Haegebarth A, Clevers H (2009) Wnt signaling, lgr5, and stem cells in the intestine and skin. Am J
Pathol 174:715–721
Hakelien AM, Collas P (2002) Novel approaches to transdifferentiation. Cloning Stem Cells
4:379–387
Hall PE, Lathia JD, Miller NG, Caldwell MA, Ffrench-Constant C (2006) Integrins are markers of
human neural stem cells. Stem Cells 24:2078–2084
Hochedlinger K, Jaenisch R (2002) Nuclear transplantation: lessons from frogs and mice. Curr Opin
Cell Biol 14:741–748
Jennings P. (2015). "The future of in vitro toxicology". Toxicol In Vitro 29:1217-1221.
Kendrick H, Regan JL, Magnay FA, Grigoriadis A, Mitsopoulos C, Zvelebil M, Smalley MJ (2008)
Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of
lineage commitment and cell fate. BMC Genomics 9:591
Kerever ASJ, Vellinga D, Ichikawa N, Moon C, Arikawa-Hirasawa E, Efird JT, Mercier F (2007)
Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor
fibroblast growth factor 2 from the extracellular milieu. Stem Cells 25(9):2146–2157
Kiel MJAM, Radice GL, Morrison SJ (2009) Hematopoietic stem cells do not depend on
N-cadherin to regulate their maintenance. Cell Stem Cell 4:170–179
Krewski D, Acosta D Jr, Andersen M, Anderson H, Bailar JC 3rd, Boekelheide K, Brent R,
Charnley G, Cheung VG, Green S Jr, Kelsey KT, Kerkvliet NI, Li AA, McCray L, Meyer O,
Patterson RD, Pennie W, Scala RA, Solomon GM, Stephens M, Yager J, Zeise L (2008)
Toxicity testing in the 21st century: a vision and a strategy. J Toxicol Environ Health B Crit
Rev 13:51–138
Lane SW, Williams DA, Watt FM (2014) Modulating the stem cell niche for tissue regeneration.
Nat Biotechnol 32:795–803
Lawson DA, Xin L, Lukacs RU, Cheng D, Witte ON (2007) Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci U S A 104:181–186
Le Gall M, Grall D, Chambard JC, Pouyssegur J, Van Obberghen-Schilling E (1998) An anchoragedependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression. Oncogene 17:1271–1277
Liu W, Y Deng, Y Liu, W Gong and W Deng. (2013). Stem cell models for drug discovery and
toxicology studies. J Biochem Mol Toxicol 27:17-27.
Lv FJ, Tuan RS, Cheung KM, Leung VY (2014) Concise review: the surface markers and identity
of human mesenchymal stem cells. Stem Cells 32:1408–1419
Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium
conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78:7634–7638
Marx-Stoelting P (2009) A review of the implementation of the embryonic stem cell test (EST). The
report and recommendations of an ECVAM/ReProTect workshop. Altern Lab Anim
37:313–328
McNeish J (2004) Embryonic stem cells in drug discovery. Nat Rev Drug Discov 3:70–80
Moore KA, Lemischka IR (2006) Stem cells and their niches. Science 311:1880–1885
Moorman A, Webb S, Brown NA, Lamers W, Anderson RH (2003) Development of the heart:
(1) formation of the cardiac chambers and arterial trunks. Heart 89:806–814
Mori H, Hara M (2013) Cultured stem cells as tools for toxicological assays. J Biosci Bioeng
116:647–652
Novak A, Shtrichman R, Germanguz I, Segev H, Zeevi-Levin N, Fishman B, Mandel YE, Barad L,
Domev H, Kotton D, Mostoslavsky G, Binah O, Itskovitz-Eldor J (2010) Enhanced
reprogramming and cardiac differentiation of human keratinocytes derived from plucked hair
follicles, using a single excisable Lentivirus. Cell Reprogram 12:665–678
O’Reilly AM, Lee HH, Simon MA (2008) Integrins control the positioning and proliferation of
follicle stem cells in the Drosophila ovary. J Cell Biol 182:801–815
Ohlstein B, Spradling A (2006) The adult Drosophila posterior midgut is maintained by pluripotent
stem cells. Nature 439:470–474
12 Environmental Interaction and Impact on the Life Span of Stem Cells
263
Pathol 174:715–721
Hakelien AM, Collas P (2002) Novel approaches to transdifferentiation. Cloning Stem Cells
4:379–387
Hall PE, Lathia JD, Miller NG, Caldwell MA, Ffrench-Constant C (2006) Integrins are markers of
human neural stem cells. Stem Cells 24:2078–2084
Hochedlinger K, Jaenisch R (2002) Nuclear transplantation: lessons from frogs and mice. Curr Opin
Cell Biol 14:741–748
Jennings P. (2015). "The future of in vitro toxicology". Toxicol In Vitro 29:1217-1221.
Kendrick H, Regan JL, Magnay FA, Grigoriadis A, Mitsopoulos C, Zvelebil M, Smalley MJ (2008)
Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of
lineage commitment and cell fate. BMC Genomics 9:591
Kerever ASJ, Vellinga D, Ichikawa N, Moon C, Arikawa-Hirasawa E, Efird JT, Mercier F (2007)
Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor
fibroblast growth factor 2 from the extracellular milieu. Stem Cells 25(9):2146–2157
Kiel MJAM, Radice GL, Morrison SJ (2009) Hematopoietic stem cells do not depend on
N-cadherin to regulate their maintenance. Cell Stem Cell 4:170–179
Krewski D, Acosta D Jr, Andersen M, Anderson H, Bailar JC 3rd, Boekelheide K, Brent R,
Charnley G, Cheung VG, Green S Jr, Kelsey KT, Kerkvliet NI, Li AA, McCray L, Meyer O,
Patterson RD, Pennie W, Scala RA, Solomon GM, Stephens M, Yager J, Zeise L (2008)
Toxicity testing in the 21st century: a vision and a strategy. J Toxicol Environ Health B Crit
Rev 13:51–138
Lane SW, Williams DA, Watt FM (2014) Modulating the stem cell niche for tissue regeneration.
Nat Biotechnol 32:795–803
Lawson DA, Xin L, Lukacs RU, Cheng D, Witte ON (2007) Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci U S A 104:181–186
Le Gall M, Grall D, Chambard JC, Pouyssegur J, Van Obberghen-Schilling E (1998) An anchoragedependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression. Oncogene 17:1271–1277
Liu W, Y Deng, Y Liu, W Gong and W Deng. (2013). Stem cell models for drug discovery and
toxicology studies. J Biochem Mol Toxicol 27:17-27.
Lv FJ, Tuan RS, Cheung KM, Leung VY (2014) Concise review: the surface markers and identity
of human mesenchymal stem cells. Stem Cells 32:1408–1419
Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium
conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78:7634–7638
Marx-Stoelting P (2009) A review of the implementation of the embryonic stem cell test (EST). The
report and recommendations of an ECVAM/ReProTect workshop. Altern Lab Anim
37:313–328
McNeish J (2004) Embryonic stem cells in drug discovery. Nat Rev Drug Discov 3:70–80
Moore KA, Lemischka IR (2006) Stem cells and their niches. Science 311:1880–1885
Moorman A, Webb S, Brown NA, Lamers W, Anderson RH (2003) Development of the heart:
(1) formation of the cardiac chambers and arterial trunks. Heart 89:806–814
Mori H, Hara M (2013) Cultured stem cells as tools for toxicological assays. J Biosci Bioeng
116:647–652
Novak A, Shtrichman R, Germanguz I, Segev H, Zeevi-Levin N, Fishman B, Mandel YE, Barad L,
Domev H, Kotton D, Mostoslavsky G, Binah O, Itskovitz-Eldor J (2010) Enhanced
reprogramming and cardiac differentiation of human keratinocytes derived from plucked hair
follicles, using a single excisable Lentivirus. Cell Reprogram 12:665–678
O’Reilly AM, Lee HH, Simon MA (2008) Integrins control the positioning and proliferation of
follicle stem cells in the Drosophila ovary. J Cell Biol 182:801–815
Ohlstein B, Spradling A (2006) The adult Drosophila posterior midgut is maintained by pluripotent
stem cells. Nature 439:470–474
12 Environmental Interaction and Impact on the Life Span of Stem Cells
263