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A. Kumar et al.
is covered by a protective layer of proteins. This protective layer of proteins called
capsid and these capsid varies in shape like spherical, simple helical, and helical with
more complex structures having tails. Figure 4 shows the self-assembled icosahedral
structure of the herpes simplex virus (HSV-1). The tobacco virus was the first virus
to be discovered whose self-assembled helical structure is shown in Fig. 5. As shown
in Fig. 5a, the dimensions of the tobacco mosaic virus are approximately 300 nm in
length and 18 nm in diameter.
Fig. 4 Structures of the HSV-1 virion and capsid. a Electron micrograph showing a single HSV-1
virion in cross-section. b CryoEM reconstruction of an HSV-1 capsid shown in surface-shaded
representation viewed along a face (3-fold axis). c View of the HSV-1 capsid with a single hexon
and a single major capsid protein molecule extracted. Reproduced from [22]
A. Kumar et al.
is covered by a protective layer of proteins. This protective layer of proteins called
capsid and these capsid varies in shape like spherical, simple helical, and helical with
more complex structures having tails. Figure 4 shows the self-assembled icosahedral
structure of the herpes simplex virus (HSV-1). The tobacco virus was the first virus
to be discovered whose self-assembled helical structure is shown in Fig. 5. As shown
in Fig. 5a, the dimensions of the tobacco mosaic virus are approximately 300 nm in
length and 18 nm in diameter.
Fig. 4 Structures of the HSV-1 virion and capsid. a Electron micrograph showing a single HSV-1
virion in cross-section. b CryoEM reconstruction of an HSV-1 capsid shown in surface-shaded
representation viewed along a face (3-fold axis). c View of the HSV-1 capsid with a single hexon
and a single major capsid protein molecule extracted. Reproduced from [22]