4 Polymer-Type CSPs
Figure 3 shows examples of the polymer-type CSPs [4, 5, 8]. Various chiral
polymers including polymethacrylates (3,4), poly[(meth)acrylamides] (5,6),
polymaleimide (7), polyacetylenes (8,9), poly(α-amino acid) (10,11), polyamides
(12–14), polyurethane (15), proteins (16), and polysaccharide derivatives (17,18)
have been evaluated as CSPs.
C
C O
O
C
CH 2
CH 3
NHCOH
NH
CO
n
Protein
n
m
CO 2 R'
CH
CH 2
C
C
CH 3 (H)
O
NH
CH 2
NH
NHCO R CO
CONH(CH 2 ) 6 NH
C
O
CH
R
H
N H
O C
O
NH R' NH C
O
O
R
R
CH 2 CH
CH 2 NH(COCHNH)
CH 2
CH 2 CONHCH 2
COCH 3
OR
O
RO
OR
O
OR
O
RO
OR
O
C
C
O
N R N
O
OR'
H
H
OR'
n
n
n
n
R=CH 3 , Ph
R'=
2 ) n
n
3
5
7
11
8
10
15
16
12
9
R=
2 ) n n=6,8,10 ,
n
R'=H, CONHPr, CONHPh
18
C
C O
O
C
CH 2
CH 3
N
n
4
R'=
3 ,
2 CH 3
OCONH
H
R
CH 3
n
R=
,
13
C
C
CH 3
O
NH
CH 2
CH-CO 2 CH 3
n
6
CONH
n
14
N
O
O
n
17
CO 2 Et
Fig. 3 Structures of polymer-type CSPs
Helical Polymers for Efficient Enantiomer Separation
395