320
Table 7.1 (continued)
Polymer
Cyclodextrin
Pharmaceuticals
Technique
Outcomes offered by
cyclodextrin-based polymeric
nanoparticles
Reference
Chitosan
Carboxymethyl-βcyclodextrin
Sulindac
Ionotropic gelation technique
Encapsulation of sulindac and
continuous release of the drug
throughput 24 h
Ammar et al.
(2012)
Chitosan
Sulfobutylether-βcyclodextrin
Econazole nitrate
Ionotropic gelation technique
Controlled delivery of drug to
the eye
Mahmoud
et al. (2011)
Chitosan
Carboxymethyl-βcyclodextrin
Indomethacin
–
Controlled drug release and
biodegradability
Anirudhan
et al. (2013)
Chitosan
toluenesulfonyl)-βcyclodextrin
Ketoprofen
Ionic gelation technique
Controlled release of poorly
water-soluble drugs with
pH-responsive capability
Yuan et al.
(2013)
Chitosan
Sulfobutylether-βcyclodextrin
Quercetin
Conotropic gelation technique Anti-quorum sensing or
antibacterial activities
Nguyen and
Goycoolea
(2017)
N-maleoyl chitosan
β-Cyclodextrin
Ketoprofen
Ionic gelation method
Sustained release of poorly
water-soluble drugs
Hou et al.
(2017)
Chitosan
β-Cyclodextrin
Carvacrol and
linalool
Kneading method
A promising carrier for
botanical pesticides
Campos et al.
(2018)
Chitosan
β-Cyclodextrin
Ovalbumin
Precipitation/coacervation
method
A promising antigen delivery
system for oral vaccination
He et al.
(2019)
Polyethylene glycol
and polyethylenimine
β-Cyclodextrin
5-Fluorouracil
Anticancer drug delivery in
tumor therapy.
Prabha and
Raj (2016)
Polyethylene glycol
Amphiphilic cyclodextrins Short interfering
RNA
Improved stability and
reduced clearance
Godinho et al.
(2014)
Polyethylene glycol
Modified
β-cyclodextrin
and derivatives
Short interfering
RNA
Efficient cellular uptake,
gene-knockdown ability
Gooding et al.
(2015)
A. Pandey
Table 7.1 (continued)
Polymer
Cyclodextrin
Pharmaceuticals
Technique
Outcomes offered by
cyclodextrin-based polymeric
nanoparticles
Reference
Chitosan
Carboxymethyl-βcyclodextrin
Sulindac
Ionotropic gelation technique
Encapsulation of sulindac and
continuous release of the drug
throughput 24 h
Ammar et al.
(2012)
Chitosan
Sulfobutylether-βcyclodextrin
Econazole nitrate
Ionotropic gelation technique
Controlled delivery of drug to
the eye
Mahmoud
et al. (2011)
Chitosan
Carboxymethyl-βcyclodextrin
Indomethacin
–
Controlled drug release and
biodegradability
Anirudhan
et al. (2013)
Chitosan
toluenesulfonyl)-βcyclodextrin
Ketoprofen
Ionic gelation technique
Controlled release of poorly
water-soluble drugs with
pH-responsive capability
Yuan et al.
(2013)
Chitosan
Sulfobutylether-βcyclodextrin
Quercetin
Conotropic gelation technique Anti-quorum sensing or
antibacterial activities
Nguyen and
Goycoolea
(2017)
N-maleoyl chitosan
β-Cyclodextrin
Ketoprofen
Ionic gelation method
Sustained release of poorly
water-soluble drugs
Hou et al.
(2017)
Chitosan
β-Cyclodextrin
Carvacrol and
linalool
Kneading method
A promising carrier for
botanical pesticides
Campos et al.
(2018)
Chitosan
β-Cyclodextrin
Ovalbumin
Precipitation/coacervation
method
A promising antigen delivery
system for oral vaccination
He et al.
(2019)
Polyethylene glycol
and polyethylenimine
β-Cyclodextrin
5-Fluorouracil
Anticancer drug delivery in
tumor therapy.
Prabha and
Raj (2016)
Polyethylene glycol
Amphiphilic cyclodextrins Short interfering
RNA
Improved stability and
reduced clearance
Godinho et al.
(2014)
Polyethylene glycol
Modified
β-cyclodextrin
and derivatives
Short interfering
RNA
Efficient cellular uptake,
gene-knockdown ability
Gooding et al.
(2015)
A. Pandey
