Table 4
(continued)
MSC source Bioreactor system
WV
Microcarrier/coating
Culture medium
Agitation
Cell density
Ref.
hASC
125 mL Corning
spinner
100 mL ProNectin-F
Lonza medium+5%
FBS
49 rpm
0.58–1.25
 10
6
cells/mL
[11, 62]
100 mL BellCo
spinner
80 mL
Synthemax II
StemPro MSC
40 rpm
0.19
 10
6
cells/mL
[68]
BioBLU
®
5c
3.75 L
Polystyrene-based
MC
MSC medium ATCC
25-35 rpm
0.04
 10
6
cells/mL
[76]
BioBLU
®
5c
3.75 L
Collagen-coated MC
25-35 rpm
0.24
 10
6
cells/mL
[76]
UniVessel
®
SU 2L
2 L
ProNectin-F
Lonza medium+5%
FBS
100-140
rpm
0.27
 10
6
cells/mL
[62]
BIOSTAT
®
STR 50L
35 L
ProNectin-F
50-66 rpm
0.31
 10
6
cells/mL
[62]
hTERTASC
125 mL Corning
spinner
100 mL ProNectin-F
49 rpm
0.63
 10
6
cells/mL
[12]
500 mL Corning
spinner
300 mL ProNectin-F
52 rpm
0.88
 10
6
cells/mL
[12]
198
V. Jossen et al.