Plasma volume
Na
Na
Plasma volume
Renal sympathetic nerve
Arterial pressure sensing
Blood pressure sensing
Renin secretion
Extracellular fluid
osmolality
Cardiopulmonary
baroreceptor
Pituitary
Water conserved
Kidneycollecting duct
Decrease Na retention
(Natriuresis)
Kidney
Kidney
Blood vessel
Pulmonary
renal endothelium
Adrenal cortex
Kidney
Collecting duct
Na reabsorption
Aldosterone secretion
ACE action
ANGI ANGII
AQP2 trafficking to PM
water reabsorption
ANGI
AGT
Inhibit
AVP secretion
JGA
Heart
Na excretion
ANP secretion
Na conserved
Water
Water
Interacting
Interacting
Figure 7.3 General schematics of the functions of osmoregulatory hormones. (ACE, angiotensin
I-converting enzyme; AGT, angiotensinogen; ANG, angiotensin; ANP, atrial natriuretic peptide;
AVP, arginine vasopressin; juxta-glomerular apparatus cells in the kidney; PM, plasma membrane.)