101. Bhatia S, Mohr A, Mathur D, Parmar VS, Haag R, Prasad AK (2011) Biocatalytic route to
sugar-PEG-based polymers for drug delivery applications. Biomacromolecules
12:3487–3498
102. Wang H-Y, Zhou Y-J, Wang Z, Wang N, Li K, Yu X-Q (2011) Enzyme-catalyzed synthesis
of a novel thermosensitive polyester with pendant ketoprofen. Macromol Biosci 11:595–599
103. Wang W, Tudryn GJ, Colby RH, Winey KI (2011) Thermally driven ionic aggregation in
poly(ethylene oxide)-based sulfonate ionomers. J Am Chem Soc 133:10826–10831
104. Braunova ´ A, Pechar M, Ulbrich K (2004) Degradation behavior of poly(ethylene glycol)
diblock and multiblock polymers with hydrolytically degradable ester linkages. Collect
Czech Chem Commun 69:1643–1656
105. Lee Y, Koo H, G-w J, Mo H, Cho MY, Park J-Y, Choi JS, Park JS (2005) Poly(ethylene oxide
sulfide): new poly(ethylene glycol) derivatives degradable in reductive conditions.
Biomacromolecules 6:24–26
106. Lee J, Joo MK, Kim J, Park JS, Yoon M-Y, Jeong B (2009) Temperature-sensitive biodegradable poly(ethylene glycol). J Biomater Sci Polym Ed 20:957–965
107. Etrych T, Kova ´r L, S ˇ ubr V, Braunova ´ A, Pechar M, Chytil P, R ˇ ı
´hova ´ B, Ulbrich K (2010)
High-molecular-weight polymers containing biodegradable disulfide bonds: synthesis and
in vitro verification of intracellular degradation. J Bioact Compat Polym 25:5–26
108. Hernandez-Mireles T, Rito-Palomares M (2006) New aqueous two-phase systems based on
poly(ethylene oxide sulfide) (PEOS) and potassium phosphate for the potential recovery of
proteins. J Chem Technol Biotechnol 81:997–1002
109. Reid B, Tzeng S, Warren A, Kozielski K, Elisseeff J (2010) Development of a PEG derivative
containing hydrolytically degradable hemiacetals. Macromolecules 43:9588–9590
110. Qi M, Li X, Yang Y, Zhou S (2008) Electrospun fibers of acid-labile biodegradable polymers
containing ortho ester groups for controlled release of paracetamol. Eur J Pharm Biopharm
70:445–452
111. Ulbrich K, Strohalm J, Kopec ˇek J (1986) Poly(ethylene glycol)s containing enzymatically
degradable bonds. Makromol Chem 187:1131–1144
112. Pechar M, Strohalm J, Ulbrich K (1995) Synthesis of poly(ethylene glycol) block copolymers
as potential water-soluble drug carriers. Collect Czech Chem Commun 60:1765–1780
113. Pechar M, Strohalm J, Ulbrich K, Schacht E (1997) Biodegradable drug carriers based on
poly(ethylene glycol) block copolymers. Macromol Chem Phys 198:1009–1020
114. Ulbrich K, Pechar M, Strohalm J, S ˇ ubr V, R ˇ ı
´hova ´ B (1997) Polymeric carriers of drugs for
site-specific therapy. Macromol Symp 118:577–585
115. Ulbrich K, S ˇ ubr V, Pechar M, Strohalm J, Jelı ´nkova ´ M, R ˇ ı
´hova ´ B (2000) Hydrophilic
polymers for drug delivery. Macromol Symp 152:151–162
116. Pechar M, Ulbrich K, S ˇ ubr V, Seymour LW, Schacht EH (2000) Poly(ethylene glycol)
multiblock copolymer as a carrier of anti-cancer drug doxorubicin. Bioconjugate Chem
11:131–139
117. Pechar M, Ulbrich K, Jelı ´nkova ´ M, R ˇ ı
´hova ´ B (2003) Conjugates of antibody-targeted PEG
multiblock polymers with doxorubicin in cancer therapy. Macromol Biosci 3:364–372
118. Pechar M, Braunova ´ A, Ulbrich K, Jelı ´nkova ´ M, R ˇ ı
´hova ´ B (2005) Poly(Ethylene Glycol)doxorubicin conjugates with pH-controlled activation. J Bioact Compat Polym 20:319–341
119. Pechar M, Braunova ´ A, Ulbrich K (2005) Poly(ethylene glycol)-based polymer carrier of
doxorubicin degradable by both enzymatic and chemical hydrolyses. Collect Czech Chem
Commun 70:327–338
120. Ramanathan S, Qiu B, Pooyan S, Zhang G, Stein S, Leibowitz MJ, Sinko PJ (2001) Targeted
PEG-based bioconjugates enhance the cellular uptake and transport of a HIV-1 TAT
nonapeptide. J Contr Release 77:199–212
121. d’Acunzo F, Kohn J (2002) Alternating multiblock amphiphilic copolymers of PEG
and tyrosine-derived diphenols. 1. Synthesis and characterization. Macromolecules
35:9360–9365
188
C. Dingels and H. Frey
sugar-PEG-based polymers for drug delivery applications. Biomacromolecules
12:3487–3498
102. Wang H-Y, Zhou Y-J, Wang Z, Wang N, Li K, Yu X-Q (2011) Enzyme-catalyzed synthesis
of a novel thermosensitive polyester with pendant ketoprofen. Macromol Biosci 11:595–599
103. Wang W, Tudryn GJ, Colby RH, Winey KI (2011) Thermally driven ionic aggregation in
poly(ethylene oxide)-based sulfonate ionomers. J Am Chem Soc 133:10826–10831
104. Braunova ´ A, Pechar M, Ulbrich K (2004) Degradation behavior of poly(ethylene glycol)
diblock and multiblock polymers with hydrolytically degradable ester linkages. Collect
Czech Chem Commun 69:1643–1656
105. Lee Y, Koo H, G-w J, Mo H, Cho MY, Park J-Y, Choi JS, Park JS (2005) Poly(ethylene oxide
sulfide): new poly(ethylene glycol) derivatives degradable in reductive conditions.
Biomacromolecules 6:24–26
106. Lee J, Joo MK, Kim J, Park JS, Yoon M-Y, Jeong B (2009) Temperature-sensitive biodegradable poly(ethylene glycol). J Biomater Sci Polym Ed 20:957–965
107. Etrych T, Kova ´r L, S ˇ ubr V, Braunova ´ A, Pechar M, Chytil P, R ˇ ı
´hova ´ B, Ulbrich K (2010)
High-molecular-weight polymers containing biodegradable disulfide bonds: synthesis and
in vitro verification of intracellular degradation. J Bioact Compat Polym 25:5–26
108. Hernandez-Mireles T, Rito-Palomares M (2006) New aqueous two-phase systems based on
poly(ethylene oxide sulfide) (PEOS) and potassium phosphate for the potential recovery of
proteins. J Chem Technol Biotechnol 81:997–1002
109. Reid B, Tzeng S, Warren A, Kozielski K, Elisseeff J (2010) Development of a PEG derivative
containing hydrolytically degradable hemiacetals. Macromolecules 43:9588–9590
110. Qi M, Li X, Yang Y, Zhou S (2008) Electrospun fibers of acid-labile biodegradable polymers
containing ortho ester groups for controlled release of paracetamol. Eur J Pharm Biopharm
70:445–452
111. Ulbrich K, Strohalm J, Kopec ˇek J (1986) Poly(ethylene glycol)s containing enzymatically
degradable bonds. Makromol Chem 187:1131–1144
112. Pechar M, Strohalm J, Ulbrich K (1995) Synthesis of poly(ethylene glycol) block copolymers
as potential water-soluble drug carriers. Collect Czech Chem Commun 60:1765–1780
113. Pechar M, Strohalm J, Ulbrich K, Schacht E (1997) Biodegradable drug carriers based on
poly(ethylene glycol) block copolymers. Macromol Chem Phys 198:1009–1020
114. Ulbrich K, Pechar M, Strohalm J, S ˇ ubr V, R ˇ ı
´hova ´ B (1997) Polymeric carriers of drugs for
site-specific therapy. Macromol Symp 118:577–585
115. Ulbrich K, S ˇ ubr V, Pechar M, Strohalm J, Jelı ´nkova ´ M, R ˇ ı
´hova ´ B (2000) Hydrophilic
polymers for drug delivery. Macromol Symp 152:151–162
116. Pechar M, Ulbrich K, S ˇ ubr V, Seymour LW, Schacht EH (2000) Poly(ethylene glycol)
multiblock copolymer as a carrier of anti-cancer drug doxorubicin. Bioconjugate Chem
11:131–139
117. Pechar M, Ulbrich K, Jelı ´nkova ´ M, R ˇ ı
´hova ´ B (2003) Conjugates of antibody-targeted PEG
multiblock polymers with doxorubicin in cancer therapy. Macromol Biosci 3:364–372
118. Pechar M, Braunova ´ A, Ulbrich K, Jelı ´nkova ´ M, R ˇ ı
´hova ´ B (2005) Poly(Ethylene Glycol)doxorubicin conjugates with pH-controlled activation. J Bioact Compat Polym 20:319–341
119. Pechar M, Braunova ´ A, Ulbrich K (2005) Poly(ethylene glycol)-based polymer carrier of
doxorubicin degradable by both enzymatic and chemical hydrolyses. Collect Czech Chem
Commun 70:327–338
120. Ramanathan S, Qiu B, Pooyan S, Zhang G, Stein S, Leibowitz MJ, Sinko PJ (2001) Targeted
PEG-based bioconjugates enhance the cellular uptake and transport of a HIV-1 TAT
nonapeptide. J Contr Release 77:199–212
121. d’Acunzo F, Kohn J (2002) Alternating multiblock amphiphilic copolymers of PEG
and tyrosine-derived diphenols. 1. Synthesis and characterization. Macromolecules
35:9360–9365
188
C. Dingels and H. Frey