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F. Glorius, K. Hirano
Scheme 2. Modes of action of NHCs in organocatalysis
Scheme 3. Different types of NHC
(Scheme 3). Subtle structural differences can have a pronounced
effect on catalytic activity and selectivity.
3. Based on the R substituents in the 1- and 3-positions of the NHC,
the area around the carbene carbon can be greatly influenced, allowing the design and adjustment for a variety of different applications (Fig. 2).
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