Irreversible Reaction, 40–42
Iso-indol, 248
Isolated enzymes, 8, 10
Isomerase, 360
J
Jacobsen-catalysts, 183
epoxidation, 115
Juvenile hormone, 122
K
Katal, 22
Katsuki-Sharpless method, 183
Kazlauskas rule, 81, 85, 95, 340, 346
Kemp elimination, 389
α-Keto-adipate, 139
α-Ketoamides, 152
α-Ketocarboxylic acid, 159
α-Ketoesters, 152
β-Ketoesters, 148, 150
α-Ketoglutarate, 139, 251
decarboxylases, 222
Ketoisophorone, 165
Ketoprofen, 132
Ketorolac, 72
D-Ketose, 211
Kidney, 25
Kinase, 106–107, 213, 236
Kinetic approach, 350–353
control, 113, 242
resolution of alcohols, 333–336
Kolbe-Schmitt carboxylation, 4
Krebs-cycle, 222
Kyotorphin, 351
L
Lactam, 181
Lactamase Method, 56–58
β-Lactams, 51
Lactate, 364
dehydrogenase, 139, 247, 365, 377
Lactol, 216
Lactonase, 103
Lactones, 103–104
synthesis, 343–344
Lactonization, 343
Lamivudine, 338
Leaving group, 236, 240, 337
Leloir pathway, 236
Leuckart-Wallach reaction, 248
Leukotrienes, 90
Levodione, 165
Lewis acid, 379
Lid, 84
Light, 126
Lignin, 413
Limonene-1,2-epoxide hydrolase, 117
hydratase, 225
Lindane, 257
Lipase, 83–103, 353
Lipid-coating, 381
Lipolase™, 101
Lipoxygenase, 194
Liquid crystals, 324
formulation, 415
Liver, 25
L-Leucine-dehydrogenase, 159
Lock-and-key mechanism, 13–14
Log P, 320, 357
Lutidine, 330
Lyases, 224
Lyophilizates, 415, 417
Lysine, 248, 380
residues, 329
M
Macrolides, 343
Magic mushrooms, 104
Magnetite field, 381
Magnetite particles, 381
L-Malate, 79
Malease, 226
Maleimide, 163
Malonic diesters, 62
Maltose, 238
Manganese, 199
Mannich reaction, 157
Mediators, 139
Medium engineering, 74–75, 102, 356–357
Membrane, 315, 369, 375
enzymatic catalysis, 377
reactor, 107
Meso-dicarboxylic esters, 63
substrate, 34
trick, 35
Metabolic engineering, 359
Index
429
