Nanomaterials for Medical Imaging …
393
158. Salehi B, Selamoglu Z, K SM, Pezzani R, Redaelli M, Cho WC, Kobarfard F, Rajabi S,
Martorell M, Kumar P, Martins N, Subhra Santra T, Sharifi-Rad J (2019) Liposomal cytarabine
as cancer therapy: from chemistry to medicine. Biomolecules 9(12). https://doi.org/10.3390/
biom9120773
159. Langereis S, Geelen T, Grull H, Strijkers GJ, Nicolay K (2013) Paramagnetic liposomes for
molecular MRI and MRI-guided drug delivery. NMR Biomed 26(7):728–744. https://doi.org/
10.1002/nbm.2971
160. Liu X, Madhankumar AB, Miller PA, Duck KA, Hafenstein S, Rizk E, Slagle-Webb
B, Sheehan JM, Connor JR, Yang QX (2016) MRI contrast agent for targeting glioma:
interleukin-13 labeled liposome encapsulating gadolinium-DTPA. Neuro Oncol 18(5):691–
699. https://doi.org/10.1093/neuonc/nov263
161. Li W, Su B, Meng S, Ju L, Yan L, Ding Y, Song Y, Zhou W, Li H, Tang L, Zhao Y, Zhou
C (2011) RGD-targeted paramagnetic liposomes for early detection of tumor: in vitro and
in vivo studies. Eur J Radiol 80(2):598–606. https://doi.org/10.1016/j.ejrad.2011.01.051
162. Song Y, Li W, Meng S, Zhou W, Su B, Tang L, Zhao Y, Wu X, Yin D, Fan M, Zhou C
(2018) Dual integrin alphavbeta 3 and NRP-1-targeting paramagnetic liposome for tumor
early detection in magnetic resonance imaging. Nanoscale Res Lett 13(1):380. https://doi.
org/10.1186/s11671-018-2797-6
163. Hammoud DA (2016) Molecular imaging of inflammation: current status. J Nucl Med: Off
Publ, Soc Nucl Med 57(8):1161–1165. https://doi.org/10.2967/jnumed.115.161182
164. Tian B, Liu R, Chen S, Chen L, Liu F, Jia G, Dong Y, Li J, Chen H, Lu J (2017) Mannosecoated gadolinium liposomes for improved magnetic resonance imaging in acute pancreatitis.
Int J Nanomed 12:1127–1141. https://doi.org/10.2147/IJN.S123290
165. Dawood S (2010) Triple-negative breast cancer: epidemiology and management options.
Drugs 70(17):2247–2258. https://doi.org/10.2165/11538150-000000000-00000
166. Goldman E, Zinger A, da Silva D, Yaari Z, Kajal A, Vardi-Oknin D, Goldfeder M, Schroeder
JE, Shainsky-Roitman J, Hershkovitz D, Schroeder A (2017) Nanoparticles target early-stage
breast cancer metastasis in vivo. Nanotechnology 28(43):43LT01. https://doi.org/10.1088/
1361-6528/aa8a3d
167. Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R,
Azzi J, Nicolay K, Tannous BA (2015) Multimodal targeted high relaxivity thermosensitive
liposome for in vivo imaging. Sci Rep 5:17220. https://doi.org/10.1038/srep17220
168. Lorenzato C, Oerlemans C, van Elk M, Geerts WJ, Denis de Senneville B, Moonen C, Bos
C (2016) MRI monitoring of nanocarrier accumulation and release using Gadolinium-SPIO
co-labelled thermosensitive liposomes. Contrast Media Mol Imaging 11(3):184–194. https://
doi.org/10.1002/cmmi.1679
169. Affram K, Udofot O, Singh M, Krishnan S, Reams R, Rosenberg J, Agyare E (2017) Smart
thermosensitive liposomes for effective solid tumor therapy and in vivo imaging. PLoS One
12(9):e0185116. https://doi.org/10.1371/journal.pone.0185116
170. Ahren M, Selegard L, Klasson A, Soderlind F, Abrikossova N, Skoglund C, Bengtsson T,
Engstrom M, Kall PO, Uvdal K (2010) Synthesis and characterization of PEGylated Gd2O3
nanoparticles for MRI contrast enhancement. Langmuir: ACS J Surf Colloids 26(8):5753–
5762. https://doi.org/10.1021/la903566y
171. Soderlind F, Pedersen H, Petoral RM Jr, Kall PO, Uvdal K (2005) Synthesis and characterisation of Gd2O3 nanocrystals functionalised by organic acids. J Colloid Interface Sci
288(1):140–148. https://doi.org/10.1016/j.jcis.2005.02.089
172. Faucher L, Guay-Begin AA, Lagueux J, Cote MF, Petitclerc E, Fortin MA (2011) Ultra-small
gadolinium oxide nanoparticles to image brain cancer cells in vivo with MRI. Contrast Media
Mol Imaging 6(4):209–218. https://doi.org/10.1002/cmmi.420
173. Faucher L, Gossuin Y, Hocq A, Fortin MA (2011) Impact of agglomeration on the relaxometric
properties of paramagnetic ultra-small gadolinium oxide nanoparticles. Nanotechnology
22(29):295103. https://doi.org/10.1088/0957-4484/22/29/295103
174. Park JY, Baek MJ, Choi ES, Woo S, Kim JH, Kim TJ, Jung JC, Chae KS, Chang Y, Lee GH
(2009) Paramagnetic ultrasmall gadolinium oxide nanoparticles as advanced T1 MRI contrast
393
158. Salehi B, Selamoglu Z, K SM, Pezzani R, Redaelli M, Cho WC, Kobarfard F, Rajabi S,
Martorell M, Kumar P, Martins N, Subhra Santra T, Sharifi-Rad J (2019) Liposomal cytarabine
as cancer therapy: from chemistry to medicine. Biomolecules 9(12). https://doi.org/10.3390/
biom9120773
159. Langereis S, Geelen T, Grull H, Strijkers GJ, Nicolay K (2013) Paramagnetic liposomes for
molecular MRI and MRI-guided drug delivery. NMR Biomed 26(7):728–744. https://doi.org/
10.1002/nbm.2971
160. Liu X, Madhankumar AB, Miller PA, Duck KA, Hafenstein S, Rizk E, Slagle-Webb
B, Sheehan JM, Connor JR, Yang QX (2016) MRI contrast agent for targeting glioma:
interleukin-13 labeled liposome encapsulating gadolinium-DTPA. Neuro Oncol 18(5):691–
699. https://doi.org/10.1093/neuonc/nov263
161. Li W, Su B, Meng S, Ju L, Yan L, Ding Y, Song Y, Zhou W, Li H, Tang L, Zhao Y, Zhou
C (2011) RGD-targeted paramagnetic liposomes for early detection of tumor: in vitro and
in vivo studies. Eur J Radiol 80(2):598–606. https://doi.org/10.1016/j.ejrad.2011.01.051
162. Song Y, Li W, Meng S, Zhou W, Su B, Tang L, Zhao Y, Wu X, Yin D, Fan M, Zhou C
(2018) Dual integrin alphavbeta 3 and NRP-1-targeting paramagnetic liposome for tumor
early detection in magnetic resonance imaging. Nanoscale Res Lett 13(1):380. https://doi.
org/10.1186/s11671-018-2797-6
163. Hammoud DA (2016) Molecular imaging of inflammation: current status. J Nucl Med: Off
Publ, Soc Nucl Med 57(8):1161–1165. https://doi.org/10.2967/jnumed.115.161182
164. Tian B, Liu R, Chen S, Chen L, Liu F, Jia G, Dong Y, Li J, Chen H, Lu J (2017) Mannosecoated gadolinium liposomes for improved magnetic resonance imaging in acute pancreatitis.
Int J Nanomed 12:1127–1141. https://doi.org/10.2147/IJN.S123290
165. Dawood S (2010) Triple-negative breast cancer: epidemiology and management options.
Drugs 70(17):2247–2258. https://doi.org/10.2165/11538150-000000000-00000
166. Goldman E, Zinger A, da Silva D, Yaari Z, Kajal A, Vardi-Oknin D, Goldfeder M, Schroeder
JE, Shainsky-Roitman J, Hershkovitz D, Schroeder A (2017) Nanoparticles target early-stage
breast cancer metastasis in vivo. Nanotechnology 28(43):43LT01. https://doi.org/10.1088/
1361-6528/aa8a3d
167. Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R,
Azzi J, Nicolay K, Tannous BA (2015) Multimodal targeted high relaxivity thermosensitive
liposome for in vivo imaging. Sci Rep 5:17220. https://doi.org/10.1038/srep17220
168. Lorenzato C, Oerlemans C, van Elk M, Geerts WJ, Denis de Senneville B, Moonen C, Bos
C (2016) MRI monitoring of nanocarrier accumulation and release using Gadolinium-SPIO
co-labelled thermosensitive liposomes. Contrast Media Mol Imaging 11(3):184–194. https://
doi.org/10.1002/cmmi.1679
169. Affram K, Udofot O, Singh M, Krishnan S, Reams R, Rosenberg J, Agyare E (2017) Smart
thermosensitive liposomes for effective solid tumor therapy and in vivo imaging. PLoS One
12(9):e0185116. https://doi.org/10.1371/journal.pone.0185116
170. Ahren M, Selegard L, Klasson A, Soderlind F, Abrikossova N, Skoglund C, Bengtsson T,
Engstrom M, Kall PO, Uvdal K (2010) Synthesis and characterization of PEGylated Gd2O3
nanoparticles for MRI contrast enhancement. Langmuir: ACS J Surf Colloids 26(8):5753–
5762. https://doi.org/10.1021/la903566y
171. Soderlind F, Pedersen H, Petoral RM Jr, Kall PO, Uvdal K (2005) Synthesis and characterisation of Gd2O3 nanocrystals functionalised by organic acids. J Colloid Interface Sci
288(1):140–148. https://doi.org/10.1016/j.jcis.2005.02.089
172. Faucher L, Guay-Begin AA, Lagueux J, Cote MF, Petitclerc E, Fortin MA (2011) Ultra-small
gadolinium oxide nanoparticles to image brain cancer cells in vivo with MRI. Contrast Media
Mol Imaging 6(4):209–218. https://doi.org/10.1002/cmmi.420
173. Faucher L, Gossuin Y, Hocq A, Fortin MA (2011) Impact of agglomeration on the relaxometric
properties of paramagnetic ultra-small gadolinium oxide nanoparticles. Nanotechnology
22(29):295103. https://doi.org/10.1088/0957-4484/22/29/295103
174. Park JY, Baek MJ, Choi ES, Woo S, Kim JH, Kim TJ, Jung JC, Chae KS, Chang Y, Lee GH
(2009) Paramagnetic ultrasmall gadolinium oxide nanoparticles as advanced T1 MRI contrast