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JH, Cho YW, Kim BS, Kim SK, Lee T, Kim D, Lee S, Pomper MG, Kwon IC, Kim K (2017)
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217. Rosen JE, Chan L, Shieh DB, Gu FX (2012) Iron oxide nanoparticles for targeted cancer
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1016/j.nano.2011.08.017
218. Li J, Zheng L, Cai H, Sun W, Shen M, Zhang G, Shi X (2013) Polyethyleneimine-mediated
synthesis of folic acid-targeted iron oxide nanoparticles for in vivo tumor MR imaging.
Biomaterials 34(33):8382–8392. https://doi.org/10.1016/j.biomaterials.2013.07.070
219. Nyberg S, Abbott NJ, Shi X, Steyger PS, Dabdoub A (2019) Delivery of therapeutics to the
inner ear: the challenge of the blood-labyrinth barrier. Sci Transl Med 11(482). https://doi.
org/10.1126/scitranslmed.aao0935
220. Sweeney MD, Sagare AP, Zlokovic BV (2018) Blood-brain barrier breakdown in Alzheimer
disease and other neurodegenerative disorders. Nat Rev Neurol 14(3):133–150. https://doi.
org/10.1038/nrneurol.2017.188
N. Ashwin Kumar et al.
206. Yu MK, Jeong YY, Park J, Park S, Kim JW, Min JJ, Kim K, Jon S (2008) Drug-loaded
superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo.
Angew Chem 47(29):5362–5365. https://doi.org/10.1002/anie.200800857
207. Saraswathy A, Nazeer SS, Jeevan M, Nimi N, Arumugam S, Harikrishnan VS, Varma PR,
Jayasree RS (2014) Citrate coated iron oxide nanoparticles with enhanced relaxivity for in vivo
magnetic resonance imaging of liver fibrosis. Coll Surf B Biointerfaces 117:216–224. https://
doi.org/10.1016/j.colsurfb.2014.02.034
208. Liu D, Wu W, Ling J, Wen S, Gu N, Zhang X (2011) Effective PEGylation of iron oxide
nanoparticles for high performance in vivo cancer imaging. Adv Func Mater 21(8):1498–1504.
https://doi.org/10.1002/adfm.201001658
209. Ye F, Laurent S, Fornara A, Astolfi L, Qin J, Roch A, Martini A, Toprak MS, Muller RN,
Muhammed M (2012) Uniform mesoporous silica coated iron oxide nanoparticles as a highly
efficient, nontoxic MRI T(2) contrast agent with tunable proton relaxivities. Contrast Media
Mol Imaging 7(5):460–468. https://doi.org/10.1002/cmmi.1473
210. Mahmoudi M, Hosseinkhani H, Hosseinkhani M, Boutry S, Simchi A, Journeay WS, Subramani K, Laurent S (2011) Magnetic resonance imaging tracking of stem cells in vivo using
iron oxide nanoparticles as a tool for the advancement of clinical regenerative medicine. Chem
Rev 111(2):253–280. https://doi.org/10.1021/cr1001832
211. Andreas K, Georgieva R, Ladwig M, Mueller S, Notter M, Sittinger M, Ringe J (2012)
Highly efficient magnetic stem cell labeling with citrate-coated superparamagnetic iron oxide
nanoparticles for MRI tracking. Biomaterials 33(18):4515–4525. https://doi.org/10.1016/j.
biomaterials.2012.02.064
212. Azevedo-Pereira RL, Rangel B, Tovar-Moll F, Gasparetto EL, Attias M, Zaverucha-do-Valle
C, Jasmin Mendez-Otero R (2019) Superparamagnetic iron oxide nanoparticles as a tool to
track mouse neural stem cells in vivo. Mol Biol Rep 46(1):191–198. https://doi.org/10.1007/
s11033-018-4460-9
213. Zare S, Mehrabani D, Jalli R, Saeedi Moghadam M, Manafi N, Mehrabani G, Jamhiri I,
Ahadian S (2019) MRI-tracking of dental pulp stem cells in vitro and in vivo using dextrancoated superparamagnetic iron oxide nanoparticles. J Clin Med 8(9). https://doi.org/10.3390/
jcm8091418
214. Parkins KM, Makela AV, Hamilton AM, Foster PJ (2019) Cellular magnetic resonance
imaging for tracking metastatic cancer cells in the brain. Methods Mol Biol 1869:239–251.
https://doi.org/10.1007/978-1-4939-8805-1_20
215. Ashraf S, Taylor A, Sharkey J, Barrow M, Murray P, Wilm B, Poptani H, Rosseinsky MJ,
Adams DJ, Lévy R (2019) In vivo fate of free and encapsulated iron oxide nanoparticles after
injection of labelled stem cells. Nanoscale Adv 1(1):367–377. https://doi.org/10.1039/c8na00
098k
216. Lee S, Yoon HI, Na JH, Jeon S, Lim S, Koo H, Han SS, Kang SW, Park SJ, Moon SH, Park
JH, Cho YW, Kim BS, Kim SK, Lee T, Kim D, Lee S, Pomper MG, Kwon IC, Kim K (2017)
In vivo stem cell tracking with imageable nanoparticles that bind bioorthogonal chemical
receptors on the stem cell surface. Biomaterials 139:12–29. https://doi.org/10.1016/j.biomat
erials.2017.05.050
217. Rosen JE, Chan L, Shieh DB, Gu FX (2012) Iron oxide nanoparticles for targeted cancer
imaging and diagnostics. Nanomed Nanotechnol Biol Med 8(3):275–290. https://doi.org/10.
1016/j.nano.2011.08.017
218. Li J, Zheng L, Cai H, Sun W, Shen M, Zhang G, Shi X (2013) Polyethyleneimine-mediated
synthesis of folic acid-targeted iron oxide nanoparticles for in vivo tumor MR imaging.
Biomaterials 34(33):8382–8392. https://doi.org/10.1016/j.biomaterials.2013.07.070
219. Nyberg S, Abbott NJ, Shi X, Steyger PS, Dabdoub A (2019) Delivery of therapeutics to the
inner ear: the challenge of the blood-labyrinth barrier. Sci Transl Med 11(482). https://doi.
org/10.1126/scitranslmed.aao0935
220. Sweeney MD, Sagare AP, Zlokovic BV (2018) Blood-brain barrier breakdown in Alzheimer
disease and other neurodegenerative disorders. Nat Rev Neurol 14(3):133–150. https://doi.
org/10.1038/nrneurol.2017.188