3 Bio-microelectromechanical Systems (BioMEMS) in Bio-sensing …
79
Table 3.1
(continued)
BioMEMS platform
Main components
Fabrication strategy
Mechanisms of
operation
Detected analyte
Specifics
Ref
Alternative
BioMEMS
• Micro-bead
• RhB
• FITC
Micro-beads were
first incubated in
alcohol solution to
cause swelling. RhB
penetrated the
network and stained
the beads. The beads
were washed in
deionized water to
close the pores.
Finally, it was
submerged in a
saturated solution
containing FITC for
staining and imaging
Upon excitation, the
two fluorophores
emitted different
responses, one
dependent solely on
temperature (rhB),
and another both on
temperature and pH
(FITC). This
difference was used to
identify them
Amino-PS beads
based on temperature
and pH
Sensor offered a
great accuracy at
0.1 °C and 0.2 pH
Liu et al.
(2014)
(continued)
79
Table 3.1
(continued)
BioMEMS platform
Main components
Fabrication strategy
Mechanisms of
operation
Detected analyte
Specifics
Ref
Alternative
BioMEMS
• Micro-bead
• RhB
• FITC
Micro-beads were
first incubated in
alcohol solution to
cause swelling. RhB
penetrated the
network and stained
the beads. The beads
were washed in
deionized water to
close the pores.
Finally, it was
submerged in a
saturated solution
containing FITC for
staining and imaging
Upon excitation, the
two fluorophores
emitted different
responses, one
dependent solely on
temperature (rhB),
and another both on
temperature and pH
(FITC). This
difference was used to
identify them
Amino-PS beads
based on temperature
and pH
Sensor offered a
great accuracy at
0.1 °C and 0.2 pH
Liu et al.
(2014)
(continued)