78
L. Acosta-Soto and S. Hosseini
Table 3.1
(continued)
BioMEMS platform
Main components
Fabrication strategy
Mechanisms of
operation
Detected analyte
Specifics
Ref
• PDMS chip
• Bacterial trap
Poly-Si-photogate
Through soft
lithography, the
PDMS chip was made
from SU-8 mold and
subjected to oxygen
plasma to bind to lid.
Channel and chamber
geometry were
defined accordingly to
accommodate the
micro-beads. Si-photo
sensor was placed
directly below the
chip
Bacteria solution was
pumped into the chip
along with
microbeads that
helped trapping them
within the setup
fluorescence
detection. The sample
was excited through a
UV light source,
which was turned off
to allow the
Si-photogate to detect
the fluorescent signals
L. pneumophila cells This method
offered a highly
sensitive and timely
option to identify
bacterial presence
without the need
for optical sensors
of more complex
equipment for
detection
Onishi (2017)
Electro-mechanical
sensor
• 3D printed case
• Microcontroller
• Circuitry
• Sample loading
port
A ready-to-use
biosensor that
integrates a
microcontroller, and
corresponding
circuitry to control a
LED for excitation
Prior to loading the
analyte solution, the
device was calibrated
with known
concentrations for
efficiently estimating
the biomass
composition of
unknown sample
• Chlorophyll A and
B
• Phycocyanin
The error rate of the
device was rather
high (2–16%)
Shin et al.
(2018)
(continued)