168
N. N. Win and H. Morita
Fig. 35 Structures of
165–167 isolated from
ethanolic extract of V. repens
rhizomes
O
O
HO
O
OH
OH
OAc
OH
O
166 (11-O-acetyl-bergenin)
167 (stigmast-4-en-3-one)
O
HO
OH
OH
165 ((E)-resveratrol)
assay testing procedure used revealed for the first time that resveratrol, 11-O-acetylbergenin, and stigmast-4-en-3-one possess antitrypanosomal activities, with IC 50
values of 0.13, 0.17, and 0.15 μM, respectively [187].
2.10 Boesenbergia pandurata (Roxb.) Schltr. (Boesenbergia
rotunda (L.) Mansf.)
Boesenbergia pandurata (Roxb.) Schltr., a perennial herb of the Zingiberaceae family, is cultivated in some tropical countries, including Myanmar,
Indonesia, Malaysia, and Thailand [160]. This plant has eight different botanical
synonyms, namely, Boesenbergia cochinchinensis (Gagnep.) Loes., Boesenbergia
pandurata (Roxb.) Schltr., Curcuma rotunda L., Gastrochilus panduratus (Roxb.)
Ridl., Gastrochilus rotundus (L.) Alston, Kaempferia cochinchinensis Gagnep.,
Kaempferia ovata Roscoe, and Kaempferia pandurata Roxb. Currently, it is known
as Boesenbergia rotunda (L.) Mansf. [197]. In Myanmar, this plant is referred colloquially as Seik-phoo (Fig. 36), and its rhizomes have been included in the TMF-47
(Khu-na-pah-hsay-wa-ga-lay), used for the treatment of asthma, diarrhea, indigestion, itching, and fever [198]. The rhizomes are also a popular folk medicine for
diseases such as ulcers, dry mouth, stomach discomfort, leucorrhea, and dysentery in Indonesia, Malaysia, and Thailand [199]. The fresh rhizomes have a characteristic aroma and are used as flavoring agent in Thai cuisine [200]. They have
also been employed as a self-medication by HIV/AIDS patients in Thailand [201].
Previous investigations on B. pandurata have reported anti-HIV [202], antibacterial [203], anti-inflammatory, analgesic, antipyretic [199, 204, 205], cytotoxic [206],
antioxidant [207], and insecticidal activities [208].
N. N. Win and H. Morita
Fig. 35 Structures of
165–167 isolated from
ethanolic extract of V. repens
rhizomes
O
O
HO
O
OH
OH
OAc
OH
O
166 (11-O-acetyl-bergenin)
167 (stigmast-4-en-3-one)
O
HO
OH
OH
165 ((E)-resveratrol)
assay testing procedure used revealed for the first time that resveratrol, 11-O-acetylbergenin, and stigmast-4-en-3-one possess antitrypanosomal activities, with IC 50
values of 0.13, 0.17, and 0.15 μM, respectively [187].
2.10 Boesenbergia pandurata (Roxb.) Schltr. (Boesenbergia
rotunda (L.) Mansf.)
Boesenbergia pandurata (Roxb.) Schltr., a perennial herb of the Zingiberaceae family, is cultivated in some tropical countries, including Myanmar,
Indonesia, Malaysia, and Thailand [160]. This plant has eight different botanical
synonyms, namely, Boesenbergia cochinchinensis (Gagnep.) Loes., Boesenbergia
pandurata (Roxb.) Schltr., Curcuma rotunda L., Gastrochilus panduratus (Roxb.)
Ridl., Gastrochilus rotundus (L.) Alston, Kaempferia cochinchinensis Gagnep.,
Kaempferia ovata Roscoe, and Kaempferia pandurata Roxb. Currently, it is known
as Boesenbergia rotunda (L.) Mansf. [197]. In Myanmar, this plant is referred colloquially as Seik-phoo (Fig. 36), and its rhizomes have been included in the TMF-47
(Khu-na-pah-hsay-wa-ga-lay), used for the treatment of asthma, diarrhea, indigestion, itching, and fever [198]. The rhizomes are also a popular folk medicine for
diseases such as ulcers, dry mouth, stomach discomfort, leucorrhea, and dysentery in Indonesia, Malaysia, and Thailand [199]. The fresh rhizomes have a characteristic aroma and are used as flavoring agent in Thai cuisine [200]. They have
also been employed as a self-medication by HIV/AIDS patients in Thailand [201].
Previous investigations on B. pandurata have reported anti-HIV [202], antibacterial [203], anti-inflammatory, analgesic, antipyretic [199, 204, 205], cytotoxic [206],
antioxidant [207], and insecticidal activities [208].