487
14 Quantitative Structure-Property Relationship Analysis …
The results showed that the third class of benzodiazepines usually contained two
or less S5 fragments and no S2 fragments. Compounds of the second class also contained two or less S5 fragments, S2 fragments, and more than two S76 fragments.
The first class of benzodiazepines had more than two S5 fragments and more than
one S7 fragment. Thus, it seemed to us that the constructed classification tree was
Fig. 14.5 Classification tree for deetermining elimination half-life of substituted benzodiazepines
14 Quantitative Structure-Property Relationship Analysis …
The results showed that the third class of benzodiazepines usually contained two
or less S5 fragments and no S2 fragments. Compounds of the second class also contained two or less S5 fragments, S2 fragments, and more than two S76 fragments.
The first class of benzodiazepines had more than two S5 fragments and more than
one S7 fragment. Thus, it seemed to us that the constructed classification tree was
Fig. 14.5 Classification tree for deetermining elimination half-life of substituted benzodiazepines