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L. Pan and X. Chen
Fig. 12.10 Statistical correlation analysis between the Automated method GS-GC and manual
tracings Manual 1. a Linear regression analysis results comparing SEAD volumes. b Bland-Altman
plots
more accurate segmentation result. The similar idea has also been proved in [42].
The proposed graph-theoretic based method effectively combined the GS and GC
methods for segmenting the layers and SEADs simultaneously. An automatic voxel
classification-based method was used for initialization which was based on the layerspecific texture features following the success of our previous work [14, 31]. The later
GS- GC method effectively integrate the probability constraints from the initialization
which further improved the segmentation accuracy.
12.5.3 Limitations of the Reported Method
This graph-theoretic based method approach has some limitations. The first limitation
is that it largely relies on the initialization results. If the probability constraints from
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