91
3 Formation of DNA Lesions, its Prevention and Repair
152. Kerksick C, Willoughby DJ (2005) The anti-oxidant role of glutathione and N-Acetylcysteine supplements and exercise-induced oxidative stress. Int Soc Sport Nutr 2:38–44
153. Galano A, Alvarez-Idaboy JR (2011) Glutathione:mechanism and kinetics of its non-enzymatic defense action against free radicals. RSC Adv 1:1763–1771
154. Alvarez-Idaboy JR, Galano A (2012) On the chemical repair of DNA radicals by glutathione: hydrogen vs electron transfer. J Phys Chem B 116:9316–9325
155. Yadav A, Mishra PC (2013) Modeling the activity of glutathione as a hydroxyl radical
scavenger considering its neutral non-zwitterionic from. J Mol Model 19:767–777
156. Hemat RAS (2003). Principles of Modern Urology, Publisher Urotext (urotext@urotext.
com)
157. Morley N, Curnow A, Salter L, Campbell S, Gould DJ (2003) N-acetyl-l-cysteine prevents
DNA damage induced by UVA, UVB and visible radiation in human fibroblasts. Photochem Photobiol B Biol 72:55–60
158. Aruoma OI, Halliwell B, Hoey BM, Butler J (1989) The anti-oxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous
acid. Free Rad Biol Med 6:593–597
159. Han Y, HaoMiao Z, Shen J (2007) Molecular dynamics simulation study on zwitterionic structure to maintain the normal conformations of glutathione. Sci China Ser Chem B
50:660–664
160. Marenich AV, Cramer CJ, Truhlar DG (2009) Universal solvation model based on solute
electron density and on a continuum model of the solvent defined by the bulk dielectric
constant and atomic surface tensions. J Phys Chem B 113:6378–6396
161. Ehrenshaft M, Bilski P, Li M, Chignell CF, Daub ME (1999) A highly conserved sequence
is a novel gene involved in de novo vitamin B6 biosynthesis. Proc Natl Acad Sci 96:9374–
9378
162. Matxain JM, Ristilä M, Strid Å, Eriksson LA (2006) Theoretical study of the anti-oxidant
properties of pyridoxine. J Phys Chem A 110:13068–13072
163. Matxain JM, Padro D, Ristilä M, Strid Å, Eriksson LA (2009) Evidence of high OH • radical
quenching efficiency by vitamin B 6 . J Phys Chem B 113:9629–9632
164. Ishibashi T, Sato B, Rikitake M, Seo T, Kurokawa R, Hara Y, Naritomi Y, Hara H, Nagao
T (2012) Consumption of water containing a high concentration of molecular hydrogen
reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an openlabel pilot study. Med Gas Res 2:27
165. Agnihotri N, Mishra PC (2009) Mechanism of scavenging action of N-acetylcysteine for
the OH radical: a quantum computational study. J Phys Chem B 113:12096–12104
166. Li P, Shen Z, Wang W, Ma Z, Bi S, Sun H, Bu Y (2010) The capture of H
•
and OH
•
radicals
by vitamin C and implications for the new source for the formation of the anion free radical.
Phys Chem Chem Phys 12:5256–5267
167. Navarrete M, Rangel C, Corchado JC, Espinosa-García J (2005) Trapping of the OH radical
by α-Tocopherol: a theoretical study. J Phys Chem A 109:4777–4784
168. Okada Y, Tanaka K, Fujita I, Sato E, Okajima H (2005) Anti-oxidant activity of thiosulfinates derived from garlic. Redox Rep 10:96–102
169. Vaidya V, Ingold KU, Pratt DA (2009) Garlic: source of the ultimate anti-oxidants-sulfenic
acids. Angew Chem Int Ed 48:157–160
170. Galano A, Francisco-Marquez M (2009) Peroxyl radical scavenging activity of garlic:
2-propenesulfenic acid vs allicin. J Phys Chem B 113:16077–16081
171. Galano A, Francisco-Marquez M (2009) Reactions of OOH radical with β-carotene, lycopene, and torulene: hydrogen atom transfer and adduct formation mechanisms. J Phys
Chem B 113:11338–11345
172. Martínez A, Vargas R, Galano A (2010) Theoretical study on the chemical fate of adducts
formed through free radical addition reactions to carotenoids. Theor Chem Acc 127:595–
603
173. Galano A (2007) Relative antioxidant efficiency of a large series of carotenoids in terms of
one electron transfer reaction. J Phys Chem B 111:12898–12908
3 Formation of DNA Lesions, its Prevention and Repair
152. Kerksick C, Willoughby DJ (2005) The anti-oxidant role of glutathione and N-Acetylcysteine supplements and exercise-induced oxidative stress. Int Soc Sport Nutr 2:38–44
153. Galano A, Alvarez-Idaboy JR (2011) Glutathione:mechanism and kinetics of its non-enzymatic defense action against free radicals. RSC Adv 1:1763–1771
154. Alvarez-Idaboy JR, Galano A (2012) On the chemical repair of DNA radicals by glutathione: hydrogen vs electron transfer. J Phys Chem B 116:9316–9325
155. Yadav A, Mishra PC (2013) Modeling the activity of glutathione as a hydroxyl radical
scavenger considering its neutral non-zwitterionic from. J Mol Model 19:767–777
156. Hemat RAS (2003). Principles of Modern Urology, Publisher Urotext (urotext@urotext.
com)
157. Morley N, Curnow A, Salter L, Campbell S, Gould DJ (2003) N-acetyl-l-cysteine prevents
DNA damage induced by UVA, UVB and visible radiation in human fibroblasts. Photochem Photobiol B Biol 72:55–60
158. Aruoma OI, Halliwell B, Hoey BM, Butler J (1989) The anti-oxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous
acid. Free Rad Biol Med 6:593–597
159. Han Y, HaoMiao Z, Shen J (2007) Molecular dynamics simulation study on zwitterionic structure to maintain the normal conformations of glutathione. Sci China Ser Chem B
50:660–664
160. Marenich AV, Cramer CJ, Truhlar DG (2009) Universal solvation model based on solute
electron density and on a continuum model of the solvent defined by the bulk dielectric
constant and atomic surface tensions. J Phys Chem B 113:6378–6396
161. Ehrenshaft M, Bilski P, Li M, Chignell CF, Daub ME (1999) A highly conserved sequence
is a novel gene involved in de novo vitamin B6 biosynthesis. Proc Natl Acad Sci 96:9374–
9378
162. Matxain JM, Ristilä M, Strid Å, Eriksson LA (2006) Theoretical study of the anti-oxidant
properties of pyridoxine. J Phys Chem A 110:13068–13072
163. Matxain JM, Padro D, Ristilä M, Strid Å, Eriksson LA (2009) Evidence of high OH • radical
quenching efficiency by vitamin B 6 . J Phys Chem B 113:9629–9632
164. Ishibashi T, Sato B, Rikitake M, Seo T, Kurokawa R, Hara Y, Naritomi Y, Hara H, Nagao
T (2012) Consumption of water containing a high concentration of molecular hydrogen
reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an openlabel pilot study. Med Gas Res 2:27
165. Agnihotri N, Mishra PC (2009) Mechanism of scavenging action of N-acetylcysteine for
the OH radical: a quantum computational study. J Phys Chem B 113:12096–12104
166. Li P, Shen Z, Wang W, Ma Z, Bi S, Sun H, Bu Y (2010) The capture of H
•
and OH
•
radicals
by vitamin C and implications for the new source for the formation of the anion free radical.
Phys Chem Chem Phys 12:5256–5267
167. Navarrete M, Rangel C, Corchado JC, Espinosa-García J (2005) Trapping of the OH radical
by α-Tocopherol: a theoretical study. J Phys Chem A 109:4777–4784
168. Okada Y, Tanaka K, Fujita I, Sato E, Okajima H (2005) Anti-oxidant activity of thiosulfinates derived from garlic. Redox Rep 10:96–102
169. Vaidya V, Ingold KU, Pratt DA (2009) Garlic: source of the ultimate anti-oxidants-sulfenic
acids. Angew Chem Int Ed 48:157–160
170. Galano A, Francisco-Marquez M (2009) Peroxyl radical scavenging activity of garlic:
2-propenesulfenic acid vs allicin. J Phys Chem B 113:16077–16081
171. Galano A, Francisco-Marquez M (2009) Reactions of OOH radical with β-carotene, lycopene, and torulene: hydrogen atom transfer and adduct formation mechanisms. J Phys
Chem B 113:11338–11345
172. Martínez A, Vargas R, Galano A (2010) Theoretical study on the chemical fate of adducts
formed through free radical addition reactions to carotenoids. Theor Chem Acc 127:595–
603
173. Galano A (2007) Relative antioxidant efficiency of a large series of carotenoids in terms of
one electron transfer reaction. J Phys Chem B 111:12898–12908