290
A. V. Ravi et al.
Table 1
List of QS systems, signal molecules and identified QSI compounds for aquaculture pathogens (Zhao et al. 2015)
Pathogens
Signal molecules
QS regulated phenotypic
factors
Host organism
Diseases
Reported QSI
compounds
V. harveyi
3-hydroxy-C4-HSL,
AI-2 and CAI-1
Bioluminescence,
Biofilm formation,
Extracellular toxins and
metalloprotease
Shrimp, Abalone, Oyster
and Fish
Luminescent vibriosis,
Skin ulcer, Septicemia
and Gastroenteritis
resulting in mass
mortality
Halogenated furanones,
Cinnamaldehyde,
Brominated
thiophenone, Curcumin,
Boric acid and
Flavonoids and citrus
limonoids
V. cholerae
CAI-1 and AI-2
Biofilm formation
Humans
Rice water diarrhea
Pro-QS
molecules,Turmeric
extract, AHL lactonase
(AiiA)
Vibrio fischeri
N-(3-oxohexanoyl)HSL (LuxI/LuxR)
Bioluminescence and
Colonization
Hawaiian bobtail squid
Symbiosis
Secondary metabolites
of Brown alga
Aeromonas hydrophila
N-butanoyl-HSL
AhyI/AhyR
Serine protease, metallo
protease production
Biofilm formation,
enzyme production
Juvenile and mature fish
and human
Hemorrhagic
septicemia, resulting
in fin and tail rot and
epizootic ulcerative
syndrome Intestinal
and Wound infection
in human
Benzene acetic acid,
Palmitic acid and AHL
lactonase
Aeromonas salmonicida N-butanoyl-HSL
AsaI/AsaR
Exoprotease, cytotoxic
factor
Salmonids
Furunculosis of
salmonids and Ulcer
disease
-
(continued)
A. V. Ravi et al.
Table 1
List of QS systems, signal molecules and identified QSI compounds for aquaculture pathogens (Zhao et al. 2015)
Pathogens
Signal molecules
QS regulated phenotypic
factors
Host organism
Diseases
Reported QSI
compounds
V. harveyi
3-hydroxy-C4-HSL,
AI-2 and CAI-1
Bioluminescence,
Biofilm formation,
Extracellular toxins and
metalloprotease
Shrimp, Abalone, Oyster
and Fish
Luminescent vibriosis,
Skin ulcer, Septicemia
and Gastroenteritis
resulting in mass
mortality
Halogenated furanones,
Cinnamaldehyde,
Brominated
thiophenone, Curcumin,
Boric acid and
Flavonoids and citrus
limonoids
V. cholerae
CAI-1 and AI-2
Biofilm formation
Humans
Rice water diarrhea
Pro-QS
molecules,Turmeric
extract, AHL lactonase
(AiiA)
Vibrio fischeri
N-(3-oxohexanoyl)HSL (LuxI/LuxR)
Bioluminescence and
Colonization
Hawaiian bobtail squid
Symbiosis
Secondary metabolites
of Brown alga
Aeromonas hydrophila
N-butanoyl-HSL
AhyI/AhyR
Serine protease, metallo
protease production
Biofilm formation,
enzyme production
Juvenile and mature fish
and human
Hemorrhagic
septicemia, resulting
in fin and tail rot and
epizootic ulcerative
syndrome Intestinal
and Wound infection
in human
Benzene acetic acid,
Palmitic acid and AHL
lactonase
Aeromonas salmonicida N-butanoyl-HSL
AsaI/AsaR
Exoprotease, cytotoxic
factor
Salmonids
Furunculosis of
salmonids and Ulcer
disease
-
(continued)