176
References
Ahmed SM, Casu B, Cedro A, Guerrini M, Lanzarotti E, Moltrasion D, Naggi AM, Torri G
(1994) Disruption of micellar aggregates of ganglioside GM-1 by complexation with alphacyclodextrin. Int J Pharm 109:99–106. https://doi.org/10.1016/0378-5173(94)90137-6
Casu B (1964) Spectrometric identification of organic compounds. Chim L’Ind 46:1425–1429
Casu B (1966) Recent contributions to knowledge of amylose and cyclodextrins structure. Chim
L’Ind 48:921–923
Casu B (1967) Recenti contributi alla conoscenza della struttura dell amilosio e delle ciclodestrine.
Chim L’Ind 49:81–83
Casu B (1968a) Conformazione e proprietà di inclusion dell’amilosio di suoi oligomeri e di loro
derivati. Consiglio Nazionale delle Ricerche, La Ricerca Scientifica, Roma, pp 303–312
Casu B (1968b) Chemistry of macromolecules. Ital Res Counc Spec Publ 8:309–311
Casu B (1980) IR, RAMAN and NMR characterization of substances of pharmaceutical and biological interest in aqueous solution. Chim L’Ind 62:215–221
Casu B (1981) New developments in polysaccharide research and utilization (Milan, Italy, 22–23
May 1980). Enzym Microb Technol 3:275–275. https://doi.org/10.1016/0141-0229(81)90101-0
Casu B (1982) Structure and conformation of polysaccharides by NMR spectroscopy. Carbohydr
Polym 2:247–253. https://doi.org/10.1016/0144-8617(82)90026-1
Casu B (1985a) Chapter 1: Nuclear magnetic resonance studies of polysaccharide structure
and interactions. In: EDT A (ed) Polysaccharides – topics in structure and morphology. The
MacMillan Press LTD, London, pp 1–40. ISBN: 978-1-349-06369-7
Casu B (1985b) Structure and biological activity of heparin. Adv Carbohydr Chem Biochem
43:51–134. https://doi.org/10.1016/S0065-2318(08)60067-0
Casu B (1986) Trends in the development of oligo- and polysaccharides of medical interest. In:
Stivala SS, Crescenzi V, Dea M (eds) Industrial polysaccharides. The impact of biotechnology
and advanced methodologies. Gordon and Breach, New York, pp 189–193
Casu B (1987) Structure and inclusion properties of cyclodextrins. Chimicaoggi:23–25
Table 3.1 (continued)
Year Result
1988 A comprehensive study of the interaction of cyclodextrins with neutral glycolipids
Cyclodextrin molecules are able to form inclusion complexes with long hydrophobic
chains of surfactant molecules
The NMR spectra of cyclodextrin change in the presence of the glycolipid not only with
shifts of the H-3 and H-5 signals, those usually affected by formation of inclusion
complexes, but also with involvement of other signals, e.g., shift of H-2 and H-4 groups
1990 The first demonstration that α-cyclodextrin can disrupt the microaggregates of
alkylglycosides in aqueous solutions: the NMR parameters sensitively reflect the
interaction of cyclodextrins with these amphiphilic molecules
Cyclodextrins can control the aggregation and surfactant properties of amphiphilic
substances
1992 Further evidence that cyclodextrins can disrupt micellar aggregates of glycolipids are
obtained through ultrafiltration experiments
1994 Confirmation that micellar aggregates of glycolipid can be disrupted by the formation of
inclusion complexes only with α-cyclodextrin
β-cyclodextrin gives weaker complexes with glycolipid but does not produce any
significant disaggregation effects
Fully methylated β-cyclodextrin and hydroxyethyl-β-cyclodextrin are also ineffective
G. Torri et al.
References
Ahmed SM, Casu B, Cedro A, Guerrini M, Lanzarotti E, Moltrasion D, Naggi AM, Torri G
(1994) Disruption of micellar aggregates of ganglioside GM-1 by complexation with alphacyclodextrin. Int J Pharm 109:99–106. https://doi.org/10.1016/0378-5173(94)90137-6
Casu B (1964) Spectrometric identification of organic compounds. Chim L’Ind 46:1425–1429
Casu B (1966) Recent contributions to knowledge of amylose and cyclodextrins structure. Chim
L’Ind 48:921–923
Casu B (1967) Recenti contributi alla conoscenza della struttura dell amilosio e delle ciclodestrine.
Chim L’Ind 49:81–83
Casu B (1968a) Conformazione e proprietà di inclusion dell’amilosio di suoi oligomeri e di loro
derivati. Consiglio Nazionale delle Ricerche, La Ricerca Scientifica, Roma, pp 303–312
Casu B (1968b) Chemistry of macromolecules. Ital Res Counc Spec Publ 8:309–311
Casu B (1980) IR, RAMAN and NMR characterization of substances of pharmaceutical and biological interest in aqueous solution. Chim L’Ind 62:215–221
Casu B (1981) New developments in polysaccharide research and utilization (Milan, Italy, 22–23
May 1980). Enzym Microb Technol 3:275–275. https://doi.org/10.1016/0141-0229(81)90101-0
Casu B (1982) Structure and conformation of polysaccharides by NMR spectroscopy. Carbohydr
Polym 2:247–253. https://doi.org/10.1016/0144-8617(82)90026-1
Casu B (1985a) Chapter 1: Nuclear magnetic resonance studies of polysaccharide structure
and interactions. In: EDT A (ed) Polysaccharides – topics in structure and morphology. The
MacMillan Press LTD, London, pp 1–40. ISBN: 978-1-349-06369-7
Casu B (1985b) Structure and biological activity of heparin. Adv Carbohydr Chem Biochem
43:51–134. https://doi.org/10.1016/S0065-2318(08)60067-0
Casu B (1986) Trends in the development of oligo- and polysaccharides of medical interest. In:
Stivala SS, Crescenzi V, Dea M (eds) Industrial polysaccharides. The impact of biotechnology
and advanced methodologies. Gordon and Breach, New York, pp 189–193
Casu B (1987) Structure and inclusion properties of cyclodextrins. Chimicaoggi:23–25
Table 3.1 (continued)
Year Result
1988 A comprehensive study of the interaction of cyclodextrins with neutral glycolipids
Cyclodextrin molecules are able to form inclusion complexes with long hydrophobic
chains of surfactant molecules
The NMR spectra of cyclodextrin change in the presence of the glycolipid not only with
shifts of the H-3 and H-5 signals, those usually affected by formation of inclusion
complexes, but also with involvement of other signals, e.g., shift of H-2 and H-4 groups
1990 The first demonstration that α-cyclodextrin can disrupt the microaggregates of
alkylglycosides in aqueous solutions: the NMR parameters sensitively reflect the
interaction of cyclodextrins with these amphiphilic molecules
Cyclodextrins can control the aggregation and surfactant properties of amphiphilic
substances
1992 Further evidence that cyclodextrins can disrupt micellar aggregates of glycolipids are
obtained through ultrafiltration experiments
1994 Confirmation that micellar aggregates of glycolipid can be disrupted by the formation of
inclusion complexes only with α-cyclodextrin
β-cyclodextrin gives weaker complexes with glycolipid but does not produce any
significant disaggregation effects
Fully methylated β-cyclodextrin and hydroxyethyl-β-cyclodextrin are also ineffective
G. Torri et al.