202. Matyjaszewski K (1997) Controlled radical polymerization, ACS Symposium Series,
vol 685. American Chemical Society, Washington
203. Shen Y, Zhu S, Pelton R (2000) Packed column reactor for continuous atom transfer radical
polymerization: methyl methacrylate polymerization using silica gel supported catalyst.
Macromol Rapid Commun 21:956–959
204. Shen Y, Zhu S (2002) Continuous atom transfer radical block copolymerization of
methacrylates. AIChE J 48:2609–2619
205. Wu T, Mei Y, Cabral JT et al (2004) A new synthetic method for controlled polymerization
using a microfluidic system. J Am Chem Soc 126:9880–9881
206. Save M, Weaver JVM, Armes SP et al (2002) Atom transfer radical polymerization of
hydroxy-functional methacrylates at ambient temperature: comparison of glycerol
monomethacrylate with 2-hydroxypropyl methacrylate. Macromolecules 35:1152–1159
207. Wu T, Mei Y, Xu C et al (2005) Block copolymer PEO-b-PHPMA synthesis using controlled
radical polymerization on a chip. Macromol Rapid Commun 26:1037–1042
208. Russum JP, Jones CW, Schork FJ (2004) Continuous reversible addition-fragmentation chain
transfer polymerization in miniemulsion utilizing a multi-tube reaction system. Macromol
Rapid Commun 25:1064–1068
209. Russum JP, Jones CW, Schork FJ (2005) Continuous living polymerization in miniemulsion
using reversible addition fragmentation chain transfer (RAFT) in a tubular reactor. Ind Eng
Chem Res 44:2484–2493
210. Diehl C, Laurino P, Azzouz N et al (2010) Accelerated continuous flow RAFT polymerization. Macromolecules 43:10311–10314
211. Hornung CH, Guerrero-Sanchez C, Brasholz M et al (2011) Controlled RAFT polymerization
in a continuous flow microreactor. Org Process Res Dev 15:593–601
212. Rosenfeld C, Serra C, Brochon C et al (2007) High-temperature nitroxide-mediated radical
polymerization in a continuous microtube reactor: towards a better control of the polymerization reaction. Chem Eng Sci 62:5245–5250
213. Enright TE, Cunningham MF, Keoshkerian B (2005) Nitroxide-mediated polymerization of
styrene in a continuous tubular reactor. Macromol Rapid Commun 26:221–225
214. Enright TE, Cunningham MF, Keoshkerian B (2010) Nitroxide-mediated bulk and
miniemulsion polymerization in a continuous tubular reactor: synthesis of homo-, di- and
triblock copolymers. Macromol React Eng 4:186–196
215. Rosenfeld C, Serra C, Brochon C et al (2008) Use of micromixers to control the molecular
weight distribution in continuous two-stage nitroxide-mediated copolymerizations. Chem
Eng J 135S:S242–S246
216. Rosenfeld C, Serra C, Brochon C et al (2008) Influence of micromixer characteristics on
polydispersity index of block copolymers synthesized in continuous flow microreactors. Lab
Chip 8:1682–1687
217. Miele S, Nesvadba P, Studer A (2009) 1-tert-Butyl-3,3,5,5-tetraalkyl-2-piperazinon-4-oxyls:
highly efficient nitroxides for controlled radical polymerization. Macromolecules
42:2419–2427
218. Knoop CA, Studer A (2003) Hydroxy- and silyloxy-substituted TEMPO derivatives for the
living free-radical polymerization of styrene and n-butyl acrylate: synthesis, kinetics, and
mechanistic studies. J Am Chem Soc 125:16327–16333
219. Fukuyama T, Kajihara Y, Ryu I et al (2012) Nitroxide-mediated polymerization of styrene,
butyl acrylate, or methyl methacrylate by microflow reactor technology. Synthesis
44:2555–2559
220. Rosenfeld C, Serra C, O’Donohue S et al (2007) Continuous online rapid size exclusion
chromatography monitoring of polymerizations – CORSEMP. Macromol React Eng
1:547–552
221. Zitlalpopoca-Soriano AG, Vivaldo-Lima E, Flores-Tlacuahuac A (2010) Bifurcation analysis
of a tubular reactor for nitroxide-mediated radical polymerization of styrene. Macromol
React Eng 4:599–612
48
A. Nagaki and J.-i. Yoshida
vol 685. American Chemical Society, Washington
203. Shen Y, Zhu S, Pelton R (2000) Packed column reactor for continuous atom transfer radical
polymerization: methyl methacrylate polymerization using silica gel supported catalyst.
Macromol Rapid Commun 21:956–959
204. Shen Y, Zhu S (2002) Continuous atom transfer radical block copolymerization of
methacrylates. AIChE J 48:2609–2619
205. Wu T, Mei Y, Cabral JT et al (2004) A new synthetic method for controlled polymerization
using a microfluidic system. J Am Chem Soc 126:9880–9881
206. Save M, Weaver JVM, Armes SP et al (2002) Atom transfer radical polymerization of
hydroxy-functional methacrylates at ambient temperature: comparison of glycerol
monomethacrylate with 2-hydroxypropyl methacrylate. Macromolecules 35:1152–1159
207. Wu T, Mei Y, Xu C et al (2005) Block copolymer PEO-b-PHPMA synthesis using controlled
radical polymerization on a chip. Macromol Rapid Commun 26:1037–1042
208. Russum JP, Jones CW, Schork FJ (2004) Continuous reversible addition-fragmentation chain
transfer polymerization in miniemulsion utilizing a multi-tube reaction system. Macromol
Rapid Commun 25:1064–1068
209. Russum JP, Jones CW, Schork FJ (2005) Continuous living polymerization in miniemulsion
using reversible addition fragmentation chain transfer (RAFT) in a tubular reactor. Ind Eng
Chem Res 44:2484–2493
210. Diehl C, Laurino P, Azzouz N et al (2010) Accelerated continuous flow RAFT polymerization. Macromolecules 43:10311–10314
211. Hornung CH, Guerrero-Sanchez C, Brasholz M et al (2011) Controlled RAFT polymerization
in a continuous flow microreactor. Org Process Res Dev 15:593–601
212. Rosenfeld C, Serra C, Brochon C et al (2007) High-temperature nitroxide-mediated radical
polymerization in a continuous microtube reactor: towards a better control of the polymerization reaction. Chem Eng Sci 62:5245–5250
213. Enright TE, Cunningham MF, Keoshkerian B (2005) Nitroxide-mediated polymerization of
styrene in a continuous tubular reactor. Macromol Rapid Commun 26:221–225
214. Enright TE, Cunningham MF, Keoshkerian B (2010) Nitroxide-mediated bulk and
miniemulsion polymerization in a continuous tubular reactor: synthesis of homo-, di- and
triblock copolymers. Macromol React Eng 4:186–196
215. Rosenfeld C, Serra C, Brochon C et al (2008) Use of micromixers to control the molecular
weight distribution in continuous two-stage nitroxide-mediated copolymerizations. Chem
Eng J 135S:S242–S246
216. Rosenfeld C, Serra C, Brochon C et al (2008) Influence of micromixer characteristics on
polydispersity index of block copolymers synthesized in continuous flow microreactors. Lab
Chip 8:1682–1687
217. Miele S, Nesvadba P, Studer A (2009) 1-tert-Butyl-3,3,5,5-tetraalkyl-2-piperazinon-4-oxyls:
highly efficient nitroxides for controlled radical polymerization. Macromolecules
42:2419–2427
218. Knoop CA, Studer A (2003) Hydroxy- and silyloxy-substituted TEMPO derivatives for the
living free-radical polymerization of styrene and n-butyl acrylate: synthesis, kinetics, and
mechanistic studies. J Am Chem Soc 125:16327–16333
219. Fukuyama T, Kajihara Y, Ryu I et al (2012) Nitroxide-mediated polymerization of styrene,
butyl acrylate, or methyl methacrylate by microflow reactor technology. Synthesis
44:2555–2559
220. Rosenfeld C, Serra C, O’Donohue S et al (2007) Continuous online rapid size exclusion
chromatography monitoring of polymerizations – CORSEMP. Macromol React Eng
1:547–552
221. Zitlalpopoca-Soriano AG, Vivaldo-Lima E, Flores-Tlacuahuac A (2010) Bifurcation analysis
of a tubular reactor for nitroxide-mediated radical polymerization of styrene. Macromol
React Eng 4:599–612
48
A. Nagaki and J.-i. Yoshida