X
+
(HO) 2 B R
NiBr 2 (10 mol%)
phen or bpy (20 mol%)
K 3 PO 4 or NaOtBu (2 equiv)
DMAc
120
o
C, 4 h, air
O
N
H
O
N
73%
X = C, N
X
O
N
R
Me
O
N
65%
Me
Ph
O
N
54%
OMe
Ph
O
N
63%
N
Ph
N
O
N
77%
OMe
Ph
N
O
N
47%
Ph
Scheme 3.30 Ni-catalyzed oxidative cross-coupling between heteroarenes and arylboronic acids
Scheme 3.29 Fe-catalyzed oxidative cross-coupling of benzene derivatives with arylboronic
acids