47. Tadic D, Epple M (2004) A thorough physicochemical characterisation of 14 calcium
phosphate-based bone substitution materials in comparison to natural bone. Biomaterials
25(6):987–994
48. Ramay HRR, Zhang M (2004) Biphasic calcium phosphate nanocomposite porous scaffolds
for load-bearing bone tissue engineering. Biomaterials 25(21):5171–5180
49. Pielichowska K, Blazewicz S (2010) Bioactive Polymer/Hydroxyapatite (Nano)composites
for Bone Tissue Regeneration. Adv Polym Sci 232: 97–207
50. Murugan R, Ramakrishna S (2005) Aqueous mediated synthesis of bioresorbable
nanocrystalline hydroxyapatite. J Cryst Growth 274:209–213
51. Murugan R, Ramakrishna S (2006) Production of ultra-fine bioresorbable carbonated
hydroxyapatite. Acta Biomater 2:201–206
52. Nihouannen DL, Saffarzadeh A, Gauthier O (2008) Bone tissue formation in sheep muscles
induced by a biphasic calcium phosphate ceramic and fibrin glue composite. J Mater Sci
Mater Med 19:667–675
53. Siddharthan A, Seshadri SK, Sampath Kumar TS (2004) Microwave accelerated synthesis of
nanosized calcium deficient hydroxyapatite. J Mater Sci Mater Med 15:1279–1284
54. Hao J, Liu Y, Zhou S (2003) Investigation of nanocomposites based on semiinterpenetrating
network of [L-poly(E-caprolactone)]/[net-poly(E-caprolactone)] and hydroxyapatite
nanocrystals. Biomaterials 24:1531–1539
55. Deng X, Hao JY, Wang C (2001) Preparation and mechanical properties of nanocomposites
of poly(D, L-lactide) with Ca-deffcient hydroxyapatite nanocrystals. Biomaterials
22:2867–2873
56. Slosarczyk A, Paszkiewicz Z, Paluszkiewicz C (2005) FTIR and XRD evaluation of
carbonated hydroxyapatite powders synthesized by wetmethods. J Mol Struct
744–747:657–661
57. Rapacz-Kmita A, Cz P, Slosarczyk A (2005) FTIR and XRD investigations on the thermal
stability of hydroxyapatite during hot pressing and pressureless sintering processes. J Mol
Struct 744–747:653–656
58. Zhang Y, Zhou L, Xue N (2003) Oriented nano-structured hydroxyapatite from the template.
Chem Phys Lett 376:493–497
59. Zhou WY, Wang M, Cheung WL (2008) Synthesis of carbonated hydroxyapatite
nanospheres through nanoemulsion. J Mater Sci Mater Med 19:103–110
60. Solans C, Izquierdo P, Nolla J (2005) Nano-emulsions. Curr Opin Coll Interface Sci
10:102–110
61. Landi E, Logroscino G, Proietti L (2008) Biomimetic Mg-substituted hydroxyapatite: from
synthesis to in vivo behaviour. J Mater Sci Mater Med 19:239–247
62. Ogiso M (1998) Reassessment of long-term use of dense HA as dental implant: case report.
J Biomed Mater Res 43(3):318–320
63. Chu TMG, Orton DG, Hollister SJ, Feinberg SE, Halloran JW (2002) Mechanical and in vivo
performance of hydroxyapatite implants with controlled architectures. Biomaterials 23
(5):1283–1293
64. Ayers RA, Simske SJ, Nunes CR, Wolford LM (1998) Long-term bone ingrowth and residual
microhardness of porous block hydroxyapatite implants in humans. J Oral Maxillofac Surg 56
(11):1297–1301
65. Le Guθhennec L, Soueidan A, Layrolle P, Amouriq Y (2007) Surface treatments of titanium
dental implants for rapid osseointegration. Dent Mater 23(7):844–854
66. Fathi MH, Salehi M, Saatchi A, Mortazavi V, Moosavi SB (2003) In vitro corrosion behavior
of bioceramic, metallic, and bioceramic-metallic coated stainless steel dental implants. Dent
Mater 19(3):188–198
67. Schmitz JP, Hollinger JO, Milam SB (1999) Reconstruction of bone using calcium phosphate
bone cements: a critical review. J Oral Maxillofac Surg 57(9):1122–1126
Hydroxyapatite-Packed Chitosan-PMMA Nanocomposite: A Promising Material for. . .
163
phosphate-based bone substitution materials in comparison to natural bone. Biomaterials
25(6):987–994
48. Ramay HRR, Zhang M (2004) Biphasic calcium phosphate nanocomposite porous scaffolds
for load-bearing bone tissue engineering. Biomaterials 25(21):5171–5180
49. Pielichowska K, Blazewicz S (2010) Bioactive Polymer/Hydroxyapatite (Nano)composites
for Bone Tissue Regeneration. Adv Polym Sci 232: 97–207
50. Murugan R, Ramakrishna S (2005) Aqueous mediated synthesis of bioresorbable
nanocrystalline hydroxyapatite. J Cryst Growth 274:209–213
51. Murugan R, Ramakrishna S (2006) Production of ultra-fine bioresorbable carbonated
hydroxyapatite. Acta Biomater 2:201–206
52. Nihouannen DL, Saffarzadeh A, Gauthier O (2008) Bone tissue formation in sheep muscles
induced by a biphasic calcium phosphate ceramic and fibrin glue composite. J Mater Sci
Mater Med 19:667–675
53. Siddharthan A, Seshadri SK, Sampath Kumar TS (2004) Microwave accelerated synthesis of
nanosized calcium deficient hydroxyapatite. J Mater Sci Mater Med 15:1279–1284
54. Hao J, Liu Y, Zhou S (2003) Investigation of nanocomposites based on semiinterpenetrating
network of [L-poly(E-caprolactone)]/[net-poly(E-caprolactone)] and hydroxyapatite
nanocrystals. Biomaterials 24:1531–1539
55. Deng X, Hao JY, Wang C (2001) Preparation and mechanical properties of nanocomposites
of poly(D, L-lactide) with Ca-deffcient hydroxyapatite nanocrystals. Biomaterials
22:2867–2873
56. Slosarczyk A, Paszkiewicz Z, Paluszkiewicz C (2005) FTIR and XRD evaluation of
carbonated hydroxyapatite powders synthesized by wetmethods. J Mol Struct
744–747:657–661
57. Rapacz-Kmita A, Cz P, Slosarczyk A (2005) FTIR and XRD investigations on the thermal
stability of hydroxyapatite during hot pressing and pressureless sintering processes. J Mol
Struct 744–747:653–656
58. Zhang Y, Zhou L, Xue N (2003) Oriented nano-structured hydroxyapatite from the template.
Chem Phys Lett 376:493–497
59. Zhou WY, Wang M, Cheung WL (2008) Synthesis of carbonated hydroxyapatite
nanospheres through nanoemulsion. J Mater Sci Mater Med 19:103–110
60. Solans C, Izquierdo P, Nolla J (2005) Nano-emulsions. Curr Opin Coll Interface Sci
10:102–110
61. Landi E, Logroscino G, Proietti L (2008) Biomimetic Mg-substituted hydroxyapatite: from
synthesis to in vivo behaviour. J Mater Sci Mater Med 19:239–247
62. Ogiso M (1998) Reassessment of long-term use of dense HA as dental implant: case report.
J Biomed Mater Res 43(3):318–320
63. Chu TMG, Orton DG, Hollister SJ, Feinberg SE, Halloran JW (2002) Mechanical and in vivo
performance of hydroxyapatite implants with controlled architectures. Biomaterials 23
(5):1283–1293
64. Ayers RA, Simske SJ, Nunes CR, Wolford LM (1998) Long-term bone ingrowth and residual
microhardness of porous block hydroxyapatite implants in humans. J Oral Maxillofac Surg 56
(11):1297–1301
65. Le Guθhennec L, Soueidan A, Layrolle P, Amouriq Y (2007) Surface treatments of titanium
dental implants for rapid osseointegration. Dent Mater 23(7):844–854
66. Fathi MH, Salehi M, Saatchi A, Mortazavi V, Moosavi SB (2003) In vitro corrosion behavior
of bioceramic, metallic, and bioceramic-metallic coated stainless steel dental implants. Dent
Mater 19(3):188–198
67. Schmitz JP, Hollinger JO, Milam SB (1999) Reconstruction of bone using calcium phosphate
bone cements: a critical review. J Oral Maxillofac Surg 57(9):1122–1126
Hydroxyapatite-Packed Chitosan-PMMA Nanocomposite: A Promising Material for. . .
163