Hoyer LL (2001) The ALS gene family of Candida albicans. Trends Microbiol 9:176–180
Huyer G, Piluek WF, Fansler Z, Kreft SG, Hochstrasser
M, Brodsky JL, Michaelis S (2004) Distinct
machinery is required in Saccharomyces cerevisiae
for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and
a soluble luminal protein. J Biol Chem 279:38369–
38378
Iracane E, Donovan PD, Ola M, Butler G, Holland LM
(2018) Identification of an Exceptionally Long
Intron in the HAC1 Gene of Candida parapsilosis.
mSphere 3
Izawa T, Nagai H, Endo T, Nishikawa S (2012) Yos9p
and Hrd1p mediate ER retention of misfolded
proteins for ER-associated degradation. Mol Biol
Cell 23:1283–1293
Jeenes DJ, Pfaller R, Archer DB (1997) Isolation and
characterisation of a novel stress-inducible PDIfamily gene from Aspergillus niger. Gene 193:151–
156
Jia XM, Wang Y, Jia Y, Gao PH, Xu YG, Wang L, Cao
YY, Cao YB, Zhang LX, Jiang YY (2009) RTA2 is
involved in calcineurin-mediated azole resistance
and sphingoid long-chain base release in Candida
albicans. Cell Mol Life Sci 66:122–134
Joubert A, Simoneau P, Campion C, Bataille-Simoneau
N, Iacomi-Vasilescu B, Poupard P, Francois JM,
Georgeault S, Sellier E, Guillemette T (2011)
Impact of the unfolded protein response on the
pathogenicity of the necrotrophic fungus Alternaria brassicicola. Mol Microbiol 79:1305–1324
Jung KW, Kang HA, Bahn YS (2013) Essential roles of
the Kar2/BiP molecular chaperone downstream of
the UPR pathway in Cryptococcus neoformans.
PLoS One 8:e58956
Jung KW, Lee KT, Averette AF, Hoy MJ, Everitt J, Heitman J, Bahn YS (2018) Evolutionarily conserved
and divergent roles of unfolded protein response
(UPR) in the pathogenic Cryptococcus species
complex. Sci Rep 8:8132
Jung US, Levin DE (1999) Genome-wide analysis of
gene expression regulated by the yeast cell wall
integrity signalling pathway. Mol Microbiol
34:1049–1057
Jung KW, So YS, Bahn YS (2016) Unique roles of the
unfolded protein response pathway in fungal
development and differentiation. Sci Rep 6:33413
Khalid AR, Zhang S, Luo X, Mehmood K, Rahim J,
Shaheen H, Dong P, Qiu D, Ren M (2019) Role of
autophagy-related gene atg22 in developmental
process and virulence of Fusarium oxysporum.
Genes (Basel) 10(5):E365
Kimata Y, Ishiwata-Kimata Y, Ito T, Hirata A, Suzuki T,
Oikawa D, Takeuchi M, Kohno K (2007) Two regulatory steps of ER-stress sensor Ire1 involving its
cluster formation and interaction with unfolded
proteins. J Cell Biol 179:75–86
Kimmig P, Diaz M, Zheng J, Williams CC, Lang A,
Aragon T, Li H, Walter P (2012) The unfolded
protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. elife 1:e00048
Kohno K, Normington K, Sambrook J, Gething MJ,
Mori K (1993) The promoter region of the yeast
KAR2 (BiP) gene contains a regulatory domain
that responds to the presence of unfolded proteins
in the endoplasmic reticulum. Mol Cell Biol
13:877–890
Kong S, Park SY, Lee YH (2015) Systematic characterization of the bZIP transcription factor gene family
in the rice blast fungus, Magnaporthe oryzae.
Environ Microbiol 17:1425–1443
Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J,
Zhang C, Shokat KM, Stroud RM, Walter P (2009)
The unfolded protein response signals through
high-order assembly of Ire1. Nature 457:687–693
Korennykh AV, Korostelev AA, Egea PF, Finer-Moore J,
Stroud RM, Zhang C, Shokat KM, Walter P (2011)
Structural and functional basis for RNA cleavage
by Ire1. BMC Biol 9:47
Kozutsumi Y, Segal M, Normington K, Gething MJ,
Sambrook J (1988) The presence of malfolded
proteins in the endoplasmic reticulum signals the
induction of glucose-regulated proteins. Nature
332:462–464
Krappmann S, Bignell EM, Reichard U, Rogers T,
Haynes K, Braus GH (2004) The Aspergillus fumigatus transcriptional activator CpcA contributes
significantly to the virulence of this fungal pathogen. Mol Microbiol 52:785–799
Krishnan K, Askew DS (2014) The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. Virulence 5:334–340
Krishnan K, Feng X, Powers-Fletcher MV, Bick G,
Richie DL, Woollett LA, Askew DS (2013) Effects
of a defective endoplasmic reticulum-associated
degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the
mold pathogen Aspergillus fumigatus. Eukaryot
Cell 12:512–519
Krishnan K, Ren Z, Losada L, Nierman WC, Lu LJ,
Askew DS (2014) Polysome profiling reveals
broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus
Aspergillus fumigatus. BMC Genomics 15:159
Kwon MJ, Jorgensen TR, Nitsche BM, Arentshorst M,
Park J, Ram AF, Meyer V (2012) The transcriptomic fingerprint of glucoamylase over-expression
in Aspergillus niger. BMC Genomics 13:701
Lanver D, Muller AN, Happel P, Schweizer G, Haas FB,
Franitza M, Pellegrin C, Reissmann S, Altmuller J,
Rensing SA, Kahmann R (2018) The biotrophic
development of Ustilago maydis studied by RNASeq analysis. Plant Cell 30:300–323
72
R. Harting and K. Heimel
Huyer G, Piluek WF, Fansler Z, Kreft SG, Hochstrasser
M, Brodsky JL, Michaelis S (2004) Distinct
machinery is required in Saccharomyces cerevisiae
for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and
a soluble luminal protein. J Biol Chem 279:38369–
38378
Iracane E, Donovan PD, Ola M, Butler G, Holland LM
(2018) Identification of an Exceptionally Long
Intron in the HAC1 Gene of Candida parapsilosis.
mSphere 3
Izawa T, Nagai H, Endo T, Nishikawa S (2012) Yos9p
and Hrd1p mediate ER retention of misfolded
proteins for ER-associated degradation. Mol Biol
Cell 23:1283–1293
Jeenes DJ, Pfaller R, Archer DB (1997) Isolation and
characterisation of a novel stress-inducible PDIfamily gene from Aspergillus niger. Gene 193:151–
156
Jia XM, Wang Y, Jia Y, Gao PH, Xu YG, Wang L, Cao
YY, Cao YB, Zhang LX, Jiang YY (2009) RTA2 is
involved in calcineurin-mediated azole resistance
and sphingoid long-chain base release in Candida
albicans. Cell Mol Life Sci 66:122–134
Joubert A, Simoneau P, Campion C, Bataille-Simoneau
N, Iacomi-Vasilescu B, Poupard P, Francois JM,
Georgeault S, Sellier E, Guillemette T (2011)
Impact of the unfolded protein response on the
pathogenicity of the necrotrophic fungus Alternaria brassicicola. Mol Microbiol 79:1305–1324
Jung KW, Kang HA, Bahn YS (2013) Essential roles of
the Kar2/BiP molecular chaperone downstream of
the UPR pathway in Cryptococcus neoformans.
PLoS One 8:e58956
Jung KW, Lee KT, Averette AF, Hoy MJ, Everitt J, Heitman J, Bahn YS (2018) Evolutionarily conserved
and divergent roles of unfolded protein response
(UPR) in the pathogenic Cryptococcus species
complex. Sci Rep 8:8132
Jung US, Levin DE (1999) Genome-wide analysis of
gene expression regulated by the yeast cell wall
integrity signalling pathway. Mol Microbiol
34:1049–1057
Jung KW, So YS, Bahn YS (2016) Unique roles of the
unfolded protein response pathway in fungal
development and differentiation. Sci Rep 6:33413
Khalid AR, Zhang S, Luo X, Mehmood K, Rahim J,
Shaheen H, Dong P, Qiu D, Ren M (2019) Role of
autophagy-related gene atg22 in developmental
process and virulence of Fusarium oxysporum.
Genes (Basel) 10(5):E365
Kimata Y, Ishiwata-Kimata Y, Ito T, Hirata A, Suzuki T,
Oikawa D, Takeuchi M, Kohno K (2007) Two regulatory steps of ER-stress sensor Ire1 involving its
cluster formation and interaction with unfolded
proteins. J Cell Biol 179:75–86
Kimmig P, Diaz M, Zheng J, Williams CC, Lang A,
Aragon T, Li H, Walter P (2012) The unfolded
protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. elife 1:e00048
Kohno K, Normington K, Sambrook J, Gething MJ,
Mori K (1993) The promoter region of the yeast
KAR2 (BiP) gene contains a regulatory domain
that responds to the presence of unfolded proteins
in the endoplasmic reticulum. Mol Cell Biol
13:877–890
Kong S, Park SY, Lee YH (2015) Systematic characterization of the bZIP transcription factor gene family
in the rice blast fungus, Magnaporthe oryzae.
Environ Microbiol 17:1425–1443
Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J,
Zhang C, Shokat KM, Stroud RM, Walter P (2009)
The unfolded protein response signals through
high-order assembly of Ire1. Nature 457:687–693
Korennykh AV, Korostelev AA, Egea PF, Finer-Moore J,
Stroud RM, Zhang C, Shokat KM, Walter P (2011)
Structural and functional basis for RNA cleavage
by Ire1. BMC Biol 9:47
Kozutsumi Y, Segal M, Normington K, Gething MJ,
Sambrook J (1988) The presence of malfolded
proteins in the endoplasmic reticulum signals the
induction of glucose-regulated proteins. Nature
332:462–464
Krappmann S, Bignell EM, Reichard U, Rogers T,
Haynes K, Braus GH (2004) The Aspergillus fumigatus transcriptional activator CpcA contributes
significantly to the virulence of this fungal pathogen. Mol Microbiol 52:785–799
Krishnan K, Askew DS (2014) The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. Virulence 5:334–340
Krishnan K, Feng X, Powers-Fletcher MV, Bick G,
Richie DL, Woollett LA, Askew DS (2013) Effects
of a defective endoplasmic reticulum-associated
degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the
mold pathogen Aspergillus fumigatus. Eukaryot
Cell 12:512–519
Krishnan K, Ren Z, Losada L, Nierman WC, Lu LJ,
Askew DS (2014) Polysome profiling reveals
broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus
Aspergillus fumigatus. BMC Genomics 15:159
Kwon MJ, Jorgensen TR, Nitsche BM, Arentshorst M,
Park J, Ram AF, Meyer V (2012) The transcriptomic fingerprint of glucoamylase over-expression
in Aspergillus niger. BMC Genomics 13:701
Lanver D, Muller AN, Happel P, Schweizer G, Haas FB,
Franitza M, Pellegrin C, Reissmann S, Altmuller J,
Rensing SA, Kahmann R (2018) The biotrophic
development of Ustilago maydis studied by RNASeq analysis. Plant Cell 30:300–323
72
R. Harting and K. Heimel