134
Later, the capillary electrophoresis technique was developed for enantioseparation of racemic mixtures using various cyclodextrin derivatives as chiral selectors
(Szemán et al. 1996; Iványi et al. 2004). Professor Szejtli has recognized the importance of this, at that time novel, technique. CycloLab was among the first in Hungary
Table 2.6 Applications of cyclodextrins in chromatographic methods (MP mobile phase; SP
stationary phase)
Cyclodextrins
Thin
layer
Gasliquid
Gassolid
Gel
inclusion
Highperformance
liquid
Affinity Electrokinetic
Native
MP
SP
SP
MP
MP
Modified
MP
SP
SP
MP
MP
Soluble
polymers
MP
Insoluble
polymers
SP
SP
SP
Immobilized
SP
SP
SP
Fig. 2.22 Separation of the enantiomers of racemic vincadifformine by passing its aqueous solution through a β-cyclodextrin-polymer column. (Source: CycloLab archives)
G. Crini et al.
Later, the capillary electrophoresis technique was developed for enantioseparation of racemic mixtures using various cyclodextrin derivatives as chiral selectors
(Szemán et al. 1996; Iványi et al. 2004). Professor Szejtli has recognized the importance of this, at that time novel, technique. CycloLab was among the first in Hungary
Table 2.6 Applications of cyclodextrins in chromatographic methods (MP mobile phase; SP
stationary phase)
Cyclodextrins
Thin
layer
Gasliquid
Gassolid
Gel
inclusion
Highperformance
liquid
Affinity Electrokinetic
Native
MP
SP
SP
MP
MP
Modified
MP
SP
SP
MP
MP
Soluble
polymers
MP
Insoluble
polymers
SP
SP
SP
Immobilized
SP
SP
SP
Fig. 2.22 Separation of the enantiomers of racemic vincadifformine by passing its aqueous solution through a β-cyclodextrin-polymer column. (Source: CycloLab archives)
G. Crini et al.