70
P.-E. E. BERGNER
References
1. BERGNER, P.-E. E.: J. Theor. BioI. 1, 120 (1961).
2.
USAEC Report, ORAU-103 (1967).
3.
J. Thear. BioI. 6, 137 (1964).
4.
USAEC Report, ORAU-104 (1967).
Discussion
SMITH:
I would like an explanation of the compartments mI , m21 and m 22 in relation
to (a) physiological compartments and (b) output compartments.
BERGNER:
mi is the steady state amount of particles (e. g. in grams) which stay in the
system no longer than 11' m21 is the corresponding number of particles that
have stayed in the system less than 11, but are known to leave before 12 but not
before 11 (note, 11 < 12), m22 is the steady state amount of particles which have
stayed in the system longer than 11 but are known to leave before '2'-The
identification of all the turnover compartments with different physiological
compartments is not given by the present theory, but must be done separately.
That is, such an identification is by necessity hypothetical and must be tested
by separate experiments. The specific identification I made of the "final" compartments in the cow diagrams is in agreement with separate observations of
calcium content in blood and feces.-The identification I made of the change in
relative turnover cannot, so far as I know, be verified by any other method.
However, as this identification is rather obvious, it suggests that we here have
a method for studying the change of the bone calcium turnover.
P.-E. E. BERGNER
References
1. BERGNER, P.-E. E.: J. Theor. BioI. 1, 120 (1961).
2.
USAEC Report, ORAU-103 (1967).
3.
J. Thear. BioI. 6, 137 (1964).
4.
USAEC Report, ORAU-104 (1967).
Discussion
SMITH:
I would like an explanation of the compartments mI , m21 and m 22 in relation
to (a) physiological compartments and (b) output compartments.
BERGNER:
mi is the steady state amount of particles (e. g. in grams) which stay in the
system no longer than 11' m21 is the corresponding number of particles that
have stayed in the system less than 11, but are known to leave before 12 but not
before 11 (note, 11 < 12), m22 is the steady state amount of particles which have
stayed in the system longer than 11 but are known to leave before '2'-The
identification of all the turnover compartments with different physiological
compartments is not given by the present theory, but must be done separately.
That is, such an identification is by necessity hypothetical and must be tested
by separate experiments. The specific identification I made of the "final" compartments in the cow diagrams is in agreement with separate observations of
calcium content in blood and feces.-The identification I made of the change in
relative turnover cannot, so far as I know, be verified by any other method.
However, as this identification is rather obvious, it suggests that we here have
a method for studying the change of the bone calcium turnover.