Glycohydrolases, 240
Glycol-monoester intermediate, 116
Glycols, 169
Glycosidases, 117, 236
Glycosidic linkage, 237
Glycosyl donors, 242
enzyme intermediate, 117
phosphorylases, 236
transfer, 235–245
transferases, 235–236
Glyco-Synthases, 245
Gore-Tex, 378
Ground state, 18
H
α-Haloacid Dehalogenases, 258–259
Haloalkane dehalogenases, 116, 257–258
Halogenation, 201, 250–261
Halohydrin, 253, 334
dehalogenase, 124, 259–261
Haloketones, 255
Halolactonization, 253
Halonium intermediate, 252
Haloperoxidases, 251
Health hazards, 415
Helminthosporium sp., 188
Heme, 8, 199
Hemi(thio)acetals, 337
Hemiaminals, 337
Henry-reaction, 229–233
Hepatic epoxide hydrolases, 118–119
Hevea brasiliensis, 230
Hexokinase, 109, 360
Hexoses, 171
High-pressure, 324
Hildebrandt solubility parameter, 320
H 2 O 2 , 139, 251
Hog kidney, 55
Horse liver ADH, 141, 169
esterases, 58
Horseradish, 252
peroxidase, 199, 382
Hydantoinase Method, 55–56
Hydantoin racemases, 56
Hydratases, 225
Hydration, 224
Hydrazides, 344
Hydrazinolysis, 33, 344
Hydroamination, 227
Hydrogen, 358
bonds, 12, 77
borrowing, 193
cyanide, 229
peroxide, 33, 198, 200
Hydrogenase, 138
Hydrolysis of nitriles, 124–133
Hydroperoxidation, 194–196
Hydroperoxide, 193, 336
Hydroxamic acid, 33
Hydroxyacetaldehyde, 207
Hydroxyacetone monooxygenase (HAPMO),
188
ω-Hydroxylase, 184
Hydroxylation, 133, 201–202
of alkanes, 178–181
of aromatic compound, 182–183
5-Hydroxymethyl furfural oxidase (HMF
oxidase), 171
Hydroxymuconate, 234
6-Hydroxynicotinic acid, 182
Hydroxynitrile lyase (HNLs), 229
Hydroxynitriles, 362
Hydroxypyruvate, 223
Hyperthermophilic, 240
Hypohalite, 251
Hypohalous acid, 252
I
Ibuprofen, 69, 132
Imine reductases, 157
Iminium, 159
Immobilization, 147, 317, 369–379
of cofactors, 378–379
Immobilized enzymes, 417
Immune system, 386
Indane-1,2-diol, 156
Indinavir, 156, 198
Induced fit, 317
mechanism, 12, 14
Inducer, 127, 418
Industrial scale, 154, 179, 182, 184, 197, 214,
216, 246, 249
processes, 407
Inhibition, 8, 103, 147, 149, 153
Inhibitors, 190, 416
Inosine 5’-phosphate, 114
Insecticide, 232
In-situ inversion, 47
racemization, 72, 338
Insulin, 352
Interfacial activation, 83
International Union of Biochemistry and
Molecular Biology (IUBMB), 20
International Unit, 22
428
Index
Glycol-monoester intermediate, 116
Glycols, 169
Glycosidases, 117, 236
Glycosidic linkage, 237
Glycosyl donors, 242
enzyme intermediate, 117
phosphorylases, 236
transfer, 235–245
transferases, 235–236
Glyco-Synthases, 245
Gore-Tex, 378
Ground state, 18
H
α-Haloacid Dehalogenases, 258–259
Haloalkane dehalogenases, 116, 257–258
Halogenation, 201, 250–261
Halohydrin, 253, 334
dehalogenase, 124, 259–261
Haloketones, 255
Halolactonization, 253
Halonium intermediate, 252
Haloperoxidases, 251
Health hazards, 415
Helminthosporium sp., 188
Heme, 8, 199
Hemi(thio)acetals, 337
Hemiaminals, 337
Henry-reaction, 229–233
Hepatic epoxide hydrolases, 118–119
Hevea brasiliensis, 230
Hexokinase, 109, 360
Hexoses, 171
High-pressure, 324
Hildebrandt solubility parameter, 320
H 2 O 2 , 139, 251
Hog kidney, 55
Horse liver ADH, 141, 169
esterases, 58
Horseradish, 252
peroxidase, 199, 382
Hydantoinase Method, 55–56
Hydantoin racemases, 56
Hydratases, 225
Hydration, 224
Hydrazides, 344
Hydrazinolysis, 33, 344
Hydroamination, 227
Hydrogen, 358
bonds, 12, 77
borrowing, 193
cyanide, 229
peroxide, 33, 198, 200
Hydrogenase, 138
Hydrolysis of nitriles, 124–133
Hydroperoxidation, 194–196
Hydroperoxide, 193, 336
Hydroxamic acid, 33
Hydroxyacetaldehyde, 207
Hydroxyacetone monooxygenase (HAPMO),
188
ω-Hydroxylase, 184
Hydroxylation, 133, 201–202
of alkanes, 178–181
of aromatic compound, 182–183
5-Hydroxymethyl furfural oxidase (HMF
oxidase), 171
Hydroxymuconate, 234
6-Hydroxynicotinic acid, 182
Hydroxynitrile lyase (HNLs), 229
Hydroxynitriles, 362
Hydroxypyruvate, 223
Hyperthermophilic, 240
Hypohalite, 251
Hypohalous acid, 252
I
Ibuprofen, 69, 132
Imine reductases, 157
Iminium, 159
Immobilization, 147, 317, 369–379
of cofactors, 378–379
Immobilized enzymes, 417
Immune system, 386
Indane-1,2-diol, 156
Indinavir, 156, 198
Induced fit, 317
mechanism, 12, 14
Inducer, 127, 418
Industrial scale, 154, 179, 182, 184, 197, 214,
216, 246, 249
processes, 407
Inhibition, 8, 103, 147, 149, 153
Inhibitors, 190, 416
Inosine 5’-phosphate, 114
Insecticide, 232
In-situ inversion, 47
racemization, 72, 338
Insulin, 352
Interfacial activation, 83
International Union of Biochemistry and
Molecular Biology (IUBMB), 20
International Unit, 22
428
Index