91
novel toolbox. In addition, smart catalyst systems based on the development of various ligand-controlled metal catalysts, or special catalyst platform, such as molesieve and metal–organic framework (MOF), will be destined to offer more
opportunities to solve problems and exploit new oxidative coupling reactions with
high regioselectivity and stereoselectivity in the future.
References
1. Dyker G (ed) (2005) Handbook of C-H transformations: applications in organic synthesis,
vol 2. Wiley-VCH, Weinheim
2. Wencel-Delord J, Glorius F (2013) C-H bond activation enables the rapid construction and
late-stage diversification of functional molecules. Nat Chem 5(5):369–375
3. McMurray L, O'Hara F, Gaunt MJ (2011) Recent developments in natural product synthesis
using metal-catalysed C-H bond functionalisation. Chem Soc Rev 40(4):1885–1898
4. Yamaguchi J, Yamaguchi AD, Itami K (2012) C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals. Angew Chem Int Ed 51(36):8960–9009
5. Gutekunst WR, Baran PS (2011) C-H functionalization logic in total synthesis. Chem Soc
Rev 40(4):1976–1991
Scheme 3.70 Pd-catalyzed oxidative borylation of C(sp
3 )–H bonds
3 Oxidative Coupling Reactions Between Hydrocarbons and Organometallic Reagents…
novel toolbox. In addition, smart catalyst systems based on the development of various ligand-controlled metal catalysts, or special catalyst platform, such as molesieve and metal–organic framework (MOF), will be destined to offer more
opportunities to solve problems and exploit new oxidative coupling reactions with
high regioselectivity and stereoselectivity in the future.
References
1. Dyker G (ed) (2005) Handbook of C-H transformations: applications in organic synthesis,
vol 2. Wiley-VCH, Weinheim
2. Wencel-Delord J, Glorius F (2013) C-H bond activation enables the rapid construction and
late-stage diversification of functional molecules. Nat Chem 5(5):369–375
3. McMurray L, O'Hara F, Gaunt MJ (2011) Recent developments in natural product synthesis
using metal-catalysed C-H bond functionalisation. Chem Soc Rev 40(4):1885–1898
4. Yamaguchi J, Yamaguchi AD, Itami K (2012) C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals. Angew Chem Int Ed 51(36):8960–9009
5. Gutekunst WR, Baran PS (2011) C-H functionalization logic in total synthesis. Chem Soc
Rev 40(4):1976–1991
Scheme 3.70 Pd-catalyzed oxidative borylation of C(sp
3 )–H bonds
3 Oxidative Coupling Reactions Between Hydrocarbons and Organometallic Reagents…