Gao, T., Petrlova, J., He, W., Huser, T., Kudlick, W., Voss, J., Coleman, M.A. (2012) Characterization of de novo
synthesized GPCRs supported in nanolipoprotein discs. PLoS ONE 7:e44911.
Gao, Y., Cao, E., Julius, D., Cheng, Y. (2016) TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid
action. Nature 534:347–351.
Gatsogiannis, C., Merino, F., Prumbaum, D., Roderer, D., Leidreiter, F., Meusch, D., Raunser, S. (2016) Membrane
insertion of a Tc toxin in near-atomic detail. Nat. Struct. Mol. Biol. 23:884–890.
Gautier, A., Mott, H.R., Bostock, M.J., Kirkpatrick, J.P., Nietlispach, D. (2010) Structure determination of the sevenhelix transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy. Nat. Struct. Mol. Biol.
17:768–774.
Georgieva, E.R. (2017) Nanoscale lipid membrane mimetics in spin-labeling and electron paramagnetic resonance
spectroscopy studies of protein structure and function. Nanotech. Rev. 6:75–92.
Ghimire, H., Abu-Baker, S., Sahu, I.D., Zhou, A., Mayo, D.J., Lee, R.T., Lorigan, G.A. (2011) Probing the helical tilt
and dynamic properties of membrane-bound phospholamban in magnetically aligned bicelles using electron paramagnetic resonance spectroscopy. Biochim. Biophys. Acta 1818:645–650.
Gillette, W.K., Esposito, D., Abreu Blanco, M., Alexander, P., Bindu, L., Bittner, C., Chertov, O., Frank, P.H., Grose, C.,
Jones, J.E., Meng, Z., Perkins, S., Van, Q., Ghirlando, R., Fivash, M., Nissley, D.V., McCormick, F., Holderfield, M.,
Stephen, A.G. (2015) Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical
studies of prenylated protein-lipid interactions. Sci. Rep. 5:15916.
Goddard, A.D., Dijkman, P.M., Adamson, R.J., Inácio dos Reis, R., Watts, A. (2015) Reconstitution of membrane
proteins: A GPCR as an example. Meth. Enzymol. 556:405–424.
Gogol, E.P., Akkaladevi, N., Szerszen, L., Mukherjee, S., Chollet-Hinton, L., Katayama, H., Pentelute, B.L., Collier, R.
J., Fisher, M.T. (2013) Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryoelectron microscopy. Prot. Sci. 22:586–594.
Gogonea, V. (2016) Structural insights into high-density lipoprotein: Old models and new facts. Front. Pharmacol.
6:1–30.
Gogonea, V., Gerstenecker, G.S., Wu, Z., Lee, X., Topbas, C., Wagner, M.A., Tallant, T.C., Smith, J.D., Callow, P.,
Pipich, V., Malet, H., Schoehn, G., DiDonato, J.A., Hazen, S.L. (2013) The low-resolution structure of nHDL
reconstituted with DMPC with and without cholesterol reveals a mechanism for particle expansion. J. Lipid Res.
54:966–983.
Gregersen, J.L., Fedosova, N.U., Nissen, P., Boesen, T. (2016) Reconstitution of Na
+ ,K
+ -ATPase in nanodiscs. Methods
Mol. Biol. 1377:403–409.
Grigorieff, N., Ceska, T.A., Downing, K.H., Baldwin, J.M., Henderson, R. (1996) Electron-crystallographic refinement
of the structure of bacteriorhodopsin. J. Mol. Biol. 259:393–421.
Grinkova, Y.V., Denisov, I.G., Sligar, S.G. (2010) Engineering extended membrane scaffold proteins for self-assembly
of soluble nanoscale lipid bilayers. Protein Eng. Des. Sel. 23:843–848.
Gruene, T., Cho, M.-K., Karyagina, I., Kim, H.-Y., Grosse, C., Giller, K., Zweckstetter, M., Becker, S. (2011) Integrated
analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy.
J. Biomol. NMR 49:111–119.
Grushin, K., Miller, J., Dalm, D., Stoilova-McPhie, S. (2015) Factor VIII organisation on nanodiscs with different lipid
composition. Thromb. Haemost. 113:741–749.
Gustavsson, M., Traaseth, N.J., Veglia, G. (2012) Probing ground and excited states of phospholamban in model and
native lipid membranes by magic angle spinning NMR spectroscopy. Biochim. Biophys. Acta 1818:146–153.
Hagn, F., Etzkorn, M., Raschle, T., Wagner, G. (2013) Optimized phospholipid bilayer nanodiscs facilitate highresolution structure determination of membrane proteins. J. Am. Chem. Soc. 135:1919–1925.
Hagn, F., Wagner, G. (2015) Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscs. J. Biomol. NMR 61:249–260.
Han, S.G., Na, J.H., Lee, W.K., Park, D., Oh, J., Yoon, S.H., Lee, C.K., Sung, M.H., Shin, Y.K., Yu, Y.G. (2014) An
amphipathic polypeptide derived from poly-γ-glutamic acid for the stabilization of membrane proteins. Prot. Sci.
23:1800–1807.
Hansen, R.W., Wang, X., Golab, A., Bornert, O., Oswald, C., Wagner, R., Martinez, K.L. (2016) Functional stability of
the human κ-opioid receptor reconstituted in nanodiscs revealed by a time-resolved scintillation proximity assay.
PLoS ONE 11:e0150658.
Harroun, T.A., Koslowsky, M., Nieh, M.P., de Lannoy, C.F., Raghunathan, V.A., Katsaras, J. (2005) Comprehensive
examination of mesophases formed by DMPC and DHPC mixtures. Langmuir 21:5356–5361.
Held, P., Lach, F., Lebeau, L., Mioskowski, C. (1997) Synthesis and preliminary evaluation of a new class of
fluorinated amphiphiles designed for in-plane immobilisation of biological macromolecules. Tetrahedron Lett.
38:1937–1940.
Henrich, E., Dötsch, V., Bernhard, F. (2015) Screening for lipid requirements of membrane proteins by combining cellfree expression with nanodiscs. Meth. Enzymol. 556:351–369.
References
139
synthesized GPCRs supported in nanolipoprotein discs. PLoS ONE 7:e44911.
Gao, Y., Cao, E., Julius, D., Cheng, Y. (2016) TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid
action. Nature 534:347–351.
Gatsogiannis, C., Merino, F., Prumbaum, D., Roderer, D., Leidreiter, F., Meusch, D., Raunser, S. (2016) Membrane
insertion of a Tc toxin in near-atomic detail. Nat. Struct. Mol. Biol. 23:884–890.
Gautier, A., Mott, H.R., Bostock, M.J., Kirkpatrick, J.P., Nietlispach, D. (2010) Structure determination of the sevenhelix transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy. Nat. Struct. Mol. Biol.
17:768–774.
Georgieva, E.R. (2017) Nanoscale lipid membrane mimetics in spin-labeling and electron paramagnetic resonance
spectroscopy studies of protein structure and function. Nanotech. Rev. 6:75–92.
Ghimire, H., Abu-Baker, S., Sahu, I.D., Zhou, A., Mayo, D.J., Lee, R.T., Lorigan, G.A. (2011) Probing the helical tilt
and dynamic properties of membrane-bound phospholamban in magnetically aligned bicelles using electron paramagnetic resonance spectroscopy. Biochim. Biophys. Acta 1818:645–650.
Gillette, W.K., Esposito, D., Abreu Blanco, M., Alexander, P., Bindu, L., Bittner, C., Chertov, O., Frank, P.H., Grose, C.,
Jones, J.E., Meng, Z., Perkins, S., Van, Q., Ghirlando, R., Fivash, M., Nissley, D.V., McCormick, F., Holderfield, M.,
Stephen, A.G. (2015) Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical
studies of prenylated protein-lipid interactions. Sci. Rep. 5:15916.
Goddard, A.D., Dijkman, P.M., Adamson, R.J., Inácio dos Reis, R., Watts, A. (2015) Reconstitution of membrane
proteins: A GPCR as an example. Meth. Enzymol. 556:405–424.
Gogol, E.P., Akkaladevi, N., Szerszen, L., Mukherjee, S., Chollet-Hinton, L., Katayama, H., Pentelute, B.L., Collier, R.
J., Fisher, M.T. (2013) Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryoelectron microscopy. Prot. Sci. 22:586–594.
Gogonea, V. (2016) Structural insights into high-density lipoprotein: Old models and new facts. Front. Pharmacol.
6:1–30.
Gogonea, V., Gerstenecker, G.S., Wu, Z., Lee, X., Topbas, C., Wagner, M.A., Tallant, T.C., Smith, J.D., Callow, P.,
Pipich, V., Malet, H., Schoehn, G., DiDonato, J.A., Hazen, S.L. (2013) The low-resolution structure of nHDL
reconstituted with DMPC with and without cholesterol reveals a mechanism for particle expansion. J. Lipid Res.
54:966–983.
Gregersen, J.L., Fedosova, N.U., Nissen, P., Boesen, T. (2016) Reconstitution of Na
+ ,K
+ -ATPase in nanodiscs. Methods
Mol. Biol. 1377:403–409.
Grigorieff, N., Ceska, T.A., Downing, K.H., Baldwin, J.M., Henderson, R. (1996) Electron-crystallographic refinement
of the structure of bacteriorhodopsin. J. Mol. Biol. 259:393–421.
Grinkova, Y.V., Denisov, I.G., Sligar, S.G. (2010) Engineering extended membrane scaffold proteins for self-assembly
of soluble nanoscale lipid bilayers. Protein Eng. Des. Sel. 23:843–848.
Gruene, T., Cho, M.-K., Karyagina, I., Kim, H.-Y., Grosse, C., Giller, K., Zweckstetter, M., Becker, S. (2011) Integrated
analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy.
J. Biomol. NMR 49:111–119.
Grushin, K., Miller, J., Dalm, D., Stoilova-McPhie, S. (2015) Factor VIII organisation on nanodiscs with different lipid
composition. Thromb. Haemost. 113:741–749.
Gustavsson, M., Traaseth, N.J., Veglia, G. (2012) Probing ground and excited states of phospholamban in model and
native lipid membranes by magic angle spinning NMR spectroscopy. Biochim. Biophys. Acta 1818:146–153.
Hagn, F., Etzkorn, M., Raschle, T., Wagner, G. (2013) Optimized phospholipid bilayer nanodiscs facilitate highresolution structure determination of membrane proteins. J. Am. Chem. Soc. 135:1919–1925.
Hagn, F., Wagner, G. (2015) Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscs. J. Biomol. NMR 61:249–260.
Han, S.G., Na, J.H., Lee, W.K., Park, D., Oh, J., Yoon, S.H., Lee, C.K., Sung, M.H., Shin, Y.K., Yu, Y.G. (2014) An
amphipathic polypeptide derived from poly-γ-glutamic acid for the stabilization of membrane proteins. Prot. Sci.
23:1800–1807.
Hansen, R.W., Wang, X., Golab, A., Bornert, O., Oswald, C., Wagner, R., Martinez, K.L. (2016) Functional stability of
the human κ-opioid receptor reconstituted in nanodiscs revealed by a time-resolved scintillation proximity assay.
PLoS ONE 11:e0150658.
Harroun, T.A., Koslowsky, M., Nieh, M.P., de Lannoy, C.F., Raghunathan, V.A., Katsaras, J. (2005) Comprehensive
examination of mesophases formed by DMPC and DHPC mixtures. Langmuir 21:5356–5361.
Held, P., Lach, F., Lebeau, L., Mioskowski, C. (1997) Synthesis and preliminary evaluation of a new class of
fluorinated amphiphiles designed for in-plane immobilisation of biological macromolecules. Tetrahedron Lett.
38:1937–1940.
Henrich, E., Dötsch, V., Bernhard, F. (2015) Screening for lipid requirements of membrane proteins by combining cellfree expression with nanodiscs. Meth. Enzymol. 556:351–369.
References
139