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6.3.4 Compatibility with Instrumental Detection Systems
An extraction technique is useless without an appropriate detection method for the
target compound. Therefore, a high advantage of using deep eutectic solvent in the
extraction techniques is the absence of interference generally observed for these
solvents with the detection methods. They showed a high compatibility with various
instrumental detection systems such as mass spectrometry, flame ionization detector, UV-Vis spectroscopy, inductively coupled plasma-optical emission spectrometry, diode array detector, graphite furnace atomic absorption spectroscopy, Fourier
transform infrared spectroscopy, and fluorescence; therefore, new combinations
with advanced separation techniques like high-performance liquid chromatography,
gas chromatography, and thin-layer chromatography are ongoing, for example, by
using a certain percentage of deep eutectic solvent in the mobile phase (Tan
et al. 2016).
6.3.5 Surface Tension
Surface tension depends on the strength of intermolecular interaction of deep eutectic solvent and on temperature (Tang et al. 2014). Therefore, it is positively dependent on the viscosity. Some deep eutectic solvent (for example, choline chloride/
glycerol) showed a linear correlation between the surface tension and the
Fig. 6.17 Density (ρ) of the choline chloride/glycerol deep eutectic solvent as a function of choline chloride (ChCl) percentage. Addition of ChCl to glycerol results in a decrease of the deep
eutectic solvent density. (Figure reprinted with permission from Abbott et al. 2011)
6 Methods for Extraction of Bioactive Compounds from Plant and Animal Matter…
6.3.4 Compatibility with Instrumental Detection Systems
An extraction technique is useless without an appropriate detection method for the
target compound. Therefore, a high advantage of using deep eutectic solvent in the
extraction techniques is the absence of interference generally observed for these
solvents with the detection methods. They showed a high compatibility with various
instrumental detection systems such as mass spectrometry, flame ionization detector, UV-Vis spectroscopy, inductively coupled plasma-optical emission spectrometry, diode array detector, graphite furnace atomic absorption spectroscopy, Fourier
transform infrared spectroscopy, and fluorescence; therefore, new combinations
with advanced separation techniques like high-performance liquid chromatography,
gas chromatography, and thin-layer chromatography are ongoing, for example, by
using a certain percentage of deep eutectic solvent in the mobile phase (Tan
et al. 2016).
6.3.5 Surface Tension
Surface tension depends on the strength of intermolecular interaction of deep eutectic solvent and on temperature (Tang et al. 2014). Therefore, it is positively dependent on the viscosity. Some deep eutectic solvent (for example, choline chloride/
glycerol) showed a linear correlation between the surface tension and the
Fig. 6.17 Density (ρ) of the choline chloride/glycerol deep eutectic solvent as a function of choline chloride (ChCl) percentage. Addition of ChCl to glycerol results in a decrease of the deep
eutectic solvent density. (Figure reprinted with permission from Abbott et al. 2011)
6 Methods for Extraction of Bioactive Compounds from Plant and Animal Matter…