Reactions at Oxygen Atoms
2.1
139
⊡ Scheme 41
Use of benzyloxycarbonyl group in the synthesis of a 1-O-carboxyalkyl GLA-60 analogue
⊡ Scheme 42
Palladium (0)-mediated cleavage of allyloxycarbonyl groups
An impressive example of how this protecting group has become a powerful tool for the
construction of glycopeptides and oligosaccharides comes from the first synthesis of the glycopeptide nephritogenoside [272]. Its structure shows a trisaccharide composed of three glucose moieties linked to a peptide of 21 aminoacids. Taking into account the instability of the
2.1
139
⊡ Scheme 41
Use of benzyloxycarbonyl group in the synthesis of a 1-O-carboxyalkyl GLA-60 analogue
⊡ Scheme 42
Palladium (0)-mediated cleavage of allyloxycarbonyl groups
An impressive example of how this protecting group has become a powerful tool for the
construction of glycopeptides and oligosaccharides comes from the first synthesis of the glycopeptide nephritogenoside [272]. Its structure shows a trisaccharide composed of three glucose moieties linked to a peptide of 21 aminoacids. Taking into account the instability of the