7 In Situ Hybridization for RNA: Radioactive DNA Probe
113
Fig. 3. mRNA of matrix metalloproteinase-1 (MMP-l), stimulated by 1L-1 (left)
and by y-1FN (right).
Synovial Cell
Endothelial Cell
Fibroblast
Vascular Myocyte
Lymphocyte
Neutrophil
Red Blood Cdl
Synovial Ce ll
Endothelial Cell
Fibroblast
Vascular Myocyte
Lymphocyte
Neutrophil
Red Blood Cell
Rheumatoid Arthritis
5
10
Grains/ Cell
Osteoarthritis
5
10
Fig. 4. Numbers of silver grains ofMMP-3 among cells comprising rheumatoid
and osteoarthritic synovia.