98
Jeliński T, Przybyłek M, Cysewski P (2019b) Natural deep eutectic solvents as agents for improving solubility, stability and delivery of curcumin. Pharm Res 36:116. https://doi.org/10.1007/
s11095-019-2643-2
Juneidi I, Hayyan M, Mohd Ali O (2016) Toxicity profile of choline chloride-based deep eutectic
solvents for fungi and Cyprinus carpio fish. Environ Sci Pollut Res Int 23:7648–7659. https://
doi.org/10.1007/s11356-015-6003-4
Kellar R, Nieto NC, Koppisch A, Del Sesto R (2018) Ionic liquids that sterilize and prevent biofilm
formation in skin wound healing devices. US20180093011
Khodaverdian S, Dabirmanesh B, Heydari A, Dashtban-Moghadam E, Khajeh K, Ghazi F (2018)
Activity, stability and structure of laccase in betaine based natural deep eutectic solvents. Int J
Biol Macromol 107:2574–2579. https://doi.org/10.1016/j.ijbiomac.2017.10.144
Lee MS, Lee K, Nam MW, Jeong KM, Lee JE, Kim NW, Yin Y, Lim SY, Yoo DE, Lee J, Jeong JH
(2018) Natural deep eutectic solvents as a storage medium for human interferon-α2: a green
and improved strategy for room-temperature biologics. J Ind Eng Chem 65:343–348. https://
doi.org/10.1016/j.jiec.2018.05.005
Li Z, Lee PI (2016) Investigation on drug solubility enhancement using deep eutectic solvents
and their derivatives. Int J Pharm 505:283–288. https://doi.org/10.1016/j.ijpharm.2016.04.018
Li Y, Wu X, Zhu Q, Chen Z, Lu Y, Qi J, Wu W (2019) Improving the hypoglycemic effect of insulin via the nasal administration of deep eutectic solvents. Int J Pharm 569:118584. https://doi.
org/10.1016/j.ijpharm.2019.118584
Lim JH, Song SH, Park HS, Lee JR, Lee SM (2017) Spontaneous detachment of Streptococcus
mutans biofilm by synergistic effect between zwitterion and sugar alcohol. Sci Rep 7:8107.
https://doi.org/10.1038/s41598-017-08558-x
Lim JH, Jeong Y, Song SH, Ahn JH, Lee JR, Lee SM (2018) Penetration of an antimicrobial
zinc-sugar alcohol complex into Streptococcus mutans biofilms. Sci Rep 8:16154. https://doi.
org/10.1038/s41598-018-34366-y
Lu C, Cao J, Wang N, Su E (2016) Significantly improving the solubility of non-steroidal antiinflammatory drugs in deep eutectic solvents for potential non-aqueous liquid administration.
Med Chem Commun 7:955–959. https://doi.org/10.1039/C5MD00551E
Macário IPE, Jesus F, Pereira JL, Ventura SPM, Gonçalves AMM, Coutinho JAP, Gonçalves FJM
(2018a) Unraveling the ecotoxicity of deep eutectic solvents using the mixture toxicity theory.
Chemosphere 212:890–897. https://doi.org/10.1016/j.chemosphere.2018.08.153
Macário IPE, Ventura SPM, Pereira JL, Gonçalves AMM, Coutinho JAP, Gonçalves FJM (2018b)
The antagonist and synergist potential of cholinium-based deep eutectic solvents. Ecotoxicol
Environ Saf 165:597–602. https://doi.org/10.1016/j.ecoenv.2018.09.027
Macário IPE, Oliveira H, Menezes AC, Ventura SPM, Pereira JL, Gonçalves AMM, Coutinho JAP,
Gonçalves FJM (2019) Cytotoxicity profiling of deep eutectic solvents to human skin cells. Sci
Rep 9:3932. https://doi.org/10.1038/s41598-019-39910-y
Mamashli F, Badraghi J, Delavari B, Lanjanian H, Sabbaghian M, Hosseini M, Saboury AA (2018)
Improvement of versatile peroxidase activity and stability by a cholinium-based ionic liquid. J
Mol Liq 272:597–608. https://doi.org/10.1016/j.molliq.2018.09.128
Mao S, Li K, Hou Y, Liu Y, Ji S, Qin H, Lu F (2018) Synergistic effects of components in deep
eutectic solvents relieve toxicity and improve the performance of steroid biotransformation
catalyzed by Arthrobacter simplex. J Chem Technol Biotechnol 93:2729–2736. https://doi.
org/10.1002/jctb.5629
Mbous YP, Hayyan M, Wong WF, Looi CY, Hashim MA (2017) Unraveling the cytotoxicity and
metabolic pathways of binary natural deep eutectic solvent systems. Sci Rep 7:41257. https://
doi.org/10.1038/srep41257
McCune JA, Kunz S, Olesińska M, Scherman OA (2017) DESolution of CD and CB macrocycles.
Chem Eur J 23:8601–8604. https://doi.org/10.1002/chem.201701275
Mitar A, Panić M, Prlić Kardum J, Halambek J, Sander A, Zagajski Kučan K, Radojčić
Redovniković I, Radošević K (2019) Physicochemical properties, cytotoxicity, and
antioxidative activity of natural deep eutectic solvents containing organic acid. Chem
Biochem Eng Q 33:1–18. https://doi.org/10.15255/CABEQ.2018.1454
C.-H. Nguyen et al.
Jeliński T, Przybyłek M, Cysewski P (2019b) Natural deep eutectic solvents as agents for improving solubility, stability and delivery of curcumin. Pharm Res 36:116. https://doi.org/10.1007/
s11095-019-2643-2
Juneidi I, Hayyan M, Mohd Ali O (2016) Toxicity profile of choline chloride-based deep eutectic
solvents for fungi and Cyprinus carpio fish. Environ Sci Pollut Res Int 23:7648–7659. https://
doi.org/10.1007/s11356-015-6003-4
Kellar R, Nieto NC, Koppisch A, Del Sesto R (2018) Ionic liquids that sterilize and prevent biofilm
formation in skin wound healing devices. US20180093011
Khodaverdian S, Dabirmanesh B, Heydari A, Dashtban-Moghadam E, Khajeh K, Ghazi F (2018)
Activity, stability and structure of laccase in betaine based natural deep eutectic solvents. Int J
Biol Macromol 107:2574–2579. https://doi.org/10.1016/j.ijbiomac.2017.10.144
Lee MS, Lee K, Nam MW, Jeong KM, Lee JE, Kim NW, Yin Y, Lim SY, Yoo DE, Lee J, Jeong JH
(2018) Natural deep eutectic solvents as a storage medium for human interferon-α2: a green
and improved strategy for room-temperature biologics. J Ind Eng Chem 65:343–348. https://
doi.org/10.1016/j.jiec.2018.05.005
Li Z, Lee PI (2016) Investigation on drug solubility enhancement using deep eutectic solvents
and their derivatives. Int J Pharm 505:283–288. https://doi.org/10.1016/j.ijpharm.2016.04.018
Li Y, Wu X, Zhu Q, Chen Z, Lu Y, Qi J, Wu W (2019) Improving the hypoglycemic effect of insulin via the nasal administration of deep eutectic solvents. Int J Pharm 569:118584. https://doi.
org/10.1016/j.ijpharm.2019.118584
Lim JH, Song SH, Park HS, Lee JR, Lee SM (2017) Spontaneous detachment of Streptococcus
mutans biofilm by synergistic effect between zwitterion and sugar alcohol. Sci Rep 7:8107.
https://doi.org/10.1038/s41598-017-08558-x
Lim JH, Jeong Y, Song SH, Ahn JH, Lee JR, Lee SM (2018) Penetration of an antimicrobial
zinc-sugar alcohol complex into Streptococcus mutans biofilms. Sci Rep 8:16154. https://doi.
org/10.1038/s41598-018-34366-y
Lu C, Cao J, Wang N, Su E (2016) Significantly improving the solubility of non-steroidal antiinflammatory drugs in deep eutectic solvents for potential non-aqueous liquid administration.
Med Chem Commun 7:955–959. https://doi.org/10.1039/C5MD00551E
Macário IPE, Jesus F, Pereira JL, Ventura SPM, Gonçalves AMM, Coutinho JAP, Gonçalves FJM
(2018a) Unraveling the ecotoxicity of deep eutectic solvents using the mixture toxicity theory.
Chemosphere 212:890–897. https://doi.org/10.1016/j.chemosphere.2018.08.153
Macário IPE, Ventura SPM, Pereira JL, Gonçalves AMM, Coutinho JAP, Gonçalves FJM (2018b)
The antagonist and synergist potential of cholinium-based deep eutectic solvents. Ecotoxicol
Environ Saf 165:597–602. https://doi.org/10.1016/j.ecoenv.2018.09.027
Macário IPE, Oliveira H, Menezes AC, Ventura SPM, Pereira JL, Gonçalves AMM, Coutinho JAP,
Gonçalves FJM (2019) Cytotoxicity profiling of deep eutectic solvents to human skin cells. Sci
Rep 9:3932. https://doi.org/10.1038/s41598-019-39910-y
Mamashli F, Badraghi J, Delavari B, Lanjanian H, Sabbaghian M, Hosseini M, Saboury AA (2018)
Improvement of versatile peroxidase activity and stability by a cholinium-based ionic liquid. J
Mol Liq 272:597–608. https://doi.org/10.1016/j.molliq.2018.09.128
Mao S, Li K, Hou Y, Liu Y, Ji S, Qin H, Lu F (2018) Synergistic effects of components in deep
eutectic solvents relieve toxicity and improve the performance of steroid biotransformation
catalyzed by Arthrobacter simplex. J Chem Technol Biotechnol 93:2729–2736. https://doi.
org/10.1002/jctb.5629
Mbous YP, Hayyan M, Wong WF, Looi CY, Hashim MA (2017) Unraveling the cytotoxicity and
metabolic pathways of binary natural deep eutectic solvent systems. Sci Rep 7:41257. https://
doi.org/10.1038/srep41257
McCune JA, Kunz S, Olesińska M, Scherman OA (2017) DESolution of CD and CB macrocycles.
Chem Eur J 23:8601–8604. https://doi.org/10.1002/chem.201701275
Mitar A, Panić M, Prlić Kardum J, Halambek J, Sander A, Zagajski Kučan K, Radojčić
Redovniković I, Radošević K (2019) Physicochemical properties, cytotoxicity, and
antioxidative activity of natural deep eutectic solvents containing organic acid. Chem
Biochem Eng Q 33:1–18. https://doi.org/10.15255/CABEQ.2018.1454
C.-H. Nguyen et al.