76
L. Acosta-Soto and S. Hosseini
Table 3.1
(continued)
BioMEMS platform
Main components
Fabrication strategy
Mechanisms of
operation
Detected analyte
Specifics
Ref
• CELL chips
Oval-shaped
chambers
• CGG
• Inlets
• MIX chip
The chips were
fabricated by
soft-lithography and
wet etching. Each
resulting PDMS
substrate was bonded
to a glass surface by
exposing the samples
to air plasma
HeLa cells were
cultured in 5 different
CELL chips. The
CELL chips are
disconnected from the
CGG chip to be
placed within
incubator. The MIX
chip was connected to
the CELL chip to let
the probe solution
interact with the cells
PS beads as model
analyte
Proposed platform
reduces the time
necessary for the
assay by ~40%
Montón et al.
(2017)
(continued)