2 Bio-microelectromechanical Systems (BioMEMS) …
23
Table 2.1
(continued)
BioMEMS platform
Main components
Fabrication strategy Mechanisms of
operation
Detected analyte
Specifics
References
PAD ELISA platform • Wax-printed
96-microzone paper
plate
• Image interpretation
device
• AuNPs
The AuNPs were
synthesized through
citrate-reduction
techniques, later
joined with PEG and
were added to the
IgG antibodies. A
wax printing method
was used to create
the pattern on the
paper designed. The
dimensions were
according to the
standard Costar
96-well microtiter
plate
A direct ELISA
protocol was
performed in the
device to detect the
IgG with a
colorimetric substrate.
Multiple P-ELISAs
were conducted in
parallel, allowing the
use of common
microplate processing
techniques with the
P-ELISA format
Neuropeptide Y
This device
provides an
inexpensive
platform to carry
out highly sensitive
(picomolar level)
biomolecular
assays at very low
sample and reagent
volumes
Murdock
et al. (2013)
(continued)