(6)
(7)
(8)
(9)
2.2 Arylation
Since the biaryl structures are prevalent cores in pharmaceutical targets and functional materials [28, 29], the dehydrogenative biaryl coupling of nonfunctionalized
simple arenes has been extensively studied in recent years. Early successful examples with copper salts alone involve the cross-coupling reaction of relatively acidic
1,3-azoles and polyfluoroarenes (Eqs. 10–13) [30–33].
Copper-Mediated Intermolecular C–H/C–H and C–H/N–H Couplings via. . .
51
(7)
(8)
(9)
2.2 Arylation
Since the biaryl structures are prevalent cores in pharmaceutical targets and functional materials [28, 29], the dehydrogenative biaryl coupling of nonfunctionalized
simple arenes has been extensively studied in recent years. Early successful examples with copper salts alone involve the cross-coupling reaction of relatively acidic
1,3-azoles and polyfluoroarenes (Eqs. 10–13) [30–33].
Copper-Mediated Intermolecular C–H/C–H and C–H/N–H Couplings via. . .
51