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M. A. Espinosa-Hernandez et al.
Table 2.1
Recent BioMEMS platforms for colorimetric detection: Type of the platform, main components, fabrication strategy, mechanism of operation. The
analyte of interest, and the advantages and disadvantages of each platform are presented in this table
BioMEMS platform
Main components
Fabrication strategy Mechanisms of
operation
Detected analyte
Specifics
References
PAD DNA sensor
based on
acpcPNA-induced
nanoparticle
aggregation
• AgNP
• acpcPN probe
• PAD Multiplex DNA
• Sensor
The PAD was made
with a wax-printing
technique and the
sensor by folding
two-layer halves
while a PDMS lid
held it together
The sample reservoir
was punched through
the whole device. The
acpcPNA probe and
AgNPs solution were
added onto the
detection and control
zones. Finally, the
sample solution was
added onto the sample
reservoir and flow
through the channels
to wet the colorimetric
detection zones
• MERS
• TB
• MERS-CoV
• HPV
This colorimetric
DNA sensor
exhibited high
selectivity and has
the potential to be a
low-cost and
disposable
alternative tool for
rapid and selective
screening and
detecting in
infectious diseases
Teengam
et al. (2017)
(continued)